相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer's disease pathologies
Yiyuan Xia et al.
MOLECULAR PSYCHIATRY (2021)
Control of cell death/survival balance by the MET dependence receptor
Leslie Duplaquet et al.
ELIFE (2020)
Gamma-secretase-dependent signaling of receptor tyrosine kinases
Johannes A. M. Merilahti et al.
ONCOGENE (2019)
EPHA2 Is a Predictive Biomarker of Resistance and a Potential Therapeutic Target for Improving Antiepidermal Growth Factor Receptor Therapy in Colorectal Cancer
Giulia Martini et al.
MOLECULAR CANCER THERAPEUTICS (2019)
EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions
Jean Defourny et al.
ISCIENCE (2019)
MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells
Kyu-Yeon Han et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2019)
Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons
Christopher R. Donnelly et al.
JOURNAL OF CELL BIOLOGY (2018)
Mechanisms of receptor tyrosine kinase activation in cancer
Zhenfang Du et al.
MOLECULAR CANCER (2018)
The beta secretase BACE1 regulates the expression of insulin receptor in the liver
Paul J. Meakin et al.
NATURE COMMUNICATIONS (2018)
Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells
Yinzhong Lu et al.
FASEB JOURNAL (2017)
Genome-wide screen of gamma-secretase-mediated intramembrane cleavage of receptor tyrosine kinases
Johannes A. M. Merilahti et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis
Wen-Hsuan Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases
Li-Mei Chen et al.
ONCOTARGET (2017)
MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering
Remi Montagne et al.
ONCOTARGET (2017)
Collagen induces activation of DDR1 through lateral dimer association and phosphorylation between dimers
Victoria Juskaite et al.
ELIFE (2017)
Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer
Oskar Eriksson et al.
BMC CANCER (2016)
Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE
Jacob J. Orme et al.
CLINICAL IMMUNOLOGY (2016)
Sequential cleavage of insulin receptor by calpain 2 and γ-secretase impairs insulin signalling
Tomoyuki Yuasa et al.
DIABETOLOGIA (2016)
Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling
Sarah B. Mueller et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Brain ischaemia induces shedding of a BDNF-scavenger ectodomain from TrkB receptors by excitotoxicity activation of metalloproteinases and γ-secretases
Gonzalo S. Tejeda et al.
JOURNAL OF PATHOLOGY (2016)
Calpain-dependent truncated form of TrkB-FL increases in neurodegenerative processes
Victor Danelon et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2016)
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance
Miles A. Miller et al.
CANCER DISCOVERY (2016)
Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis
Kyu-Yeon Han et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2016)
ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1)
Yasuyuki Shitomi et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
Necrosis- and apoptosis-related Met cleavages have divergent functional consequences
R. Montagne et al.
CELL DEATH & DISEASE (2015)
Potential Role of Soluble c-Met as a New Candidate Biomarker of Metastatic Uveal Melanoma
Gaia Barisione et al.
JAMA OPHTHALMOLOGY (2015)
Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain
Andre Jeronimo-Santos et al.
CEREBRAL CORTEX (2015)
MMP14 Cleavage of VEGFR1 in the Cornea Leads to a VEGF-Trap Antiangiogenic Effect
Kyu-Yeon Han et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
Identification and mutagenesis of the TACE and γ-secretase cleavage sites in the colony-stimulating factor 1 receptor
Arrash Vahidi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
EphA4 Receptor Shedding Regulates Spinal Motor Axon Guidance
Graziana Gatto et al.
CURRENT BIOLOGY (2014)
Protein-tyrosine Pseudokinase 7 (PTK7) Directs Cancer Cell Motility and Metastasis
Vladislav S. Golubkov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Eph Tyrosine Kinase Receptors EphB2 and EphA2 Are Novel Proteolytic Substrates of Tissue Factor/Coagulation Factor VIIa
Oskar Eriksson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Serine Protease Granzyme B as an Inflammatory Marker, in Relation to the Insulin Receptor Cleavage in Human Obesity and Type 2 Diabetes Mellitus
Hala O. El Mesallamy et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2014)
Crosstalk Between Nuclear MET and SOX9/β-Catenin Correlates with Castration-Resistant Prostate Cancer
Yingqiu Xie et al.
MOLECULAR ENDOCRINOLOGY (2014)
ADAM12-cleaved ephrin-A1 contributes to lung metastasis
K. Ieguchi et al.
ONCOGENE (2014)
N-Terminal Cleavage and Release of the Ectodomain of Flt1 Is Mediated via ADAM10 and ADAM 17 and Regulated by VEGFR2 and the Flt1 Intracellular Domain
Nandita S. Raikwar et al.
PLOS ONE (2014)
The ErbB/HER family of protein-tyrosine kinases and cancer
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2014)
Insulin Receptor Signaling in Normal and Insulin-Resistant States
Jeremie Boucher et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer
Katharina Feldinger et al.
ONCOTARGET (2014)
The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity
Cendrine Tourette et al.
PLOS BIOLOGY (2014)
Bringing cancer serological diagnosis to a new level: focusing on HER2, protein ectodomain shedding and neoepitope technology
Jianxia Wang et al.
FUTURE ONCOLOGY (2013)
Shedding of Discoidin Domain Receptor 1 by Membrane-type Matrix Metalloproteinases
Hsueh-Liang Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment
Gabriel Ichim et al.
MOLECULAR CELL (2013)
A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYK
Michael M. Halford et al.
PLOS ONE (2013)
ADAM-10 and-17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling
Miles A. Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity
J. Lefebvre et al.
CELL DEATH & DISEASE (2013)
HER2 shedding and serum HER2 extracellular domain: Biology and clinical utility in breast cancer
Chantal Tse et al.
CANCER TREATMENT REVIEWS (2012)
Eph-dependent cell-cell adhesion and segregation in development and cancer
Eva Nievergall et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
ß-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment
Jun Cai et al.
EMBO MOLECULAR MEDICINE (2012)
The Cytosolic Domain of Protein-tyrosine Kinase 7 (PTK7), Generated from Sequential Cleavage by a Disintegrin and Metalloprotease 17 (ADAM17) and γ-Secretase, Enhances Cell Proliferation and Migration in Colon Cancer Cells
Hye-Won Na et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Interaction with ErbB4 Promotes Hypoxia-inducible Factor-1α Signaling
Ilkka Paatero et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Insights into Ectodomain Shedding and Processing of Protein-tyrosine Pseudokinase 7 (PTK7)
Vladislav S. Golubkov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior
Athina-Myrto Chioni et al.
JOURNAL OF CELL BIOLOGY (2012)
Proteolytic Processing of ErbB4 in Breast Cancer
Maija Hollmen et al.
PLOS ONE (2012)
Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity
O. G. Vidaurre et al.
CELL DEATH & DISEASE (2012)
Spatial regulation of receptor tyrosine kinases in development and cancer
Jessica B. Casaletto et al.
NATURE REVIEWS CANCER (2012)
Neuregulin Receptor ErbB4 Functions as a Transcriptional Cofactor for the Expression of Surfactant Protein B in the Fetal Lung
Katja Zscheppang et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
Molecular control of angiopoietin signalling
Harprit Singh et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2011)
Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation
Kristina Hoeing et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Estrogen-induced upregulation of Sftpb requires transcriptional control of neuregulin receptor ErbB4 in mouse lung type II epithelial cells
Katja Zscheppang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Emerging strategies for EphA2 receptor targeting for cancer therapeutics
Manish Tandon et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2011)
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis
Wendy van Veelen et al.
GUT (2011)
RET Modulates Cell Adhesion via Its Cleavage by Caspase in Sympathetic Neurons
Jorge R. Cabrera et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Potential Relation of Aberrant Proteolysis of Human Protein Tyrosine Kinase 7 (PTK7) chuzhoi by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) to Congenital Defects
Vladislav S. Golubkov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
γ-Secretase and Presenilin Mediate Cleavage and Phosphorylation of Vascular Endothelial Growth Factor Receptor-1
Jun Cai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)
Edward Thorp et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Ligand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3
Catherine R. Degnin et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Cell Signaling by Receptor Tyrosine Kinases
Mark A. Lemmon et al.
CELL (2010)
Stimulation of Platelet-derived Growth Factor Receptor β (PDGFRβ) Activates ADAM17 and Promotes Metalloproteinase-dependent Cross-talk between the PDGFRβ and Epidermal Growth Factor Receptor (EGFR) Signaling Pathways
Karen Mendelson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Disintegrin and Metalloproteinase-10 (ADAM-10) Mediates DN30 Antibody-induced Shedding of the Met Surface Receptor
Florian Schelter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Up-Regulation of Soluble Axl and Mer Receptor Tyrosine Kinases Negatively Correlates with Gas6 in Established Multiple Sclerosis Lesions
Jason G. Weinger et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
EphrinB3 is an anti-apoptotic ligand that inhibits the dependence receptor functions of EphA4 receptors during adult neurogenesis
Celine Furne et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
ALK (Anaplastic Lymphoma Kinase) expression in DRG neurons and its involvement in neuron-Schwann cells interaction
Joffrey Degoutin et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Cdc37 Regulates Ryk Signaling by Stabilizing the Cleaved Ryk Intracellular Domain
Jungmook Lyu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Peptide EphB2/CTF2 Generated by the γ-Secretase Processing of EphB2 Receptor Promotes Tyrosine Phosphorylation and Cell Surface Localization of N-Methyl-D-aspartate Receptors
Jindong Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Synaptic activity prompts γ-secretase-mediated cleavage of EphA4 and dendritic spine formation
Eiji Inoue et al.
JOURNAL OF CELL BIOLOGY (2009)
Down-Regulation of the Met Receptor Tyrosine Kinase by Presenilin-dependent Regulated Intramembrane Proteolysis
Benedicte Foveau et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
VEGF-A Stimulates ADAM17-Dependent Shedding of VEGFR2 and Crosstalk Between VEGFR2 and ERK Signaling
Steven Swendeman et al.
CIRCULATION RESEARCH (2008)
Cleavage of the Wnt Receptor Ryk Regulates Neuronal Differentiation during Cortical Neurogenesis
Jungmook Lyu et al.
DEVELOPMENTAL CELL (2008)
Caspase cleavage of HER-2 releases a bad-like cell death effector
Anne M. Strohecker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The ADAM metalloproteinases
Dylan R. Edwards et al.
MOLECULAR ASPECTS OF MEDICINE (2008)
Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2
Marie B. Marron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Generation of intracellular domain of insulin receptor tyrosine kinase by γ-secretase
K. Kasuga et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm
Servane Tauszig-Delamasure et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Soluble insulin receptor ectodomain is elevated in the plasma of patients with diabetes
Toshiyuki Obata et al.
DIABETES (2007)
Receptor tyrosine kinases: mechanisms of activation and signaling
Stevan R. Hubbard et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis
Carly R. K. Loeb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells
Rebecca S. Muraoka-Cook et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Met, the hepatocyte growth factor receptor, localizes to the nucleus in cells at low density
Sharon Pozner-Moulis et al.
CANCER RESEARCH (2006)
Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage
Jaouhar Mourali et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
c-Met ectodomain shedding rate correlates with malignant potential
Gagani Athauda et al.
CLINICAL CANCER RESEARCH (2006)
Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells
Phillip C. C. Liu et al.
CANCER BIOLOGY & THERAPY (2006)
Selective inhibition of ADAM metalloproteases blocks HER-2 extracellular domain (ECD) cleavage and potentiates the anti-tumor effects of trastuzumab
Xiangdong Liu et al.
CANCER BIOLOGY & THERAPY (2006)
Metalloproteinase/presenilin 1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling
A Georgakopoulos et al.
EMBO JOURNAL (2006)
Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1 (Withdrawn Publication. See vol. 298, 2021)
J Cai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth
JA Maatta et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Adam meets Eph:: An ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans
PW Janes et al.
CELL (2005)
Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin
C Moog-Lutz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
ERK-mediated phosphorylation of Thr735 in TNFα-converting enzyme and its potential role in TACE protein trafficking
SM Soond et al.
JOURNAL OF CELL SCIENCE (2005)
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
U Sahin et al.
JOURNAL OF CELL BIOLOGY (2004)
Tumor necrosis factor-α-converting enzyme controls surface expression of c-kit and survival of embryonic stem cell-derived mast cells
AC Cruz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage
D Tulasne et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Phorbol 12-myristate 13-acetate-induced release of the colony-stimulating factor 1 receptor cytoplasmic domain into the cytosol involves two separate cleavage events
K Wilhelmsen et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Ectodomain cleavage of ErbB-4 - Characterization of the cleavage site and m80 fragment
QC Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6
E Trivier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor α-converting enzyme at threonine 735:: A potential role in regulated shedding
E Díaz-Rodríguez et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Tumor necrosis factor-α converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability
SW Sunnarborg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ligand-induced shedding of discoidin domain receptor 1
WF Vogel
FEBS LETTERS (2002)
Metalloprotease-dependent protransforming growth factor-α ectodomain shedding in the absence of tumor necrosis factor-α-converting enzyme
A Merlos-Suárez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
γ-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
CY Ni et al.
SCIENCE (2001)
Regulated cleavage of a contact-mediated axon repellent
M Hattori et al.
SCIENCE (2000)
The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease
MC Bordeaux et al.
EMBO JOURNAL (2000)
Tumor necrosis factor-α-converting enzyme is required for cleavage of erbB4/HER4
C Rio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)