4.7 Article

Multiscale Structural Elucidation of Peptide Nanotubes by X-Ray Scattering Methods

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2021.654339

关键词

peptide self-assembly; peptide nanotubes; peptide nanoribbons; X-ray scattering; SAXS

资金

  1. ESRF
  2. Knut and Alice Wallenberg Foundation [KAW 2014.0052]

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This review explores the structural investigations of self-assembled peptide nanotubes using X-ray scattering techniques. Compared to electron microscopy, scattering methods allow for studies of nanotubes in solution under the right physicochemical conditions and probe their formation mechanisms. Additionally, a combination of X-ray scattering methods enables the elucidation of structural organization from the molecular scale to the nanotube dimension.
This mini-review presents the structural investigations of the self-assembled peptide nanotubes using X-ray scattering techniques. As compared to electron microscopy, scattering methods enable studies of nanotubes in solution under the appropriate physicochemical conditions and probe their formation mechanism. In addition, a combination of X-ray scattering methods allow the elucidation of structural organization from the molecular scale to the dimension of nanotubes.

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