期刊
WORLD JOURNAL OF CLINICAL CASES
卷 9, 期 11, 页码 2419-2432出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.12998/wjcc.v9.i11.2419
关键词
Hepatocellular carcinoma; Portal hypertension; Radical laparoscopic treatment
Laparoscopic technique is effective in treating hepatocellular carcinoma with portal hypertension. Both short- and long-term prognosis of HCC patients after laparoscopic liver resection show no statistical difference, regardless of whether they suffer from PHT. Laparoscopic treatment has superior short- and long-term prognostic outcomes compared to non-laparoscopic treatment, and offers long-term prognostic advantage compared to laparoscopic radiofrequency ablation.
The laparoscopic technique is clinically effective in treating hepatocellular carcinoma (HCC) with portal hypertension (PHT). However, existing studies lack systematic arrangement and induction. Here, we review the latest research advancement in laparoscopic technique for treatment of HCC with PHT, based on published literature and our single-institution experience. Our single-center experience reveals no statistical difference in both short- and long-term prognosis of HCC patients after laparoscopic liver resection (LLR), regardless of whether they suffer from PHT, which is consistent with previous studies on the use of LLR for HCC with PHT. Retrieval outcomes indicate existence of short- and long-term prognostic superiority, following laparoscopic treatment, relative to non-laparoscopic treatment. Besides that, LLR offers long-term prognostic advantage compared to laparoscopic radiofrequency ablation. In addition, we review the previous literature and propose corresponding perspectives on the therapy of hypersplenism, the utilization of Pringle maneuver, and the adoption of anatomical hepatectomy during radical laparoscopic treatment. HCC with PHT is not the forbidden zone of radical laparoscopic treatment. However, patients' preoperative liver function should be adequately estimated.
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