期刊
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
卷 14, 期 -, 页码 1817-1821出版社
DOVE MEDICAL PRESS LTD
DOI: 10.2147/DMSO.S300015
关键词
polycystic ovary syndrome; Hashimoto's thyroiditis; insulin resistance; oral glucose tolerance test
资金
- Guangdong Provincial Science and Technology Department Research Fund Project [2017ZC0284]
The study found that PCOS patients with HT have higher levels of insulin secretion and IR, as well as relatively lower thyroid function. It is suggested that thyroid function and autoimmune status should be evaluated in clinical practice for patients with PCOS.
Objective: The incidence of Hashimoto's thyroiditis (HT) in patients with polycystic ovary syndrome (PCOS) is significantly higher than in normal controls, and there is a risk of more severe metabolic symptoms when the two diseases occur together. This study compares insulin secretion, insulin resistance (IR) and thyroid function in patients with PCOS with and without HT. Methods: A total of 164 patients (52 patients with HT (HT+) and 112 patients without HT diagnosed PCOS at our hospital were enrolled for testing of oral glucose tolerance, insulin release, thyroid function, the presence of thyroglobulin and thyroid peroxidase antibodies, and blood lipid levels. Results: Patients with PCOS and HT had higher insulin secretion and IR levels than those without HT, while free thyroxine and thyrotropin levels were significantly lower. The ratio of free thyroxine to thyrotropin was higher in patients with HT. Conclusion: HT may related with IR and relatively low thyroid function in patients with PCOS. Thus, thyroid function and autoimmune status in patients with PCOS should be evaluated in clinical practice.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据