4.7 Article

An altered microbiota pattern precedes Type 2 diabetes mellitus development: From the CORDIOPREV study

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Summary: Our study identified core gut microbial features associated with type 2 diabetes risk and future glucose increment using an interpretable machine learning framework. We also confirmed the relationship between these features and type 2 diabetes through human fecal sample transplantation to germ-free mice. Additionally, we found body fat distribution to be a key factor modulating the gut microbiome-type 2 diabetes relationship.

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