4.6 Review

Reporters of Cancer Stem Cells as a Tool for Drug Discovery

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Oncology

Immunotherapy: A Potential Approach to Targeting Cancer Stem Cells

Wenjun Wang et al.

Summary: CSCs, resistant to traditional therapies, play a central role in tumor recurrence and drug resistance, making them important targets in cancer immunotherapy. Emerging immunotherapies that selectively target CSCs could offer novel therapeutic approaches and combinations for treatment.

CURRENT CANCER DRUG TARGETS (2021)

Review Biochemistry & Molecular Biology

Marinne Natural Products as a Promising Source of Therappeutic Compounnds to Target Canncer Stem Cells

Catarina Vizetto-Duarte et al.

Summary: Cancer is the second leading cause of death in the world, and cancer stem cells in tumors are associated with treatment resistance and various processes in tumor development.

CURRENT MEDICINAL CHEMISTRY (2021)

Article Pharmacology & Pharmacy

The nicotinamide phosphoribosyltransferase antagonist FK866 inhibits growth of prostate tumour spheroids and increases doxorubicin retention without changes in drug transporter and cancer stem cell protein expression

Heinrich Sauer et al.

Summary: The NAMPT inhibitor FK866 inhibits prostate cancer cell proliferation by interfering with energy metabolism and drug efflux transporters.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2021)

Article Oncology

CDK1 promotes the stemness of lung cancer cells through interacting with Sox2

Z. Huang et al.

Summary: This study reveals a novel CDK1/Sox2 axis responsible for maintaining the stemness of lung cancer cells, which affects chemotherapeutic sensitivity.

CLINICAL & TRANSLATIONAL ONCOLOGY (2021)

Review Pharmacology & Pharmacy

Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

Ashish Ranjan Dwivedi et al.

CURRENT DRUG TARGETS (2020)

Article Medicine, Research & Experimental

Cancer Stem Cells and Epithelial-to-Mesenchymal Transition in Cancer Metastasis

Toni Celia-Terrassa et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2020)

Article Biochemistry & Molecular Biology

A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells

Branavan Manoranjan et al.

ONCOGENE (2020)

Article Pharmacology & Pharmacy

Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells

Daniella Kovacsics et al.

BIOCHEMICAL PHARMACOLOGY (2020)

Review Oncology

Drug repurposing towards targeting cancer stem cells in pediatric brain tumors

Hisham F. Bahmad et al.

CANCER AND METASTASIS REVIEWS (2020)

Review Biochemistry & Molecular Biology

Heterogeneity of Circulating Tumor Cells in Breast Cancer: Identifying Metastatic Seeds

Maxim E. Menyailo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Pharmacology & Pharmacy

Eradicating the Roots: Advanced Therapeutic Approaches Targeting Breast Cancer Stem Cells

Lili He et al.

CURRENT PHARMACEUTICAL DESIGN (2020)

Article Oncology

Hypoxia and cancer related pathology

Qiuxia Xiong et al.

CANCER LETTERS (2020)

Article Biochemistry & Molecular Biology

Characteristics of CD133-Sustained Chemoresistant Cancer Stem-Like Cells in Human Ovarian Carcinoma

Chao Lien Liu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell Biology

SOX2 in cancer stemness: tumor malignancy and therapeutic potentials

Mahfuz Al Mamun et al.

JOURNAL OF MOLECULAR CELL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Targeting cancer stem cell pathways for cancer therapy

Liqun Yang et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Review Oncology

Role of Microenvironment on the Fate of Disseminating Cancer Stem Cells

Vincenzo Ingangi et al.

FRONTIERS IN ONCOLOGY (2019)

Article Cell & Tissue Engineering

Oct4 Gene Expression in Primary Colorectal Cancer Promotes Liver Metastasis

Shiki Fujino et al.

STEM CELLS INTERNATIONAL (2019)

Article Biotechnology & Applied Microbiology

Effect of overexpression of Oct4 and Sox2 genes on the biological and oncological characteristics of gastric cancer cells

Borong Chen et al.

ONCOTARGETS AND THERAPY (2019)

Article Oncology

The cell of origin and the leukemia stem cell in acute myeloid leukemia

Martin Chopra et al.

GENES CHROMOSOMES & CANCER (2019)

Review Cell Biology

Cancer Stem Cells and Targeting Strategies

Luisa Barbato et al.

Review Cell & Tissue Engineering

Targeting Cancer Stemness in the Clinic: From Hype to Hope

Caner Saygin et al.

CELL STEM CELL (2019)

Article Medicine, Research & Experimental

Prostate Stem Cells and Cancer Stem Cells

Jia J. Li et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2019)

Article Cell Biology

Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression

Fang Wei et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

Article Pharmacology & Pharmacy

Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity

Rachel J. Eclov et al.

DRUG METABOLISM AND DISPOSITION (2018)

Article Multidisciplinary Sciences

STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion

Jung-Mao Hsu et al.

NATURE COMMUNICATIONS (2018)

Article Reproductive Biology

Characterization of stem cell and cancer stem cell populations in ovary and ovarian tumors

Seema C. Parte et al.

JOURNAL OF OVARIAN RESEARCH (2018)

Article Biochemistry & Molecular Biology

IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer

Dong Wang et al.

CELL DEATH AND DIFFERENTIATION (2018)

Article Oncology

The Efflux Transporter ABCG2 Maintains Prostate Stem Cells

Neha G. Sabnis et al.

MOLECULAR CANCER RESEARCH (2017)

Article Biochemistry & Molecular Biology

NANOG Expression as a Responsive Biomarker during Treatment with Hedgehog Signal Inhibitor in Acute Myeloid Leukemia

Seiji Kakiuchi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Oncology

Therapeutic strategies against cancer stem cells in human colorectal cancer

Magdalena Szarynska et al.

ONCOLOGY LETTERS (2017)

Editorial Material Oncology

Tumor-initiating CD49f cells are a hallmark of chemoresistant triple negative breast cancer

Jorge Gomez-Miragaya et al.

MOLECULAR & CELLULAR ONCOLOGY (2017)

Article Medicine, General & Internal

Silencing expression of the NANOG gene and changes in migration and metastasis of urinary bladder cancer cells

Natalia Gawlik-Rzemieniewska et al.

ARCHIVES OF MEDICAL SCIENCE (2016)

Review Cell Biology

Distinctive properties of metastasis-initiating cells

Toni Celia-Terrassa et al.

GENES & DEVELOPMENT (2016)

Article Biochemistry & Molecular Biology

Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines

Radoslaw Januchowski et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)

Article Oncology

Aldehyde dehydrogenase 1A1 in stem cells and cancer

Hiroyuki Tomita et al.

ONCOTARGET (2016)

Article Oncology

Cisplatin induces stemness in ovarian cancer

Andrew Wiechert et al.

ONCOTARGET (2016)

Review Chemistry, Medicinal

Existing drugs and their application in drug discovery targeting cancer stem cells

Junfang Lv et al.

ARCHIVES OF PHARMACAL RESEARCH (2015)

Article Nanoscience & Nanotechnology

Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells

Petra Gener et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

Article Cell & Tissue Engineering

A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells

Binwu Tang et al.

STEM CELL REPORTS (2015)

Article Multidisciplinary Sciences

SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma

Soufiane Boumahdi et al.

NATURE (2014)

Letter Oncology

Hypoxia promotes stem cell-like phenotype in multiple myeloma cells

B. Muz et al.

BLOOD CANCER JOURNAL (2014)

Review Oncology

SOX2 and cancer: current research and its implications in the clinic

Kasia Weina et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2014)

Article Oncology

A Novel Model of Dormancy for Bone Metastatic Breast Cancer Cells

Rebecca Marlow et al.

CANCER RESEARCH (2013)

Article Oncology

Prognostication of OCT4 isoform expression in prostate cancer

Marina Franca de Resende et al.

TUMOR BIOLOGY (2013)

Article Pharmacology & Pharmacy

Induction of Multidrug Resistance Transporter ABCG2 by Prolactin in Human Breast Cancer Cells

Alex Man Lai Wu et al.

MOLECULAR PHARMACOLOGY (2013)

Review Pharmacology & Pharmacy

Molecular Pharmacology of ABCG2 and Its Role in Chemoresistance

Alexandra E. Stacy et al.

MOLECULAR PHARMACOLOGY (2013)

Review Cell & Tissue Engineering

Cancer Stem Cells: Current Status and Evolving Complexities

Jane E. Visvader et al.

CELL STEM CELL (2012)

Article Biochemistry & Molecular Biology

CD133+EpCAM+ Phenotype Possesses More Characteristics of Tumor Initiating Cells in Hepatocellular Carcinoma Huh7 Cells

Yi Chen et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)

Article Biochemistry & Molecular Biology

Evaluation of the Adenocarcinoma-Associated Gene AGR2 and the Intestinal Stem Cell Marker LGR5 as Biomarkers in Colorectal Cancer

Manuel Valladares-Ayerbes et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)

Article Cell & Tissue Engineering

A novel variant of Oct3/4 gene in mouse embryonic stem cells

Chang-long Guo et al.

STEM CELL RESEARCH (2012)

Article Multidisciplinary Sciences

Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy

Shyam A. Patel et al.

SCIENTIFIC REPORTS (2012)

Review Medicine, Research & Experimental

ABCG2: A potential marker of stem cells and novel target in stern cell and cancer therapy

Xi-wei Ding et al.

LIFE SCIENCES (2010)

Article Multidisciplinary Sciences

Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like Properties

Elaine Lai-Han Leung et al.

PLOS ONE (2010)

Article Hematology

Circulating clonotypic B cells in classic Hodgkin lymphoma

Richard J. Jones et al.

Article Oncology

Aldehyde Dehydrogenase 1 Is a Tumor Stem Cell-Associated Marker in Lung Cancer

Feng Jiang et al.

MOLECULAR CANCER RESEARCH (2009)

Article Oncology

Significance of CD90+ cancer stem cells in human liver cancer

Zhen Fan Yang et al.

CANCER CELL (2008)

Article Biochemistry & Molecular Biology

The epithelial-mesenchymal transition generates cells with properties of stem cells

Sendurai A. Mani et al.

Review Biochemistry & Molecular Biology

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily

Satori A. Marchitti et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)

Article Cell & Tissue Engineering

Absence of OCT4 expression in somatic tumor cell lines

Tobias Cantz et al.

STEM CELLS (2008)

Article Biochemistry & Molecular Biology

Identification and expansion of the tumorigenic lung cancer stem cell population

A. Eramo et al.

CELL DEATH AND DIFFERENTIATION (2008)

Review Biochemistry & Molecular Biology

ABCG2: structure, function and role in drug response

Orsolya Polgar et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)

Article Oncology

Identification of pancreatic cancer stem cells

Chenwei Li et al.

CANCER RESEARCH (2007)

Article Multidisciplinary Sciences

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

Catherine A. O'Brien et al.

NATURE (2007)

Article Multidisciplinary Sciences

Identification and expansion of human colon-cancer-initiating cells

Lucia Ricci-Vitiani et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia

A Castor et al.

NATURE MEDICINE (2005)

Article Multidisciplinary Sciences

Identification of human brain tumour initiating cells

SK Singh et al.

NATURE (2004)