4.6 Review

Radiotherapy in the Era of Immunotherapy With a Focus on Non-Small-Cell Lung Cancer: Time to Revisit Ancient Dogmas?

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Proton therapy reduces the likelihood of high-grade radiation-induced lymphopenia in glioblastoma patients: phase II randomized study of protons vs photons

Radhe Mohan et al.

Summary: This study revealed that the incidence of G3+L was lower in patients with GBM treated with PT compared to XRT. Being female, baseline ALC, and whole-brain V20 were identified as the strongest predictors of G3+L.

NEURO-ONCOLOGY (2021)

Article Oncology

Randomized Phase II Trial of Nivolumab With Stereotactic Body Radiotherapy Versus Nivolumab Alone in Metastatic Head and Neck Squamous Cell Carcinoma

Sean McBride et al.

Summary: The study compared the efficacy of nivolumab alone versus nivolumab plus SBRT in treating patients with metastatic HNSCC, and found that the addition of SBRT did not improve treatment response in unselected patients.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Article Biochemistry & Molecular Biology

Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination

Jiali Yu et al.

Summary: Liver metastases diminish the efficacy of immunotherapy by siphoning activated CD8(+) T cells from systemic circulation, creating systemic immune desert. Combining liver-directed radiotherapy with immunotherapy can promote systemic antitumor immunity.

NATURE MEDICINE (2021)

Article Oncology

A Multi-institutional Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Patients With Medulloblastoma

Kevin X. Liu et al.

Summary: This study aimed to investigate the hematologic effects of craniospinal irradiation in pediatric patients with medulloblastoma using proton or photon therapy. The results showed that patients receiving proton therapy experienced significantly decreased hematologic toxicity compared to those receiving photon therapy.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2021)

Article Oncology

Progression-Free and Overall Survival for Concurrent Nivolumab With Standard Concurrent Chemoradiotherapy in Locally Advanced Stage IIIA-B NSCLC: Results From the European Thoracic Oncology Platform NICOLAS Phase II Trial (European Thoracic Oncology Platform 6-14)

Solange Peters et al.

Summary: The NICOLAS study evaluated the safety and efficacy of adding nivolumab to standard definitive concurrent chemoradiotherapy in stage III NSCLC patients. The 1-year progression-free survival rate was 53.7% and the median overall survival was 38.8 months. Patients with stage IIIA disease had a significantly higher survival rate compared to those with stage IIIB disease.

JOURNAL OF THORACIC ONCOLOGY (2021)

Letter Oncology

FLASH-radiotherapy: A new perspective in immunotherapy era?

Melek Tugce Yilmaz et al.

RADIOTHERAPY AND ONCOLOGY (2020)

Article Oncology

Radiotherapy-Related Lymphopenia Affects Overall Survival in Patients With Lung Cancer

Azadeh Abravan et al.

JOURNAL OF THORACIC ONCOLOGY (2020)

Article Oncology

Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy

Zachary S. Buchwald et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Article Oncology

The Impact of Radiation Therapy on Lymphocyte Count and Survival in Metastatic Cancer Patients Receiving PD-1 Immune Checkpoint Inhibitors

Luke R. G. Pike et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2019)

Article Oncology

Clinical translation of FLASH radiotherapy: Why and how?

Jean Bourhis et al.

RADIOTHERAPY AND ONCOLOGY (2019)

Review Oncology

Safety of stereotactic ablative body radiation for ultracentral stage I non-small cell lung cancer

Abraham J. G-Ching Wu

TRANSLATIONAL LUNG CANCER RESEARCH (2019)

Article Multidisciplinary Sciences

Tumor-reprogrammed resident T cells resist radiation to control tumors

Ainhoa Arina et al.

NATURE COMMUNICATIONS (2019)

Article Oncology

An Antitumor Immune Response Is Evoked by Partial-Volume Single-Dose Radiation in 2 Murine Models

Ela Markovsky et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2019)

Article Oncology

Time to abandon single-site irradiation for inducing abscopal effects

Eric D. Brooks et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Article Oncology

Radiation-related Lymphopenia after Pelvic Nodal Irradiation for Prostate Cancer

Michael D. Schad et al.

ADVANCES IN RADIATION ONCOLOGY (2019)

Review Oncology

A systematic review of the influence of radiation-induced lymphopenia on survival outcomes in solid tumors

Bhanu Prasad Venkatesulu et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2018)

Review Oncology

Total body irradiation in allogeneic bone marrow transplantation conditioning regimens: A review

Adrien Paix et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2018)

Article Oncology

Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site

Heather M. McGee et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)

Article Oncology

Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs

Julie M. Diamond et al.

CANCER IMMUNOLOGY RESEARCH (2018)

Article Medicine, General & Internal

Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC

S. J. Antonia et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Biochemistry & Molecular Biology

Radiotherapy induces responses of lung cancer to CTLA-4 blockade

Silvia C. Formenti et al.

NATURE MEDICINE (2018)

Article Oncology

Radiation effects on antitumor immune responses: current perspectives and challenges

Thomas Walle et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)

Review Oncology

Radiotherapy combination opportunities leveraging immunity for the next oncology practice

Fernanda G. Herrera et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2017)

Meeting Abstract Oncology

The ADscopal Effect? Control of Partially Irradiated Versus Completely Irradiated Tumors on a Prospective Trial of Pembrolizumab and SBRT Per NRG-BR001

J. M. Lemons et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2017)

Article Oncology

Does Unintentional Splenic Radiation Predict Outcomes After Pancreatic Cancer Radiation Therapy?

Awalpreet S. Chadha et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2017)

Article Multidisciplinary Sciences

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

Alexander C. Huang et al.

NATURE (2017)

Article Multidisciplinary Sciences

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Claire Vanpouille-Box et al.

NATURE COMMUNICATIONS (2017)

Article Oncology

Clinical Features of Acquired Resistance to Anti-PD-1 Therapy in Advanced Melanoma

Daniel Y. Wang et al.

CANCER IMMUNOLOGY RESEARCH (2017)

Article Immunology

Barriers to Radiation-induced In Situ Tumor vaccination

Erik Wennerberg et al.

FRONTIERS IN IMMUNOLOGY (2017)

Article Medicine, General & Internal

Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy

A. M. M. Eggermont et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

Christina Twyman-Saint Victor et al.

NATURE (2015)

Review Immunology

Molecular and cellular insights into T cell exhaustion

E. John Wherry et al.

NATURE REVIEWS IMMUNOLOGY (2015)

Article Oncology

Lymphopenia Association With Gross Tumor Volume and Lung V5 and Its Effects on Non-Small Cell Lung Cancer Patient Outcomes

Chad Tang et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2014)

Article Medicine, Research & Experimental

Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice

Liufu Deng et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Immunology

Histone Deacetylation Critically Determines T Cell Subset Radiosensitivity

Jason L. Pugh et al.

JOURNAL OF IMMUNOLOGY (2014)

Article Oncology

Intensity-Modulated Radiotherapy for Lung Cancer: Current Status and Future Developments

Clara Chan et al.

JOURNAL OF THORACIC ONCOLOGY (2014)

Article Oncology

Treatment-related Lymphopenia in Patients With Stage III Non-Small-Cell Lung Cancer

Jian L. Campian et al.

CANCER INVESTIGATION (2013)

Article Oncology

Long-Term Clinical Outcome of Intensity-Modulated Radiotherapy for Inoperable Non-Small Cell Lung Cancer: The MD Anderson Experience

Zhi-Qin Jiang et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2012)

Review Oncology

Gating and tracking, 4D in thoracic tumours

D. Verellen et al.

CANCER RADIOTHERAPIE (2010)

Article Biology

Gamma-Ray Resistance of Regulatory CD4+CD25+Foxp3+ T Cells in Mice

Yanyan Qu et al.

RADIATION RESEARCH (2010)

Article Oncology

Pulmonary toxicity following IMRT after extrapleural pneumonectomy for malignant pleural mesothelioma

Claus Andrup Kristensen et al.

RADIOTHERAPY AND ONCOLOGY (2009)

Article Immunology

Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells

Satoko Matsumura et al.

JOURNAL OF IMMUNOLOGY (2008)

Review Oncology

Hypoxic radiosensitization: Adored and ignored

Jens Overgaard

JOURNAL OF CLINICAL ONCOLOGY (2007)

Article Biochemistry & Molecular Biology

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apetoh et al.

NATURE MEDICINE (2007)

Article Immunology

Long-term immune dysfunction after radiotherapy to the head and neck area

EL Verastegui et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2003)

Article Immunology

Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo

JM Grayson et al.

JOURNAL OF IMMUNOLOGY (2002)