4.6 Review

Optimizing Transplant Approaches and Post-Transplant Strategies for Patients With Acute Myeloid Leukemia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Hematology

Venetoclax induces rapid elimination of NPM1 mutant measurable residual disease in combination with low-intensity chemotherapy in acute myeloid leukaemia

Ing S. Tiong et al.

Summary: This study demonstrates the significant efficacy of venetoclax-based therapy in reducing the risk of relapse in patients with persistent or rising NPM1(mut) MRD.

BRITISH JOURNAL OF HAEMATOLOGY (2021)

Article Hematology

Double unrelated umbilical cord blood vs HLA-haploidentical bone marrow transplantation: the BMT CTN 1101 trial

Ephraim J. Fuchs et al.

Summary: Results from two parallel phase 2 trials comparing unrelated umbilical cord blood transplantation and HLA-haploidentical bone marrow transplantation showed similar 2-year progression-free survival rates, but lower overall survival and higher nonrelapse mortality rates after umbilical cord blood transplantation compared to haploidentical bone marrow transplantation.
Article Biophysics

Impact of patient: donor HLA disparity on reduced-intensity-conditioned allogeneic stem cell transplants from HLA mismatched unrelated donors for AML: from the ALWP of the EBMT

J. Loke et al.

Summary: A study of 937 AML patients undergoing transplantation from a mismatched unrelated donor found that patient age, adverse karyotype, and CMV seropositivity were correlated with decreased LFS and OS. There was no significant difference in LFS or OS between patients transplanted from donors mismatched at different HLA loci, but HLA-A mismatched transplants were associated with higher rates of acute GVHD and NRM. Patient CMV seropositivity was linked to increased NRM and acute GVHD, as well as reduced LFS and OS.

BONE MARROW TRANSPLANTATION (2021)

Article Oncology

Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia

Charles Craddock et al.

Summary: The intensified RIC conditioning regimen, FLAMSA-Bu, did not improve outcomes for adults undergoing transplantation for high-risk AML or MDS, regardless of pretransplant MRD status. Pretransplant detectable MRD was associated with disease relapse, but acquisition of full donor T-cell chimerism improved overall survival.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Article Hematology

How I treat acute myeloid leukemia in the era of new drugs

Courtney D. DiNardo et al.

Review Hematology

Next-generation sequencing for measurable residual disease detection in acute myeloid leukaemia

Jack Ghannam et al.

BRITISH JOURNAL OF HAEMATOLOGY (2020)

Article Oncology

Composite GRFS and CRFS Outcomes After Adult Alternative Donor HCT

Rohtesh S. Mehta et al.

JOURNAL OF CLINICAL ONCOLOGY (2020)

Article Medicine, General & Internal

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

C. D. DiNardo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Multidisciplinary Sciences

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

Charles C. Bell et al.

NATURE COMMUNICATIONS (2019)

Review Biochemistry & Molecular Biology

Relapse of Acute Myeloid Leukemia after Allogeneic Stem Cell Transplantation: Prevention, Detection, and Treatment

Christina Rautenberg et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Oncology

Role of Donor Clonal Hematopoiesis in Allogeneic Hematopoietic Stem-Cell Transplantation

Mareike Frick et al.

JOURNAL OF CLINICAL ONCOLOGY (2019)

Article Education, Scientific Disciplines

The growing landscape of FLT3 inhibition in AML

Catherine C. Smith

Hematology-American Society of Hematology Education Program (2019)

Article Hematology

Development of an Unrelated Donor Selection Score Predictive of Survival after HCT: Donor Age Matters Most

Bronwen E. Shaw et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2018)

Article Hematology

Early Post-Transplant Minimal Residual Disease Assessment Improves Risk Stratification in Acute Myeloid Leukemia

Mithun Vinod Shah et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2018)

Article Hematology

CC-486 Maintenance after Stem Cell Transplantation in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndromes

Marcos de Lima et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2018)

Article Medicine, General & Internal

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

C. D. DiNardo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Molecular Minimal Residual Disease in Acute Myeloid Leukemia

M. Jongen-Lavrencic et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Mutation Clearance after Transplantation for Myelodysplastic Syndrome

E. J. Duncavage et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Hematology

Acute myeloid leukemia: 2019 update on risk-stratification and management

Elihu H. Estey

AMERICAN JOURNAL OF HEMATOLOGY (2018)

Article Medicine, General & Internal

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

J. Grinfeld et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation

F. M. Marty et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

R. M. Stone et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Assessment of Minimal Residual Disease in Standard-Risk AML

A. Ivey et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Elli Papaemmanuil et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the US Registry

Loren Gragert et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Biophysics

The EBMT risk score

A. Gratwohl

BONE MARROW TRANSPLANTATION (2012)

Review Oncology

Monitoring Minimal Residual Disease in Acute Myeloid Leukemia: Ready for Prime Time?

Farhad Ravandi et al.

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2012)

Review Hematology

Independent prognostic variables in acute myeloid leukaemia

Matthew L. Smith et al.

BLOOD REVIEWS (2011)

Article Hematology

Cord Blood Transplantation from Unrelated Donors in Adults with High-Risk Acute Myeloid Leukemia

Jaime Sanz et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2010)

Article Medicine, General & Internal

Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation.

Ted A. Gooley et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Biochemistry & Molecular Biology

Hedgehog signaling maintains chemoresistance in myeloid leukemic cells

K. C. S. Queiroz et al.

ONCOGENE (2010)

Article Hematology

Defining the Intensity of Conditioning Regimens: Working Definitions

Andrea Bacigalupo et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2009)

Article Medicine, General & Internal

Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors.

MJ Laughlin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)