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ING3 protein expression profiling in normal human tissues suggest its role in cellular growth and self-renewal
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Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response
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NATURE (2006)
Targeted disruption of the mouse ing1 locus results in reduced body size, hypersensitivity to radiation and elevated incidence of lymphomas
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ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation
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MOLECULAR CELL (2006)
Multiple variants of the ING1 and ING2 tumor suppressors are differentially expressed and thyroid hormone-responsive in Xenopus laevis
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ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation
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Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair
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The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF)
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The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
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NATURE (2004)
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans
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MOLECULAR AND CELLULAR BIOLOGY (2004)
Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Biological functions of the ING family tumor suppressors
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CELLULAR AND MOLECULAR LIFE SCIENCES (2004)
ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells
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FEBS LETTERS (2004)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
ORC, MCM, and histone hyperacetylation at the Kaposi's sarcoma-associated herpesvirus latent replication origin
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Role of the histone acetyl transferase Tip60 in the p53 pathway
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor
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CELL (2003)
Opposite role of yeast ING family members in p53-dependent transcriptional activation
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MOLECULAR AND CELLULAR BIOLOGY (2002)
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MOLECULAR AND CELLULAR BIOLOGY (2002)
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Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression
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MOLECULAR AND CELLULAR BIOLOGY (2001)
DNA damage-inducible gene p331NG2 negatively regulates cell proliferation through acetylation of p53
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Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complex
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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
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