4.6 Review

Targeting the Metabolic Adaptation of Metastatic Cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Cysteine and Folate Metabolism Are Targetable Vulnerabilities of Metastatic Colorectal Cancer

Josep Tarrago-Celada et al.

Summary: This study identified cystine uptake and folate metabolism as potential therapeutic targets against metastatic colorectal cancer, highlighting the importance of redox homeostasis in the metastatic cell lines.

CANCERS (2021)

Review Cell Biology

Metabolic pathways regulating colorectal cancer initiation and progression

Sofia La Vecchia et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)

Review Endocrinology & Metabolism

Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion

Peter Kreuzaler et al.

MOLECULAR METABOLISM (2020)

Article Biochemistry & Molecular Biology

Immobilization of L-Asparaginase on Magnetic Nanoparticles for Cancer Treatment

Hande Orhan et al.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2020)

Review Oncology

Defining a metabolic landscape of tumours: genome meets metabolism

Chandan Seth Nanda et al.

BRITISH JOURNAL OF CANCER (2020)

Review Oncology

Reprogramming of fatty acid metabolism in cancer

Nikos Koundouros et al.

BRITISH JOURNAL OF CANCER (2020)

Review Multidisciplinary Sciences

Mitochondrial TCA cycle metabolites control physiology and disease

Inmaculada Martinez-Reyes et al.

NATURE COMMUNICATIONS (2020)

Review Oncology

Pyruvate Kinase M2 and Cancer: The Role of PKM2 in Promoting Tumorigenesis

Kulsoom Zahra et al.

FRONTIERS IN ONCOLOGY (2020)

Article Oncology

Metabolic models predict bacterial passengers in colorectal cancer

Daniel R. Garza et al.

CANCER & METABOLISM (2020)

Article Endocrinology & Metabolism

Identifying strategies to target the metabolic flexibility of tumours

Andres Mendez-Lucas et al.

NATURE METABOLISM (2020)

Review Biochemistry & Molecular Biology

Changes in lipids composition and metabolism in colorectal cancer: a review

Alicja Pakiet et al.

LIPIDS IN HEALTH AND DISEASE (2019)

Article Multidisciplinary Sciences

Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

Ilaria Elia et al.

NATURE (2019)

Article Multidisciplinary Sciences

Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation

Choong-kun Lee et al.

SCIENCE (2019)

Review Oncology

Interactions in the (Pre)metastatic Niche Support Metastasis Formation

Ginevra Doglioni et al.

FRONTIERS IN ONCOLOGY (2019)

Review Oncology

Mutant Isocitrate Dehydrogenase Inhibitors as Targeted Cancer Therapeutics

Danielle Golub et al.

FRONTIERS IN ONCOLOGY (2019)

Article Pharmacology & Pharmacy

Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors

En-Qin Li et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

Review Endocrinology & Metabolism

The Potential Effect of Metformin on Cancer: An Umbrella Review

Hong Yu et al.

FRONTIERS IN ENDOCRINOLOGY (2019)

Review Oncology

Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects

Muhamad Noor Alfarizal Kamarudin et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Review Biotechnology & Applied Microbiology

Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality Profiles

Larissa Pereira Brumano et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)

Article Medicine, Research & Experimental

Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit

Chih-Chia Kuo et al.

THERANOSTICS (2019)

Article Cell Biology

As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid

Natalya N. Pavlova et al.

CELL METABOLISM (2018)

Article Multidisciplinary Sciences

Asparagine bioavailability governs metastasis in a model of breast cancer

Simon R. V. Knott et al.

NATURE (2018)

Review Cell Biology

Metabolic Hallmarks of Metastasis Formation

Ilaria Elia et al.

TRENDS IN CELL BIOLOGY (2018)

Review Oncology

Colorectal Cancer and Metabolism

Rachel E. Brown et al.

CURRENT COLORECTAL CANCER REPORTS (2018)

Article Multidisciplinary Sciences

Targeting metastasis-initiating cells through the fatty acid receptor CD36

Gloria Pascual et al.

NATURE (2017)

Review Biochemistry & Molecular Biology

Emerging roles of lipid metabolism in cancer metastasis

Xiangjian Luo et al.

MOLECULAR CANCER (2017)

Article Multidisciplinary Sciences

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

Oliver D. K. Maddocks et al.

NATURE (2017)

Article Multidisciplinary Sciences

Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC

Kiyotoshi Satoh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases

Silvia Lemma et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)

Review Biochemistry & Molecular Biology

Targeting Metabolism for Cancer Therapy

Alba Luengo et al.

CELL CHEMICAL BIOLOGY (2017)

Review Oncology

Hopefully devoted to Q: targeting glutamine addiction in cancer

Emma R. Still et al.

BRITISH JOURNAL OF CANCER (2017)

Article Biotechnology & Applied Microbiology

Differential Site-Based Expression of Pentose Phosphate Pathway-Related Proteins among Breast Cancer Metastases

Yoon Jin Cha et al.

DISEASE MARKERS (2017)

Article Biochemistry & Molecular Biology

Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity

Qian Wang et al.

CELL CHEMICAL BIOLOGY (2017)

Review Cell Biology

One-Carbon Metabolism in Health and Disease

Gregory S. Ducker et al.

CELL METABOLISM (2017)

Review Cell Biology

The Emerging Hallmarks of Cancer Metabolism

Natalya N. Pavlova et al.

CELL METABOLISM (2016)

Article Medicine, Research & Experimental

Role of mitochondrial dysfunction in cancer progression

Chia-Chi Hsu et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2016)

Article Cell Biology

Cancer metabolism at a glance

Alexei Vazquez et al.

JOURNAL OF CELL SCIENCE (2016)

Review Biochemistry & Molecular Biology

Mitochondria and Cancer

Wei-Xing Zong et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

A PGC1α-mediated transcriptional axis suppresses melanoma metastasis

Chi Luo et al.

NATURE (2016)

Article Cell Biology

The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

Veronica Torrano et al.

NATURE CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer

Masaaki Miyo et al.

SCIENTIFIC REPORTS (2016)

Review Oncology

Lipid metabolic reprogramming in cancer cells

S. Beloribi-Djefaflia et al.

ONCOGENESIS (2016)

Article Biochemistry & Molecular Biology

Extracellular Metabolic Energetics Can Promote Cancer Progression

Jia Min Loo et al.

Article Oncology

Metabolic Dependencies in RAS-Driven Cancers

Alec C. Kimmelman

CLINICAL CANCER RESEARCH (2015)

Article Medicine, Research & Experimental

ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis

Souvik Dey et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Medicine, Research & Experimental

Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients

Gaojie Liu et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Article Medicine, Research & Experimental

Metabolic signatures differentiate ovarian from colon cancer cell lines

Anna Halama et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Article Multidisciplinary Sciences

Oxidative stress inhibits distant metastasis by human melanoma cells

Elena Piskounova et al.

NATURE (2015)

Article Cell Biology

Antioxidants can increase melanoma metastasis in mice

Kristell Le Gal et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Article Oncology

Overcoming 5-Fu Resistance of Colon Cells through Inhibition of Glut1 by the Specific Inhibitor WZB117

Wei Liu et al.

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2014)

Article Biochemistry & Molecular Biology

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Tomoyuki Mashimo et al.

Article Biochemistry & Molecular Biology

Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer

Kira T. Pate et al.

EMBO JOURNAL (2014)

Article Medicine, Research & Experimental

Site-specific metabolic phenotypes in metastatic breast cancer

Hye Min Kim et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2014)

Article Multidisciplinary Sciences

Human breast cancer metastases to the brain display GABAergic properties in the neural niche

Josh Neman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Cell Biology

A Mitochondrial Switch Promotes Tumor Metastasis

Paolo E. Porporato et al.

CELL REPORTS (2014)

Review Biochemistry & Molecular Biology

Anoikis molecular pathways and its role in cancer progression

Paolo Paoli et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)

Article Biochemistry & Molecular Biology

Succinate Dehydrogenase 5 (SDH5) Regulates Glycogen Synthase Kinase 3β-β-Catenin-mediated Lung Cancer Metastasis

Jun Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Oncology

The landscape of histone acetylation involved in epithelial-mesenchymal transition in lung cancer

Lin Zhang et al.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2013)

Article Biochemistry & Molecular Biology

Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)

Alexandra R. Grassian et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Review Oncology

Antimetabolites: Established cancer therapy

Manjul Tiwari

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS (2012)

Review Cell Biology

Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis

Dania Daye et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)

Article Oncology

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

Sirkku Pollari et al.

BREAST CANCER RESEARCH AND TREATMENT (2011)

Article Cell Biology

Novel invadopodia components revealed by differential proteomic analysis

Francesca Attanasio et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2011)

Article Cell Biology

Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation

Alexandra R. Grassian et al.

GENES & DEVELOPMENT (2011)

Article Biochemistry & Molecular Biology

Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial-Mesenchymal Transition

Min-Zu Wu et al.

MOLECULAR CELL (2011)

Article Multidisciplinary Sciences

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

Zachary T. Schafer et al.

NATURE (2009)

Article Multidisciplinary Sciences

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang et al.

NATURE (2009)

Review Oncology

Metastasis: from dissemination to organ-specific colonization

Don X. Nguyen et al.

NATURE REVIEWS CANCER (2009)

Article Biochemistry & Molecular Biology

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells

Thomas McFate et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)