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注意:仅列出部分参考文献,下载原文获取全部文献信息。SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice
Veronica Moncho-Amor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
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The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
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ACTA NEUROPATHOLOGICA (2016)
mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance
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Epigenetic modulation of a miR-296-5p:HMGA1 axis regulates Sox2 expression and glioblastoma stem cells
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Targeting SOX2 as a Therapeutic Strategy in Glioblastoma
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Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter
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A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential
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Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression
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Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
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SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells
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The enhancement of neural stem cell survival and growth by coculturing with expanded sertoli cells in vitro
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p27Kip1 Directly Represses Sox2 during Embryonic Stem Cell Differentiation
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Sox2 expression in breast tumours and activation in breast cancer stem cells
O. Leis et al.
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Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile
Daniel Hagerstrand et al.
NEURO-ONCOLOGY (2011)
Genetic and Epigenetic Modifications of Sox2 Contribute to the Invasive Phenotype of Malignant Gliomas
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Sox2 regulatory region 2 sequence works as a DNA nuclear targeting sequence enhancing the efficiency of an exogenous gene expression in ES cells
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
SOX2 Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity
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STEM CELLS (2009)
Epigenetic modifications of SOX2 enhancers, SRR1 and SRR2, correlate with in vitro neural differentiation
Marianna Sikorska et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon
S Miyagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells
S Miyagi et al.
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Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex
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NUCLEIC ACIDS RESEARCH (2002)