期刊
JOURNAL OF CLINICAL MEDICINE
卷 10, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/jcm10081774
关键词
LED device; low-level laser therapy; rejuvenation; safety; thyroid gland
资金
- Korea Medical Device Development Fund - Korea government (the Ministry of Science and ICT) [202014X4502]
- Korea Medical Device Development Fund - Korea government (the Ministry of Trade, Industry and Evergy) [202014X4502]
- Korea Medical Device Development Fund - Korea government (the Ministry of Health & Welfare, Republic of Korea) [202014X4502]
- Korea Medical Device Development Fund - Korea government (the Ministry of Food and Drug Safety) [202014X4502]
Home-use LED devices are safe and effective for neck rejuvenation, with significant improvements in skin parameters. The use of LED devices did not show any significant adverse effects on the adjacent thyroid and parathyroid glands.
Home-use light-emitting diodes (LEDs) are attracting growing attention regarding their anti-aging effects. Although most previous studies on the use of LED devices as a form of low-level laser therapy reported no significant adverse events, questions regarding the safety of using a light source on secretory tissues have been raised. This study aimed to assess the safety and efficacy of a home-use LED device for neck skin rejuvenation, particularly regarding its effect on thyroid gland morphology and function. Thyroid function tests and ultrasonographic analyses showed no significant changes after 16 weeks of LED use. Evaluation using the Lemperle wrinkle scale and global improvement scales by both investigators and subjects showed significant improvement after 16 weeks of daily application, as well as 8 weeks after discontinuation. Biophysical parameters, such as hydration, elasticity, and density, also showed significant improvements. Hence, the long-term use of the LED device was safe and effective for neck rejuvenation, and showed no significant side effects on the adjacent thyroid and parathyroid glands.
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