Obesity as the 21st Century's major disease: The role of probiotics and prebiotics in prevention and treatment

Metabolic disorders such as obesity are a serious health issue causing various health impairments, including cardiovascular diseases, type-2 diabetes, musculoskeletal disorders and several types of cancer. Recent studies have shown that there is a correlation between gut microbiota and metabolic disorders. It was revealed that differences in composition of intestinal microbiota are noticeable between lean and obese subjects. The gut microbes impact the metabolism of the host as well as immunological and endocrine systems. These microorganisms can regulate gene expression which can influence the host's ability to store or obtain energy from edible products. Therefore, it is essential to maintain proper balance of intestinal microbiota, by proper diet and usage of probiotics and prebiotics, in order to keep the host's health intact. The impact of gastrointestinal microbes, probiotics, and prebiotics on several processes leading to abovementioned metabolic disorder is further discussed giving a clear overview on the subject.

Automated summary

Research indicates a correlation between gut microbiota and metabolic disorders, with noticeable differences in composition between lean and obese individuals. Maintaining a proper balance of intestinal microbiota through proper diet and use of probiotics and prebiotics is crucial for preserving the host's health. The impact of gastrointestinal microbes, probiotics, and prebiotics on processes leading to metabolic disorders is further discussed for a clear overview.