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Gut-Based Strategies to Reduce Postprandial Glycaemia in Type 2 Diabetes

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FRONTIERS IN ENDOCRINOLOGY
卷 12, 期 -, 页码 -

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FRONTIERS MEDIA SA
DOI: 10.3389/fendo.2021.661877

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gastric emptying; type 2 diabetes; postprandial glucose (PPG); incretin hormones; GLP-1 receptor agonist

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Postprandial glycemic control is crucial for optimal management of type 2 diabetes, with the gastrointestinal tract playing a significant role. Various strategies, such as slowing gastric emptying and stimulating the incretin hormone GLP-1, have been proposed to modulate gastrointestinal function and improve postprandial glycaemia.
Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate gastrointestinal function, particularly by slowing gastric emptying and/or stimulating incretin hormone GLP-1, are summarized in this review.

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