4.6 Article

Possible Prosthetic Valve Endocarditis by Pandoraea pnomenusa and Specific Virulence Mechanisms

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INFECTION AND DRUG RESISTANCE
卷 14, 期 -, 页码 1319-1324

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DOVE MEDICAL PRESS LTD
DOI: 10.2147/IDR.S301138

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prosthetic valve endocarditis; central venous catheter; bacteremia; Pandoraea pnomenusa; biofilm formation; antibiotic resistance

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This study presents the first case of possible prosthetic valve endocarditis caused by Pandoraea spp. in a 37-year-old male injecting drug user with recurrent endocarditis. Biofilm formation and antibiotic resistance of the P. pnomenusa isolates from this patient were also investigated.
Bacteremia by Pandoraea spp. has rarely been described before. We report the first case of a P. pnomenusa possible prosthetic valve endocarditis, according to the modified Duke criteria, in a 37-year old male injecting drug user suffering from recurrent endocarditis. Furthermore, we demonstrate biofilm formation by the P. pnomenusa isolates of this patient and investigate antibiotic resistance.

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