4.6 Article

Genome-Wide Detection of Runs of Homozygosity in Laiwu Pigs Revealed by Sequencing Data

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Article Evolutionary Biology

Whole-genome SNP markers reveal conservation status, signatures of selection, and introgression in Chinese Laiwu pigs

Xiaopeng Wang et al.

Summary: The study found that the current population of Laiwu pigs has more genetic diversity than 18 years ago, possibly due to gene flow from European commercial breeds. Significant introgression of European haplotypes into Laiwu pigs is evident, with an average of 26.66% of genetic components originating from Europe. A family-based conservation strategy was proposed to reduce inbreeding depression in Laiwu pigs, and a list of candidate genes related to fat deposition, reproduction, and growth in Laiwu pigs was identified. Strong introgression from European pigs at the GPC6 locus was detected, likely contributing to improved growth performance in Laiwu pigs.

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