相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Macrophages and the maintenance of homeostasis
David M. Mosser et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses
Jennifer R. Brown et al.
AMERICAN JOURNAL OF HEMATOLOGY (2021)
Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion
Wenli Fang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration
Yanyun Zhao et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations
Di He et al.
ONCOGENE (2021)
Nucleic Acid Sensors and Programmed Cell Death
Jonathan Maelfait et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor
Jing-Yiing Wu et al.
MOLECULAR CELL (2020)
Bladder cancer cell-secreted exosomal miR-21 activates the PI3K/AKT pathway in macrophages to promote cancer progression
Fan Lin et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2020)
Randomized, Placebo-Controlled Clinical Trial Combining Pentoxifylline-Tocopherol and Clodronate in the Treatment of Radiation-Induced Plexopathy
Sylvie E. Delanian et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2020)
Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas
Reuben Moncada et al.
NATURE BIOTECHNOLOGY (2020)
CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
Joseph A. Flores-Toro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells
Jose Ignacio Gonzalez Solari et al.
BMC CANCER (2020)
Targeting macrophages: a novel avenue for cancer drug discovery
Sahana Kumar et al.
EXPERT OPINION ON DRUG DISCOVERY (2020)
Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis
Monica G. Mendoza-Rodriguez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Prognostic value of macrophage polarization markers in epithelial neoplasms and melanoma. A systematic review and meta-analysis
Alvaro Lopez-Janeiro et al.
MODERN PATHOLOGY (2020)
Low-Dose Metformin Reprograms the Tumor Immune Microenvironment in Human Esophageal Cancer: Results of a Phase II Clinical Trial
Shuhong Wang et al.
CLINICAL CANCER RESEARCH (2020)
Notch and TLR signaling coordinate monocyte cell fate and inflammation
Jaba Gamrekelashvili et al.
ELIFE (2020)
P2X7 Receptor Antagonism as a Potential Therapy in Amyotrophic Lateral Sclerosis
Cristina Ruiz-Ruiz et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)
M2-Like Tumor-Associated Macrophage-Targeted Codelivery of STAT6 Inhibitor and IKKβ siRNA Induces M2-to-M1 Repolarization for Cancer Immunotherapy with Low Immune Side Effects
Hong Xiao et al.
ACS CENTRAL SCIENCE (2020)
Bone marrow mesenchymal stem cells induce M2 microglia polarization through PDGF-AA/MANF signaling
Fan Yang et al.
WORLD JOURNAL OF STEM CELLS (2020)
Galectin-3 Stimulates Tyro3 Receptor Tyrosine Kinase and Erk Signalling, Cell Survival and Migration in Human Cancer Cells
Nour Al Kafri et al.
BIOMOLECULES (2020)
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression
Anna Fishbein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Poly-ICLC, a multi-functional immune modulator for treating cancer
Hussein Sultan et al.
SEMINARS IN IMMUNOLOGY (2020)
Hypoxia Correlates With Poor Survival and M2 Macrophage Infiltration in Colorectal Cancer
Lina Qi et al.
FRONTIERS IN ONCOLOGY (2020)
Dasatinib Inhibits Lung Cancer Cell Growth and Patient Derived Tumor Growth in Mice by Targeting LIMK1
Man Zhang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy
Megan M. Tu et al.
COMMUNICATIONS BIOLOGY (2020)
Beta-1,6 glucan converts tumor-associated macrophages into an M1-like phenotype
Hairong Cheng et al.
CARBOHYDRATE POLYMERS (2020)
Immunological Differences Between Immune-Rich Estrogen Receptor-Positive and Immune-Rich Triple-Negative Breast Cancers
Tess O'Meara et al.
JCO PRECISION ONCOLOGY (2020)
Indoleamine 2,3-Dioxygenase Regulates Macrophage Recruitment, Polarization and Phagocytosis in Aspergillus Fumigatus Keratitis
Nan Jiang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2020)
Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3 beta/beta-catenin pathway
Shu-Jie Zhao et al.
THERANOSTICS (2020)
ATP in the tumour microenvironment drives expression of nfP2X7, a key mediator of cancer cell survival
S. M. Gilbert et al.
ONCOGENE (2019)
Anti-PD-L1 Treatment Results in Functional Remodeling of the Macrophage Compartment
Huizhong Xiong et al.
CANCER RESEARCH (2019)
Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer
Canan Kasikara et al.
CANCER RESEARCH (2019)
MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation
Chihiro Nishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer
Yueh-Shan Weng et al.
MOLECULAR CANCER (2019)
Neoantigen-directed immune escape in lung cancer evolution
Rachel Rosenthal et al.
NATURE (2019)
Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer
Rongsheng Zhang et al.
CELL DEATH & DISEASE (2019)
Phase I study of emactuzumab single agent or in combination with paclitaxel in patients with advanced/metastatic solid tumors reveals depletion of immunosuppressive M2-like macrophages
C. A. Gomez-Roca et al.
ANNALS OF ONCOLOGY (2019)
Inflammatory Breast Cancer Promotes Development of M2 Tumor-Associated Macrophages and Cancer Mesenchymal Cells through a Complex Chemokine Network
Amanda Valeta-Magara et al.
CANCER RESEARCH (2019)
Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
Ivan Perrot et al.
CELL REPORTS (2019)
Connexin-43-dependent ATP release mediates macrophage activation during sepsis
Michel Dosch et al.
ELIFE (2019)
Dissecting intratumoral myeloid cell plasticity by single cell RNA-seq
Qianqian Song et al.
CANCER MEDICINE (2019)
Generation of monocyte-derived tumor-associated macrophages using tumor- conditioned media provides a novel method to study tumor-associated macrophages in vitro
Brooke Benner et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Estimation of immune cell content in tumor using single-cell RNA-seq reference data
Xiaoqing Yu et al.
BMC CANCER (2019)
Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial
William D. Tap et al.
LANCET (2019)
CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy
Amira A. Barkal et al.
NATURE (2019)
A Phase I Study of Binimetinib (MEK162) Combined with Pexidartinib (PLX3397) in Patients with Advanced Gastrointestinal Stromal Tumor
Evan Rosenbaum et al.
ONCOLOGIST (2019)
Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod
Mariya Rozenblit et al.
SCIENTIFIC REPORTS (2019)
Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRP&x251; axis
Hongcheng Yang et al.
CANCER MEDICINE (2019)
The Remarkable Plasticity of Macrophages: A Chance to Fight Cancer
Nadege Bercovici et al.
FRONTIERS IN IMMUNOLOGY (2019)
Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis
B. E. Sands et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti-PD-1 Therapy in Melanoma
Alisha Holtzhausen et al.
CANCER IMMUNOLOGY RESEARCH (2019)
Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo
Khatora S. Opperman et al.
NEOPLASIA (2019)
Prognostic value and clinicopathological roles of phenotypes of tumour-associated macrophages in colorectal cancer
Yamei Zhao et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2019)
Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction
Shixiang Wang et al.
ELIFE (2019)
Tumour-Secreted Protein S (ProS1) Activates a Tyro3-Erk Signalling Axis and Protects Cancer Cells from Apoptosis
Nour Al Kafri et al.
CANCERS (2019)
Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas
Pia S. Zeiner et al.
BRAIN PATHOLOGY (2019)
Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy
Laura A. Vitale et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2019)
Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan-Kynurenine-Aryl Hydrocarbon Axis
Brian W. Labadie et al.
CLINICAL CANCER RESEARCH (2019)
Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw
Weiwen Zhu et al.
FASEB JOURNAL (2019)
Autocrine VEGF signalling on M2 macrophages regulates PD-L1 expression for immunomodulation of T cells
Yin-Siew Lai et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
M2b macrophage polarization and its roles in diseases
Le-xun Wang et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2019)
The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment
Elena De Marchi et al.
ONCOGENE (2019)
Inherited NBN Mutations and Prostate Cancer Risk and Survival
Bogna Rusak et al.
CANCER RESEARCH AND TREATMENT (2019)
Phase I study of CpG ODN(K3), a novel toll-like receptor 9 agonist, for advanced lung cancer: Interim analyses of safety and immunity in subcutaneous injection cohort.
Tomoyuki Otsuka et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype
Simone Borgoni et al.
ONCOIMMUNOLOGY (2018)
Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer
Xianmin Mu et al.
CELL CYCLE (2018)
High-Fat Diet-Induced Inflammation Accelerates Prostate Cancer Growth via IL6 Signaling
Takuji Hayashi et al.
CLINICAL CANCER RESEARCH (2018)
Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression
David B. Gurevich et al.
EMBO JOURNAL (2018)
Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer
Karin Binnemars-Postma et al.
FASEB JOURNAL (2018)
Role of Human Macrophage Polarization in Inflammation during Infectious Diseases
Chiraz Atri et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Targeting Macrophages as a Potential Therapeutic Intervention: Impact on Inflammatory Diseases and Cancer
Mirco Ponzoni et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
被撤回的出版物: IL-6/STAT3 pathway intermediates M1/M2 macrophage polarization during the development of hepatocellular carcinoma (Retracted article. See vol. 123, pg. 1118, 2022)
Zi Yin et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response
Eric Ubil et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity
Curtis J. Perry et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity
Sabine Hoves et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance (vol 24, 21, 2018)
Mingzhu He et al.
MOLECULAR MEDICINE (2018)
Imatinib prevents lung cancer metastasis by inhibiting M2-like polarization of macrophages
Zhangting Yao et al.
PHARMACOLOGICAL RESEARCH (2018)
Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviors
Yang Yang et al.
CELL DEATH & DISEASE (2018)
Cell Death, Nucleic Acids, and Immunity Inflammation Beyond the Grave
Keith B. Elkon
ARTHRITIS & RHEUMATOLOGY (2018)
Toll-Like Receptors Drive Specific Patterns of Tolerance and Training on Restimulation of Macrophages
Suzanne K. Butcher et al.
FRONTIERS IN IMMUNOLOGY (2018)
Lacroferrin-Containing Immunocomplexes Drive the Conversion of Human Macrophages from M2-into M1-like phenotype
Chen-Hui Gao et al.
FRONTIERS IN IMMUNOLOGY (2018)
Use of PD-1 Targeting, Macrophage Infiltration, and IDO Pathway Activation in Sarcomas A Phase 2 Clinical Trial
Maud Toulmonde et al.
JAMA ONCOLOGY (2018)
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
Christopher B. Rodell et al.
NATURE BIOMEDICAL ENGINEERING (2018)
The lack of PI3Kγ favors M1 macrophage polarization and does not prevent kidney diseases progression
Mariane T. Amano et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
Phase II open-label, multi-centre study of bemcentinib (BGB324), a first-in-class selective AXL inhibitor, in combination with pembrolizumab in patients with advanced NSCLC.
James Lorens et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
TLR4-Based Immunotherapeutics in Cancer: A Review of the Achievements and Shortcomings
Maryam A. Shetab Boushehri et al.
MOLECULAR PHARMACEUTICS (2018)
Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors
Pedro Miguel Lacal et al.
PHARMACOLOGICAL RESEARCH (2018)
Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling
Muhammad Waqas Usman et al.
CELL DEATH & DISEASE (2018)
LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment
Changhao Chen et al.
NATURE COMMUNICATIONS (2018)
Alveolar Macrophages in the Resolution of Inflammation, Tissue Repair, and Tolerance to Infection
Benoit Allard et al.
FRONTIERS IN IMMUNOLOGY (2018)
Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity
Marte Fauskanger et al.
FRONTIERS IN IMMUNOLOGY (2018)
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Marc O. Johnson et al.
CELL (2018)
Trends in the global immuno-oncology landscape
Jun Tang et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer
Marjorie De la Fuente López et al.
TUMOR BIOLOGY (2018)
Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1
Zhi-Fa Wen et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
M2C Polarization by Baicalin Enhances Efferocytosis via Upregulation of MERTK Receptor
Yin-Siew Lai et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2018)
The expression of PD-1 ligands and IDO1 by macrophage/microglia in primary central nervous system lymphoma
Yuko Miyasato et al.
JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY (2018)
Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
Kun-Yu Teng et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Single-cell barcoding and sequencing using droplet microfluidics
Rapolas Zilionis et al.
NATURE PROTOCOLS (2017)
GM-CSF- and M-CSF-primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures
Ana Lukic et al.
FASEB JOURNAL (2017)
The ectonucleotidases CD39 and CD73: Novel checkpoint inhibitor targets
Bertrand Allard et al.
IMMUNOLOGICAL REVIEWS (2017)
Anti-CD24 neutralizing antibody exacerbates Concanavalin A-induced acute liver injury in mice via liver M1 macrophages
Hongyu Liu et al.
IMMUNOLOGY LETTERS (2017)
Complement C3-dependent uptake of targeted liposomes into human macrophages, B cells, dendritic cells, neutrophils, and MDSCs
Alexandra Francian et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)
Hsp70 acetylation prevents caspase-dependent/independent apoptosis and autophagic cell death in cancer cells
Y. Hoi Park et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Is CD47 an innate immune checkpoint for tumor evasion?
Xiaojuan Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro
Hiromi Shiratori et al.
MOLECULAR IMMUNOLOGY (2017)
Immunosuppressive macrophages induced by IDO1 promote the growth of endometrial stromal cells in endometriosis
Jie Mei et al.
MOLECULAR MEDICINE REPORTS (2017)
Induction of immunogenic cell death of tumors by newly synthesized heterocyclic quinone derivative
Keum-joo Son et al.
PLOS ONE (2017)
Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications
Dana M. Hardbower et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
Woosung Chung et al.
NATURE COMMUNICATIONS (2017)
Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling
Chi-Fu Chiang et al.
ONCOTARGET (2017)
CD47 promotes ovarian cancer progression by inhibiting macrophage phagocytosis
Ran Liu et al.
ONCOTARGET (2017)
Tumor necrosis and infiltrating macrophages predict survival after curative resection for cholangiocarcinoma
Georgi Atanasov et al.
ONCOIMMUNOLOGY (2017)
Topical Imiquimod Plus Nab-paclitaxel for Breast Cancer Cutaneous Metastases A Phase 2 Clinical Trial
Lupe G. Salazar et al.
JAMA ONCOLOGY (2017)
Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment
Susanne M. Steggerda et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment
Soren Muller et al.
GENOME BIOLOGY (2017)
Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles
Marlies Cortes et al.
EMBO JOURNAL (2017)
Gefitinib inhibits M2-like polarization of tumor-associated macrophages in Lewis lung cancer by targeting the STAT6 signaling pathway
Muhammad Tariq et al.
ACTA PHARMACOLOGICA SINICA (2017)
Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
Vinit Kumar et al.
CANCER CELL (2017)
The immune response to secondary necrotic cells
Monika Sachet et al.
APOPTOSIS (2017)
First-in-Human Study of AMG 820, a Monoclonal Anti-Colony-Stimulating Factor 1 Receptor Antibody, in Patients with Advanced Solid Tumors
Kyriakos P. Papadopoulos et al.
CLINICAL CANCER RESEARCH (2017)
Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade
Dipongkor Saha et al.
CANCER CELL (2017)
Progress in tumor-associated macrophage (TAM)-targeted therapeutics
Chayanon Ngambenjawong et al.
ADVANCED DRUG DELIVERY REVIEWS (2017)
Purinergic signaling during macrophage differentiation results in M2 alternative activated macrophages
Maria Barbera-Cremades et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2016)
Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study
Nicholas Butowski et al.
NEURO-ONCOLOGY (2016)
CDH1 germline mutations and hereditary lobular breast cancer
Giovanni Corso et al.
FAMILIAL CANCER (2016)
Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice
Kouichi Miura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer
Kipp Weiskopf et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation
Neil M. Iyengar et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
Timothy M. Nywening et al.
LANCET ONCOLOGY (2016)
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery
Simon Heidegger et al.
NANOSCALE (2016)
PI3Kγ is a molecular switch that controls immune suppression
Megan M. Kaneda et al.
NATURE (2016)
Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
Saeid Zanganeh et al.
NATURE NANOTECHNOLOGY (2016)
Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells
S. Y. Lim et al.
ONCOGENE (2016)
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Patrik L. Stahl et al.
SCIENCE (2016)
Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR
Xiaofan Guo et al.
ONCOTARGET (2016)
Targeting CD73 in the tumor microenvironment with MEDI9447
Carl M. Hay et al.
ONCOIMMUNOLOGY (2016)
Anti-CD73 in Cancer Immunotherapy: Awakening New Opportunities
Luca Antonioli et al.
TRENDS IN CANCER (2016)
Macrophage subtype predicts lymph node metastasis in oesophageal adenocarcinoma and promotes cancer cell invasion in vitro
Wenqing Cao et al.
BRITISH JOURNAL OF CANCER (2015)
Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy
Russell Hughes et al.
CANCER RESEARCH (2015)
Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
Allon M. Klein et al.
CELL (2015)
Clinical and Biological Effects of an Agonist Anti-CD40 Antibody: A Cancer Research UK Phase I Study
Peter Johnson et al.
CLINICAL CANCER RESEARCH (2015)
An Open-Label, Multicenter, Phase I/II Study of JNJ-40346527, a CSF-1R Inhibitor, in Patients with Relapsed or Refractory Hodgkin Lymphoma
Bastian von Tresckow et al.
CLINICAL CANCER RESEARCH (2015)
Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection
Camille Bleriot et al.
IMMUNITY (2015)
TNF-alpha modulates adipose macrophage polarization to M1 phenotype in response to scorpion venom
Aouatef Ait-Lounis et al.
INFLAMMATION RESEARCH (2015)
A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer
Mythili Koneru et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Principles of nanoparticle design for overcoming biological barriers to drug delivery
Elvin Blanco et al.
NATURE BIOTECHNOLOGY (2015)
Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk
Mingye Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
David Hong et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells
C. Tran Quang et al.
CELL DEATH & DISEASE (2015)
Cancer Metastasis: Perivascular Macrophages Under Watch
Ece Kadioglu et al.
CANCER DISCOVERY (2015)
High PD-L1 expression was associated with poor prognosis in 870 Chinese patients with breast cancer
Tao Qin et al.
ONCOTARGET (2015)
CCL18 from tumor-associated macrophages promotes angiogenesis in breast cancer
Ling Lin et al.
ONCOTARGET (2015)
Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo
Orsolya Kiraly et al.
PLOS GENETICS (2015)
Tumors: Wounds That Do Not Heal-Redux
Harold F. Dvorak
CANCER IMMUNOLOGY RESEARCH (2015)
Novel Mechanism of Macrophage-Mediated Metastasis Revealed in a Zebrafish Model of Tumor Development
Jian Wang et al.
CANCER RESEARCH (2015)
Macrophage-secreted IL-8 induces-epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway
Xiu-Tao Fu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2015)
Polarisation of Tumor-Associated Macrophages toward M2 Phenotype Correlates with Poor Response to Chemoradiation and Reduced Survival in Patients with Locally Advanced Cervical Cancer
Marco Petrillo et al.
PLOS ONE (2015)
Human breast cancer cells educate macrophages toward the M2 activation status
Sofia Sousa et al.
BREAST CANCER RESEARCH (2015)
Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo
Nadine Jetten et al.
ANGIOGENESIS (2014)
Nuclear Factor of Activated T-cell Activity Is Associated with Metastatic Capacity in Colon Cancer
Manish K. Tripathi et al.
CANCER RESEARCH (2014)
Tumor-associated macrophages promote the metastatic potential of thyroid papillary cancer by releasing CXCL8
Weiyuan Fang et al.
CARCINOGENESIS (2014)
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
Yonit Lavin et al.
CELL (2014)
Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction
Timo Heidt et al.
CIRCULATION RESEARCH (2014)
Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses
Emine Sahin et al.
JOURNAL OF IMMUNOLOGY (2014)
A Macrophage-Dominant PI3K Isoform Controls Hypoxia-Induced HIF1α and HIF2α Stability and Tumor Growth, Angiogenesis, and Metastasis
Shweta Joshi et al.
MOLECULAR CANCER RESEARCH (2014)
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
Laura Bonapace et al.
NATURE (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities
Erin D. Lew et al.
ELIFE (2014)
A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy
Przemyslaw W. Twardowski et al.
ANTI-CANCER DRUGS (2013)
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes
Daigo Hashimoto et al.
IMMUNITY (2013)
Possible anti-tumor activity of initial treatment with zoledronic acid with hormonal therapy for bone-metastatic prostate cancer in multicenter clinical trial
Hiroji Uemura et al.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2013)
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis
Rebecca S. Cook et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
High efficacy of CpG-ODN, Cetuximab and Cisplatin combination for very advanced ovarian xenograft tumors
Michele Sommariva et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
Diane Tseng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
Alessandro Michelucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells
Stefani Spranger et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Macrophage M1/M2 Polarization Dynamically Adapts to Changes in Cytokine Microenvironments in Cryptococcus neoformans Infection
Michael J. Davis et al.
MBIO (2013)
The TSC-mTOR pathway regulates macrophage polarization
Vanessa Byles et al.
NATURE COMMUNICATIONS (2013)
Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro
Simon Heuking et al.
JOURNAL OF NANOBIOTECHNOLOGY (2013)
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
Jagdeep K. Singh et al.
BREAST CANCER RESEARCH (2013)
Randomized clinical trial of imiquimod: an adjunct to treating cervical dysplasia
Deirdre R. Pachman et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2012)
Small interfering RNA targeting HMGN5 induces apoptosis via modulation of a mitochondrial pathway and Bcl-2 family proteins in prostate cancer cells
Xiao-Yu Zhang et al.
ASIAN JOURNAL OF ANDROLOGY (2012)
Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
Anne-Katrine Bonde et al.
BMC CANCER (2012)
TNF-α Mediates Macrophage-Induced Bystander Effects through Netrin-1
Yonghong Yang et al.
CANCER RESEARCH (2012)
Impact of the small molecule Met inhibitor BMS-777607 on the metastatic process in a rodent tumor model with constitutive c-Met activation
Yao Dai et al.
CLINICAL & EXPERIMENTAL METASTASIS (2012)
Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer
Sylvia Adams et al.
CLINICAL CANCER RESEARCH (2012)
Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity
Yewei Ji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Phase I study of the anti-CD40 humanized monoclonal antibody lucatumumab (HCD122) in relapsed chronic lymphocytic leukemia
John C. Byrd et al.
LEUKEMIA & LYMPHOMA (2012)
Differential Macrophage Activation Alters the Expression Profile of NTPDase and Ecto-5′-Nucleotidase
Rafael Fernandes Zanin et al.
PLOS ONE (2012)
A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis
Houda Z. Elloumi et al.
PLOS ONE (2012)
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
Alicia Arranz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR A novel IDO effector pathway targeted by D-1-methyl-tryptophan
Richard Metz et al.
ONCOIMMUNOLOGY (2012)
Expression patterns of the immunomodulatory enzyme arginase 1 in blood, lymph nodes and tumor tissue of early-stage breast cancer patients
Jana de Boniface et al.
ONCOIMMUNOLOGY (2012)
Immunogenic cell death and DAMPs in cancer therapy
Dmitri V. Krysko et al.
NATURE REVIEWS CANCER (2012)
Dasatinib as a Single Agent in Triple-Negative Breast Cancer: Results of an Open-Label Phase 2 Study
Richard S. Finn et al.
CLINICAL CANCER RESEARCH (2011)
Inflammation and wound healing: the role of the macrophage
Timothy J. Koh et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2011)
COMPLETE RESTORATION OF REFRACTORY MANDIBULAR OSTEORADIONECROSIS BY PROLONGED TREATMENT WITH A PENTOXIFYLLINE-TOCOPHEROL-CLODRONATE COMBINATION (PENTOCLO): A PHASE II TRIAL
Sylvie Delanian et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
Bin-Zhi Qian et al.
NATURE (2011)
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction
Guo-Yun Chen et al.
NATURE BIOTECHNOLOGY (2011)
Nilotinib: A Novel, Selective Tyrosine Kinase Inhibitor
Jean-Yves Blay et al.
SEMINARS IN ONCOLOGY (2011)
The redox protein HMGB1 regulates cell death and survival in cancer treatment
Daolin Tang et al.
AUTOPHAGY (2010)
Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation
Melissa Sandahl et al.
BMC DEVELOPMENTAL BIOLOGY (2010)
R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Sacha J. Holland et al.
CANCER RESEARCH (2010)
Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages
Qingshan Wang et al.
CELL RESEARCH (2010)
Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis
Nora B. Caberoy et al.
EMBO JOURNAL (2010)
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
Takashi Satoh et al.
NATURE IMMUNOLOGY (2010)
Introduction to metallic nanoparticles
Vicky V. Mody et al.
JOURNAL OF PHARMACY AND BIOALLIED SCIENCES (2010)
Lung environment determines unique phenotype of alveolar macrophages
Amanda M. Guth et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Chemotherapy induces ATP release from tumor cells
Isabelle Martins et al.
CELL CYCLE (2009)
CD24 and Siglec-10 Selectively Repress Tissue Damage-Induced Immune Responses
Guo-Yun Chen et al.
SCIENCE (2009)
An exploratory study of systemic administration of the Toll-like receptor-7 agonist 852A in patients with refractory metastatic melanoma
Reinhard Dummer et al.
CLINICAL CANCER RESEARCH (2008)
Inhibition of self engulfment through deactivation of myosin-II at the phagocytic synapse between human cells
Richard K. Tsai et al.
JOURNAL OF CELL BIOLOGY (2008)
Colony-stimulating factors in inflammation and autoimmunity
John A. Hamilton
NATURE REVIEWS IMMUNOLOGY (2008)
TAM receptors are pleiotropic inhibitors of the innate immune response
Carla V. Rothlin et al.
CELL (2007)
First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agionist, to activate innate immune responses in patients with advanced cancer
Arkadiusz Z. Dudek et al.
CLINICAL CANCER RESEARCH (2007)
High mobility group box I (HMGB1) release from tumor cells after treatment: Implications for development of targeted chemoimmunotherapy
Xiang Da (Eric) Dong et al.
JOURNAL OF IMMUNOTHERAPY (2007)
Phase 1, pharmacokinetic (PK) and pharmacodynamic (PD) study of oral alvespimycin (A; KOS-1022; 17-DMAG): Two different schedules in patients with advanced malignancies
K. T. Flaherty et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Meta-analysis of clodronate and breast cancer survival
T. C. Ha et al.
BRITISH JOURNAL OF CANCER (2007)
Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody
Robert H. Vonderheide et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses
De-Yan Hou et al.
CANCER RESEARCH (2007)
The extracellular release of HMGB1 during apoptotic cell death
Charles W. Bell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
Fernando O. Martinez et al.
JOURNAL OF IMMUNOLOGY (2006)
Clodronate-liposome-mediated depletion of tumour-associated macrophages:: a new and highly effective antiangiogenic therapy approach
S. M. Zeisberger et al.
BRITISH JOURNAL OF CANCER (2006)
Efficacy and safety of zoledronic acid in patients with breast cancer metastatic to bone: A multicenter clinical trial
Giacomo Carteni et al.
ONCOLOGIST (2006)
Development of real-time subcellular dynamic multicolor imaging of cancer-cell trafficking in live mice with a variable-magnification whole-mouse imaging system
K Yamauchi et al.
CANCER RESEARCH (2006)
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ- and CD40L-mediated costimulation
Frank A. W. Verreck et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2006)
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
SJ Gardai et al.
CELL (2005)
Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells
SI Abdalla et al.
CARCINOGENESIS (2005)
Evodiamine abolishes constitutive and inducible NF-κB activation by inhibiting IκBα kinase activation, thereby suppressing NF-κB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion
Y Takada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2, macrophages subvert, immunity to (myco)bacteria
FAW Verreck et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A
PP Manna et al.
CANCER RESEARCH (2004)
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
PC Rodriguez et al.
CANCER RESEARCH (2004)
CpG oligodeoxynucleotide enhances tumor response to radiation
L Milas et al.
CANCER RESEARCH (2004)
The chemokine system in diverse forms of macrophage activation and polarization
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2004)
A novel mechanism for TNF-α regulation by p38 MAPK:: Involvement of NF-κB with implications for therapy in rheumatoid arthritis
J Campbell et al.
JOURNAL OF IMMUNOLOGY (2004)
Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
J Vollmer et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
The three Es of cancer immunoediting
GP Dunn et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Induction of heat shock proteins (HSPs) by sodium arsenite in cultured astrocytes and reduction of hydrogen peroxide-induced cell death
B Fauconneau et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis
SF Schoppmann et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Mer receptor tyrosine kinase signaling.: Prevention of apoptosis and alteration of cytoskeletal architecture without stimulation or proliferation.
KL Guttridge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
p38 mitogen-activated protein kinase is activated and linked to TNF-α signaling in inflammatory bowel disease
GH Waetzig et al.
JOURNAL OF IMMUNOLOGY (2002)
Human macrophage activation programs induced by bacterial pathogens
GJ Nau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Positive regulatory role of IL-12 in macrophages and modulation by IFN-γ
U Grohmann et al.
JOURNAL OF IMMUNOLOGY (2001)
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
V Shankaran et al.
NATURE (2001)
Distinct modes of macrophage recognition for apoptotic and necrotic cells are not specified exclusively by phosphatidylserine exposure
RE Cocco et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
M-1/M-2 macrophages and the Th1/Th2 paradigm
CD Mills et al.
JOURNAL OF IMMUNOLOGY (2000)