☆ 4.6 Review

Photodynamic Therapy-An Up-to-Date Review

APPLIED SCIENCES-BASEL (2021)

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Review Biochemistry & Molecular Biology

Photodynamic cancer therapy: role of Ag- and Au-based hybrid nano-photosensitizers

K. I. Dhanalekshmi et al.

Summary: Photodynamic therapy (PDT) is being increasingly utilized as an effective treatment modality for cancer. However, the organic photosensitizers employed for PDT have some limitations. Therefore, there is growing interest in the use of non-toxic inorganic photosensitizers such as noble metal nanoparticles.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)

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Review Oncology

Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol

Nkune W. Nkune et al.

Summary: Colorectal Cancer (CRC) is a highly lethal disease with limited treatment options and a tendency for resistance and metastasis. Photodynamic Therapy (PDT) and Cannabidiol (CBD) have shown promise in enhancing CRC treatment outcomes by reducing resistance and spreading, while minimizing side effects.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2021)

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Review Oncology

A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment

Ahmed El-Hussein et al.

Summary: Cancer, with lung cancer as a leading cause of cancer-related death, often develops drug resistance to chemotherapy. Photodynamic Therapy (PDT) has emerged as an effective treatment modality against various malignant neoplasms and tumors. The combination of PDT and chemotherapy can promote synergistic effects and enhance cancer eradication efficacy.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2021)

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Review Oncology

Photodynamic diagnosis and therapy for urothelial carcinoma and prostate cancer: new imaging technology and therapy

Hideo Fukuhara et al.

Summary: Photodynamic technology utilizes light-sensitive and fluorescent substances to accurately diagnose various malignancies by accumulating specifically in tumor cells. This technology enables precise diagnosis and complete resection during surgery, making it a potential treatment option for cancer.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2021)

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Review Gastroenterology & Hepatology

Photodynamic Therapy for Esophageal Cancer

Takahiro Inoue et al.

Summary: Photodynamic therapy is a curative treatment for esophageal squamous cell carcinoma, particularly for cases where surgery or endoscopic resection may be difficult. By activating a photosensitizer with laser light, photodynamic therapy can effectively target and treat local tumor recurrences.

CLINICAL ENDOSCOPY (2021)

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Article Materials Science, Multidisciplinary

A covalent organic framework-based multifunctional therapeutic platform for enhanced photodynamic therapy via catalytic cascade reactions

Lihan Cai et al.

Summary: Utilizing COFs as a template, Au nanoparticles grown on the surface, coated with MnO2, and introducing HA, the COF-Au-MnO2 product can perform cascade reactions in the tumor microenvironment, demonstrating excellent cancer cell killing effects and antitumor efficacy via a cycle-like process.

SCIENCE CHINA-MATERIALS (2021)

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Article Chemistry, Applied

New poly(acrylamide) nanoparticles in the development of third generation photosensitizers

M. S. Gualdesi et al.

Summary: The study focused on developing third generation photosensitizers using PAA-NPs for antimicrobial photodynamic therapy. These new photosensitizers exhibited improved photochemical reactivity and photodynamic efficacy, showing potential applications against Gram-positive and Gram-negative bacteria.

DYES AND PIGMENTS (2021)

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Review Pharmacology & Pharmacy

Current applications of drug delivery nanosystems associated with antimicrobial photodynamic therapy for oral infections

Amanda Leticia Polli Silvestre et al.

Summary: The oral cavity is colonized by various microorganisms that can lead to dental diseases, and conventional treatment may result in side effects and resistance. Developing alternative therapies like Antimicrobial Photodynamic Therapy (aPDT) combined with nanotechnology can optimize treatment outcomes and provide better therapeutic effects.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Article Biochemistry & Molecular Biology

Hot-melt extrusion of photodynamic antimicrobial polymers for prevention of microbial contamination

Matthew P. Wylie et al.

Summary: Infectious disease outbreaks within healthcare facilities can worsen patient illness, and antimicrobial surfaces have become crucial in healthcare infection control. This study utilized hot-melt extrusion to manufacture antimicrobial polymer surfaces containing the photosensitizer TBO, demonstrating significant antibacterial activity.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2021)

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Review Oncology

Features of third generation photosensitizers used in anticancer photodynamic therapy: Review

Ivan S. Mfouo-Tynga et al.

Summary: Cancer is a major global health issue and photodynamic therapy using photosensitizers is an approved therapeutic option. The success of this therapy depends on the quality and improvement of photosensitizer drugs, with bioconjugation and encapsulation with targeting moieties playing a key role in developing more efficient photosensitizers for cancer treatment. Despite significant advances, the development of next-generation photosensitizers is still mainly in the developmental stage.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

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Review Chemistry, Analytical

Optical Technologies for the Improvement of Skin Cancer Diagnosis: A Review

Laura Rey-Barroso et al.

Summary: The global incidence of skin cancer, especially melanoma, is rapidly increasing, posing a significant burden on health and economy. Research is focused on early detection and better understanding of the disease to improve survival rates.

SENSORS (2021)

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Review Chemistry, Physical

Biomedical Applications of Reactive Oxygen Species Generation by Metal Nanoparticles

Roberto Canaparo et al.

Summary: The design, synthesis and characterization of new nanomaterials in biomedical field is a dynamic and transversal aspect of nanotechnology applications. Metal-based nanoparticles (MNPs) are widely used in biomedicine due to their physical and chemical properties. Researchers and clinicians are setting and standardizing treatments by tuning ROS production to induce cancer or microbial cell death.

MATERIALS (2021)

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Review Nanoscience & Nanotechnology

Photosensitizer Nanoparticles Boost Photodynamic Therapy for Pancreatic Cancer Treatment

Huanyu Yang et al.

Summary: Current clinical studies review the use of photodynamic therapy with nanoparticles in treating pancreatic cancer. Nanoparticles have advantages in improving the efficacy of photodynamic therapy for pancreatic cancer treatment. Challenges and future outlook in developing nanoparticle-based photodynamic therapy for pancreatic cancer are discussed.

NANO-MICRO LETTERS (2021)

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Article Chemistry, Medicinal

Morphological Changes and Prognostic Factors before and after Photodynamic Therapy for Central Serous Chorioretinopathy

Yu Wakatsuki et al.

Summary: This study investigated the effects of verteporfin hPDT on CSC by analyzing changes in visual acuity, central retinal thickness, central choroidal thickness, and IR images before and after treatment. The results showed significant improvements in CCT, CRT, visual acuity, and IR image luminance at one and three months post-treatment, indicating the efficacy of hPDT for CSC and the improvement of IR images over time.

PHARMACEUTICALS (2021)

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Article Nanoscience & Nanotechnology

Copper Sulfide Nanoassemblies for Catalytic and Photoresponsive Eradication of Bacteria from Infected Wounds

Amit Nain et al.

Summary: BSA-encapsulated copper sulfide nanocrystals (CuS NCs) were prepared and exhibited enzyme-like and photodynamic activities. under NIR laser irradiation, the antimicrobial response was significantly enhanced and >99% of bacteria were eradicated in just 1 min. The BSA-CuS NCs showed insignificant cytotoxicity and hemolysis, making them highly biocompatible bactericides for effective bacteria eradication in preclinical applications.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Article Dentistry, Oral Surgery & Medicine

Efficacy of antimicrobial photodynamic therapy with Rose Bengal and blue light against cariogenic bacteria

Marina Hirose et al.

Summary: The study demonstrated that antimicrobial photodynamic therapy (a-PDT) using Rose Bengal and blue light LED effectively targeted cariogenic bacteria, reducing their presence in both planktonic and biofilm conditions, as well as in saliva and dental plaques. This approach shows promise for controlling dental caries in dental surgery.

ARCHIVES OF ORAL BIOLOGY (2021)

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Article Biochemistry & Molecular Biology

Combination of talaporfin photodynamic therapy and Poly (ADP-Ribose) polymerase (PARP) inhibitor in gastric cancer

Mamoru Tanaka et al.

Summary: The study investigated the efficacy of combining talaporfin PDT with olaparib for gastric cancer treatment, demonstrating excellent synergistic action and significant tumor growth suppression. This combination therapy has the potential to be an effective antitumor treatment for gastric cancer.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)

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Review Dentistry, Oral Surgery & Medicine

Indocyanine green-mediated antimicrobial photodynamic therapy as an adjunct to periodontal therapy: a systematic review and meta-analysis

Nasir Zeeshan Bashir et al.

Summary: The use of adjunctive ICG-PDT in non-surgical periodontal therapy leads to significant improvements in probing pocket depth and clinical attachment level at 3 and 6 months post-therapy for chronic periodontitis patients. No adverse events were reported. Additional research is needed to explore variables such as different photosensitiser concentrations and parameters associated with the light source.

CLINICAL ORAL INVESTIGATIONS (2021)

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Article Nutrition & Dietetics

A longitudinal association between the traditional Japanese diet score and incidence and mortality of breast cancer-an ecological study

Chisato Abe et al.

Summary: The study investigates the longitudinal association between the traditional Japanese diet score and breast cancer incidence and mortality. Countries with higher traditional Japanese diet scores tended to have lower distributions of breast cancer incidence and mortality.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2021)

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Article Biochemistry & Molecular Biology

Chitosan-riboflavin composite film based on photodynamic inactivation technology for antibacterial food packaging

Linyue Su et al.

Summary: The study successfully applied Photodynamic Inactivation (PDI) technology to food packaging using chitosan films containing riboflavin, resulting in composite films with improved properties. The addition of riboflavin not only enhanced the film characteristics, but also generated sufficient singlet oxygen to inactivate food-borne pathogens and spoilage bacteria.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

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Article Biochemistry & Molecular Biology

Biotin-Containing Third Generation Glucoheptoamidated Polyamidoamine Dendrimer for 5-Aminolevulinic Acid Delivery System

Aleksandra Kaczorowska et al.

Summary: In this study, Polyamidoamine PAMAM dendrimer generation 3 (G3) was modified with biotin and glucoheptoamidated to obtain a series of conjugates with different numbers of biotin residues, which were used as host molecules to encapsulate 5-aminolevulinic acid. The interaction between host and guest molecules was characterized by NMR, revealing an increase in solubility of 5-aminolevulinic acid in water. Moreover, the encapsulates showed potential for delivering 5-aminolevulinic acid to cells without cytotoxic effects, and aqueous encapsulates were found to be more effective in this regard.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Biochemistry & Molecular Biology

Functional titanium dioxide nanoparticle conjugated with phthalocyanine and folic acid as a promising photosensitizer for targeted photodynamic therapy in vitro and in vivo

Xinyue Liang et al.

Summary: The study presents a novel photosensitizer FA-TiO2-Pc with high targeted photodynamic therapeutic activity and excellent biocompatibility, showing great potential for treatment of folate receptor positive cancer cells.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2021)

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Article Biochemistry & Molecular Biology

Photophysical and Bactericidal Properties of Pyridinium and Imidazolium Porphyrins for Photodynamic Antimicrobial Chemotherapy

Florent Le Guern et al.

Summary: The study reports the synthesis and characterization of tetracationic porphyrins from three families, comparing their photophysical properties with a well-known pyridinium porphyrin family. The results show that these new photosensitizers may offer a good alternative, especially against S. aureus and E. coli, and pave the way for new cationic photosensitizers through derivatization.

MOLECULES (2021)

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Article Oncology

Antiviral photodynamic therapy: Inactivation and inhibition of SARS-CoV-2 in vitro using methylene blue and Radachlorin

Victor A. Svyatchenko et al.

Summary: PDT combined with MB and Radachlorin demonstrated high antiviral activity against SARS-CoV-2 in vitro, inactivating viral suspensions with TCID50 greater than 103 and protecting Vero E6 cells from infection.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

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Review Oncology

Photodynamic therapy for prostate cancer - A narrative review

Michal Osuchowski et al.

Summary: This article reviews the treatment approaches for low and high-grade prostate cancer, discussing the importance of active treatment vs. active surveillance for low-grade prostate cancer patients. It highlights photodynamic therapy as an option for active treatment of low-grade prostate cancer, examining the mechanisms, clinical methods, and key points from recent clinical trials. Additionally, it explores experimental methodologies for photodynamic prostate cancer treatment, photodynamic diagnosis, fluorescence guided resection, and PSMA-targeted PDT.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

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Article Chemistry, Analytical

In Vivo Quantitative Vasculature Segmentation and Assessment for Photodynamic Therapy Process Monitoring Using Photoacoustic Microscopy

Thi Thao Mai et al.

Summary: The study investigated the effect of photodynamic therapy on vascular changes in mouse ear melanoma tumors using label-free quantitative photoacoustic microscopy. The results demonstrated the potential of this quantitative approach to evaluate the effectiveness of the PDT method.

SENSORS (2021)

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Article Chemistry, Multidisciplinary

Interactions of a Water-Soluble Glycofullerene with Glucose Transporter 1. Analysis of the Cellular Effects on a Pancreatic Tumor Model

Edyta Baranska et al.

Summary: Carbon nanomaterials, especially fullerene derivatives, have been extensively studied for their potential applications in biomedical research, particularly as drug delivery vehicles. This study focuses on the use of a highly water-soluble glycofullerene in pancreatic cancer research, showing its promising potential as a drug delivery vehicle for treating pancreatic cancer. The results did not demonstrate any influence of the glycofullerene on cancer cellular events and glycolysis, indicating its potential efficacy in pancreatic cancer treatment.

NANOMATERIALS (2021)

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Review Chemistry, Multidisciplinary

Yttrium Oxide Nanoparticle Synthesis: An Overview of Methods of Preparation and Biomedical Applications

Govindasamy Rajakumar et al.

Summary: Yttrium oxide nanoparticles are highly sought after in technical applications due to their favorable properties such as high dielectric constant and thermal stability. They are utilized in a variety of fields, including biological imaging and photodynamic therapies, and exhibit attractive antibacterial and antioxidant properties. However, there are also some drawbacks associated with their use.

APPLIED SCIENCES-BASEL (2021)

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Review Materials Science, Multidisciplinary

Mechanism and factors influence of graphene-based nanomaterials antimicrobial activities and application in dentistry

Asanah Radhi et al.

Summary: Graphene-based nanomaterials (GBNs) have excellent antimicrobial properties by disrupting bacterial cell membrane integrity and generating reactive oxygen species (ROS). The antimicrobial effects of GBNs are influenced by factors such as microbial cell morphology, GBNs characteristics, and concentration. Potential clinical applications of GBNs in dentistry include denture fabrication, restorative treatment, orthodontic treatment, and dental implant treatment.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2021)

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Review Materials Science, Multidisciplinary

Novel Approaches to Combat Medical Device-Associated BioFilms

Xin Li et al.

Summary: Biofilms are formed by microorganisms as a protective survival state to resist antimicrobial agents and host immune responses. They pose a serious threat to human health, especially in medical device-associated infections, and traditional antimicrobial agents are ineffective. New treatment strategies are urgently needed to address biofilm infections.

COATINGS (2021)

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Review Medicine, General & Internal

Potential of Photodynamic Therapy Based on Sugar-Conjugated Photosensitizers

Hiromi Kataoka et al.

Summary: The third-generation PDT based on the Warburg effect, utilizing sugar-conjugated chlorins, shows stronger antitumor effects and induces immunogenic cell death, potentially synergizing with immune checkpoint blockers for enhanced anticancer effects.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Oncology

Survival Outcomes with Photodynamic Therapy, Chemotherapy and Radiation in Patients with Stage III or Stage IV Non-Small Cell Lung Cancer

Sumedha Chhatre et al.

Summary: The addition of photodynamic therapy (PDT) to chemotherapy and radiation therapy offers better survival benefit than radiation therapy alone in non-small cell lung cancer (NSCLC) patients who are not eligible for surgery. Studies show a lower risk of mortality for patients receiving PDT in combination with radiation and chemotherapy compared to those receiving radiation alone.

CANCERS (2021)

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Review Pharmacology & Pharmacy

Inorganic Nanoparticles Applied for Active Targeted Photodynamic Therapy of Breast Cancer

Hanieh Montaseri et al.

Summary: Photodynamic therapy (PDT) is an alternative cancer treatment method that utilizes specific light wavelengths to target and eliminate cancer cells, with nanoparticles showing significant advantages in solubility, biodistribution, and cellular penetration compared to free photosensitizers. This review focuses on the use of inorganic nanoparticles in PDT for breast cancer treatment over the past decade, highlighting their effectiveness in active targeting strategies.

PHARMACEUTICS (2021)

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Article Microbiology

Visible Lights Combined with Photosensitizing Compounds Are Effective against Candida albicans Biofilms

Priyanka Bapat et al.

Summary: Research suggests that blue light alone can inhibit and disrupt Candida albicans biofilms, while red and green lights only inhibit biofilm formation when combined with photosensitizing compounds. These findings indicate that photodynamic therapy could be an effective non-drug treatment for fungal biofilm infections that deserves further exploration.

MICROORGANISMS (2021)

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Article Microbiology

Photodynamic Eradication of Trichophyton rubrum and Candida albicans

Anton Valkov et al.

Summary: Conventional methods of onychomycosis treatment may be ineffective, leading to the crucial need for research and development of new treatment methods. By testing different photosensitizers and formulation components, an effective formulation for photodynamic therapy (PDT) treatment of onychomycosis was found, showing potential for future optimization and acceleration.

PATHOGENS (2021)

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Article Health Care Sciences & Services

Tumor Environment-Responsive Hyaluronan Conjugated Zinc Protoporphyrin for Targeted Anticancer Photodynamic Therapy

Shanghui Gao et al.

Summary: A tumor environment-responsive nanoprobe, HA-es-ZnPP, was synthesized for targeted tumor accumulation and effective internalization, showing significant anticancer PDT effect both in vitro and in vivo.

JOURNAL OF PERSONALIZED MEDICINE (2021)

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Article Biology

Correlation of the ALA-PDT Treatment Efficacy and the HPV Genotype Profile of Genital Warts after Cryotherapy Failure and Podophyllotoxin Therapy in Male Patients

Witold Owczarek et al.

Summary: The study showed that photodynamic therapy is effective in treating persistent genital warts in male patients, leading to clearance of DNA HPV. Treatment efficacy varied based on the HPV types present in the patients, with slightly lower eradication rates for high-risk HPV types compared to low-risk HPV types.

LIFE-BASEL (2021)

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Review Oncology

A systematic review of photodynamic therapy as an antiviral treatment: Potential guidance for dealing with SARS-CoV-2

Pollyanna C. V. Conrado et al.

Summary: The research evaluated the effectiveness of photodynamic therapy in inactivating SARS-CoV-2. Most of the studies focused on in vitro experiments, with a few involving in vivo experiments. The results showed that photodynamic therapy has the potential to inactivate SARS-CoV-2.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2021)

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Review Chemistry, Applied

Photodynamic Therapy (PDT): An Alternative Approach for Combating COVID-19

Sunil Bhapkar et al.

Summary: The COVID-19 pandemic, originating in Wuhan, China, has prompted ongoing efforts to find effective treatments and vaccines, with limited success. Photodynamic therapy (PDT), commonly used in cancer treatment, is being explored as a potential alternative therapeutic approach for COVID-19, targeting SARS-CoV-2 proteins and RNA.

BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY (2021)

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Review Chemistry, Applied

Polymeric Nanoparticles for Breast Cancer Therapy: A Comprehensive Review

Ikmeet Kaur Grewal et al.

Summary: This article summarizes the advantages of using polymeric nanoparticles in the treatment of breast cancer, as well as provides a brief overview of research progress, patents, and clinical trials in this field reported in current literature.

BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY (2021)

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Article Chemistry, Applied

Comparative Assessment of Trace Elements in the Blood of Gastric Cancer Patients and Healthy Subjects

Annum Afzal et al.

Summary: The study compared the levels of trace elements in the blood of GC patients and healthy donors, finding significantly lower concentrations of zinc, iron, lead, cadmium, and chromium in the blood of GC patients. Significant variations in elemental concentrations were observed with factors such as gender, food habits, habitat, and smoking habits. Multivariate analysis showed significantly divergent distribution of elemental levels between GC patients and healthy subjects, possibly linked to altered metabolism of elements in GC patients.

BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY (2021)

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Letter Engineering, Biomedical

Recalcitrant viral warts treated with photodynamic therapy methyl aminolevulinate and red light (630 nm): a case series of 51 patients

Javier Alcantara-Gonzalez et al.

LASERS IN MEDICAL SCIENCE (2020)

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Review Dermatology

Antimicrobial photodynamic therapy in skin wound healing: A systematic review of animal studies

Yan Sun et al.

INTERNATIONAL WOUND JOURNAL (2020)

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Article Engineering, Biomedical

The influence of photodynamic therapy on the Warburg effect in esophageal cancer cells

Junqing Gan et al.

LASERS IN MEDICAL SCIENCE (2020)

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Review Biochemistry & Molecular Biology

Light Sources and Dosimetry Techniques for Photodynamic Therapy

Michele M. Kim et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2020)

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Review Biochemistry & Molecular Biology

Photodynamic Therapy for Gastrointestinal Cancer

Tomonori Yano et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2020)

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Article Oncology

Evaluation of the efficacy of 5-aminolevulinic acid photodynamic therapy for the treatment of vulvar lichen sclerosus

Zhijia Li et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Article Oncology

Porfimer sodium-mediated photodynamic therapy in patients with head and neck squamous cell carcinoma

Seiji Hosokawa et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Review Oncology

Photodynamic therapy with methyl-5-aminolevulinate for basal cell carcinoma: A systematic review and meta-analysis

Bi-Cheng Wang et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Article Medicine, General & Internal

An Efficient Photodynamic Therapy Treatment for Human Pancreatic Adenocarcinoma

Alexandre Quilbe et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Article Medicine, General & Internal

Photodynamic Therapy in Primary Breast Cancer

Shramana M. Banerjee et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Review Engineering, Biomedical

Advances in nanomaterials for photodynamic therapy applications: Status and challenges

Jianming Chen et al.

BIOMATERIALS (2020)

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Article Engineering, Environmental

Melanin -instructed biomimetic synthesis of copper sulfide for cancer phototheranostics

Chao Qi et al.

CHEMICAL ENGINEERING JOURNAL (2020)

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Article Chemistry, Applied

Inactivation of microbes on fruit surfaces using photodynamic therapy and its influence on the postharvest shelf-life of fruits

Xu Zhang et al.

FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL (2020)

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Review Chemistry, Multidisciplinary

Titanium Dioxide Nanoparticles: Prospects and Applications in Medicine

Daniel Ziental et al.

NANOMATERIALS (2020)

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Article Chemistry, Physical

Red and Near-Infrared Absorbing Dicyanomethylene Squaraine Cyanine Dyes: Photophysicochemical Properties and Anti-Tumor Photosensitizing Effects

Tiago D. Martins et al.

MATERIALS (2020)

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Article Chemistry, Multidisciplinary

Nanoscale Metal-Organic Frameworks Stabilize Bacteriochlorins for Type I and Type II Photodynamic Therapy

Taokun Luo et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

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Article Medicine, Research & Experimental

Radiolabeling, In Vitro Cell Uptake, and In Vivo Photodynamic Therapy Potential of Targeted Mesoporous Silica Nanoparticles Containing Zinc Phthalocyanine

Ozge Er et al.

MOLECULAR PHARMACEUTICS (2020)

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Review Pharmacology & Pharmacy

Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers

Jun Fang et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Review Biochemistry & Molecular Biology

Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?

Sherri A. McFarland et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2020)

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Article Engineering, Biomedical

Near infrared light-triggered metal ion and photodynamic therapy based on AgNPs/porphyrinic MOFs for tumors and pathogens elimination

Lu Zhang et al.

BIOMATERIALS (2020)

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Article Biochemistry & Molecular Biology

Effective Photodynamic Therapy for Colon Cancer Cells Using Chlorin e6 Coated Hyaluronic Acid-Based Carbon Nanotubes

Prabhavathi Sundaram et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Mycology

Treatment and management strategies of onychomycosis

R. Aggarwal et al.

JOURNAL DE MYCOLOGIE MEDICALE (2020)

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Article Pharmacology & Pharmacy

Biogenic Silver Nanoparticles Decorated with Methylene Blue Potentiated the Photodynamic Inactivation ofPseudomonas aeruginosaandStaphylococcus aureus

Paramanantham Parasuraman et al.

PHARMACEUTICS (2020)

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Article Infectious Diseases

Antimicrobial Photodynamic Therapy in the Control of COVID-19

Adelaide Almeida et al.

ANTIBIOTICS-BASEL (2020)

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Article Chemistry, Physical

Thionine in the design of new photosensitizers: Bromination and vehiculization in polymeric nanoparticles

M. S. Gualdesi et al.

JOURNAL OF MOLECULAR LIQUIDS (2020)

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Article Biochemistry & Molecular Biology

Chemical features of the photosensitizers new methylene blue N and S137 influence their subcellular localization and photoinactivation efficiency in Candida albicans

Gabriela Braga Rodrigues et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

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Article Oncology

Photodynamic therapy on prostate cancer cells involve mitochondria membrane proteins

Dan Dan Xu et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Review Oncology

Photodynamic therapy in wound healing in vivo: a systematic review

Jully Oyama et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Letter Optics

Photodynamic therapy for COVID-19

Nicholas Kipshidze et al.

NATURE PHOTONICS (2020)

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Letter Oncology

COVID-19: Beyond the virus. The use of photodynamic therapy for the treatment of infections in the respiratory tract

Lucas D. Dias et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Review Oncology

Photodynamic therapy of pancreatic cancer: Where have we come from and where are we going?

Yizhi Wang et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Article Materials Science, Biomaterials

Developing [60]Fullerene Nanomaterials for Better Photodynamic Treatment of Non-Melanoma Skin Cancers

Maciej Serda et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

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Article Oncology

Vascular Shutdown by Photodynamic Therapy Using Talaporfin Sodium

Taketo Suzuki et al.

CANCERS (2020)

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Article Oncology

Clinical treatment of intra-epithelia cervical neoplasia with photodynamic therapy

Antonio Carlos Figueiredo Vendette et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2020)

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Review Biochemistry & Molecular Biology

Perspectives of photodynamic therapy in biotechnology

Gabriela Klein Couto et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

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Article Biochemistry & Molecular Biology

Stacking Effects on Anthraquinone/DNA Charge-Transfer Electronically Excited States

Gustavo Cardenas et al.

MOLECULES (2020)

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Article Oncology

Antimicrobial photodynamic efficacy of selected natural photosensitizers against food pathogens: Impacts and interrelationship of process parameters

Truong Dang Le et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

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Article Chemistry, Multidisciplinary

Smart Dual-Functionalized Gold Nanoclusters for Spatio-Temporally Controlled Delivery of Combined Chemo- and Photodynamic Therapy

Andrea Tabero et al.

NANOMATERIALS (2020)

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Article Medicine, General & Internal

Improvement of Low Luminance Visual Acuity in Patients with Chronic Central Serous Chorioretinopathy after Half-Dose Verteporfin Photodynamic Therapy

Kyoko Fujita et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Review Biochemistry & Molecular Biology

Photo-Based Nanomedicines Using Polymeric Systems in the Field of Cancer Imaging and Therapy

Patihul Husni et al.

BIOMEDICINES (2020)

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Review Chemistry, Medicinal

Photodynamic Therapy with Verteporfin for Chronic Central Serous Chorioretinopathy: A Review of Data and Efficacy

Pierluigi Iacono et al.

PHARMACEUTICALS (2020)

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Review Chemistry, Multidisciplinary

Photodynamic diagnosis and photodynamic therapy of colorectal cancer in vitro and in vivo

Nokuphila Winifred Nompumelelo Simelane et al.

RSC ADVANCES (2020)

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Article Cell Biology

Photodynamic therapy induces autophagy-mediated cell death in human colorectal cancer cells via activation of the ROS/JNK signaling pathway

Changfeng Song et al.

CELL DEATH & DISEASE (2020)

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Review Gastroenterology & Hepatology

Ablative therapies for hepatic and biliary tumors: endohepatology coming of age

Jinendra Satiya et al.

TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Article Materials Science, Biomaterials

Amphiphilic phthalocyanines in polymeric micelles: a supramolecular approach toward efficient third-generation photosensitizers

Francesca Setaro et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Oncology

Verteporfin-photodynamic therapy is effective on gastric cancer cells

Yukari Mae et al.

MOLECULAR AND CLINICAL ONCOLOGY (2020)

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Review Medicine, Research & Experimental

Ultrasmall gold nanoparticles in cancer diagnosis and therapy

Miao Fan et al.

THERANOSTICS (2020)

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Review Oncology

Application of photodynamic therapy for liver malignancies

Heng Zou et al.

JOURNAL OF GASTROINTESTINAL ONCOLOGY (2020)

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Article Ophthalmology

Photodynamic Therapy for Chorioretinal Diseases: A Practical Approach

Elon H. C. van Dijk et al.

OPHTHALMOLOGY AND THERAPY (2020)

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Article Gastroenterology & Hepatology

Two cases of bile duct carcinoma patients who underwent the photodynamic therapy using talaporfin sodium (Laserphyrin)

Atsushi Nanashima et al.

CLINICAL JOURNAL OF GASTROENTEROLOGY (2020)

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Review Surgery

Photodynamic Therapy for the Treatment of Glioblastoma

Samuel W. Cramer et al.

FRONTIERS IN SURGERY (2020)

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Review Medicine, Research & Experimental

Versatile Nanoplatforms with enhanced Photodynamic Therapy: Designs and Applications

Kai Yan et al.

THERANOSTICS (2020)

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Article Materials Science, Biomaterials

Near-infrared photothermal liposomal nanoantagonists for amplified cancer photodynamic therapy

Haitao Sun et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Review Chemistry, Multidisciplinary

Advanced Photosensitizer Activation Strategies for Smarter Photodynamic Therapy Beacons

Benjamin M. d Luby et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Oncology

Effect of photodynamic therapy by 810 and 940 nm diode laser on Herpes Simplex Virus 1: An in vitro study

Mahsa Alavi Namvar et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2019)

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Article Engineering, Environmental

Self-assembled zinc phthalocyanine nanoparticles as excellent photothermal/photodynamic synergistic agent for antitumor treatment

Zhao Wang et al.

CHEMICAL ENGINEERING JOURNAL (2019)

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Review Chemistry, Multidisciplinary

Current state of the nanoscale delivery systems for temoporfin-based photodynamic therapy: Advanced delivery strategies

Ilya Yakavets et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Review Engineering, Biomedical

Photosensitizers for Photodynamic Therapy

Minhuan Lan et al.

ADVANCED HEALTHCARE MATERIALS (2019)

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Review Biochemistry & Molecular Biology

Application of Porphyrins in Antibacterial Photodynamic Therapy

Bamidele M. Amos-Tautua et al.

MOLECULES (2019)

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Article Biochemistry & Molecular Biology

Anticancer Photodynamic Therapy Properties of Sulfur-Doped Graphene Quantum Dot and Methylene Blue Preparations in MCF-7 Breast Cancer Cell Culture

Jerry D. Monroe et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2019)

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Article Engineering, Biomedical

Gold-caged copolymer nanoparticles as multimodal synergistic photodynamic/photothermal/chemotherapy platform against lethality androgen-resistant prostate cancer

Qi Wang et al.

BIOMATERIALS (2019)

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Review Oncology

Photodynamic therapy in superficial basal cell carcinoma treatment

Itajai Oliveira de Albuquerque et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2019)

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Article Chemistry, Multidisciplinary

Polymeric Encapsulation of Novel Homoleptic Bis(dipyrrinato) Zinc(II) Complexes with Long Lifetimes for Applications as Photodynamic Therapy Photosensitisers

Johannes Karges et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Article Chemistry, Applied

Chitosan-coated liposomes to stabilize and enhance transdermal delivery of indocyanine green for photodynamic therapy of melanoma

Eun-Hye Lee et al.

CARBOHYDRATE POLYMERS (2019)

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Article Engineering, Biomedical

A dual-targeted hyaluronic acid-gold nanorod platform with triple-stimuli responsiveness for photodynamic/photothermal therapy of breast cancer

Weijun Xu et al.

ACTA BIOMATERIALIA (2019)

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Article Respiratory System

Outcomes of patients with advanced non-small cell lung cancer and airway obstruction treated with photodynamic therapy and non-photodynamic therapy ablation modalities

Ravishankar Jayadevappa et al.

JOURNAL OF THORACIC DISEASE (2019)

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Review Food Science & Technology

Perspectives and Trends in the Application of Photodynamic Inactivation for Microbiological Food Safety

Vinayak S. Ghate et al.

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2019)

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Review Chemistry, Inorganic & Nuclear

Photosensitization and controlled photosensitization with BODIPY dyes

Abdurrahman Turksoy et al.

COORDINATION CHEMISTRY REVIEWS (2019)

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Review Engineering, Chemical

Carbon-based materials for photodynamic therapy: A mini-review

Di Lu et al.

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING (2019)

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Review Chemistry, Applied

Alternative strategies for fighting multidrug resistant bacterial infections

Paulina Podgoreanu et al.

BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY (2019)

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Review Dermatology

Clinical utility of daylight photodynamic therapy in the treatment of actinic keratosis - a review of the literature

Mimi Nguyen et al.

CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY (2019)

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Article Chemistry, Multidisciplinary

Red emitting conjugated polymer based nanophotosensitizers for selectively targeted two- photon excitation imaging guided photodynamic therapy

Xiangyan Duan et al.

NANOSCALE (2019)

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Article Medicine, Research & Experimental

Core-shell metal-organic frameworks with fluorescence switch to trigger an enhanced photodynamic therapy

Yuan Liu et al.

THERANOSTICS (2019)

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Article Chemistry, Multidisciplinary

Nanozyme Decorated Metal-Organic Frameworks for Enhanced Photodynamic Therapy

Yan Zhang et al.

ACS NANO (2018)

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Review Medicine, Research & Experimental

Photodynamic therapy - mechanisms, photosensitizers and combinations

Stanislaw Kwiatkowski et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

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Review Chemistry, Multidisciplinary

Supramolecular photosensitizers rejuvenate photodynamic therapy

Xingshu Li et al.

CHEMICAL SOCIETY REVIEWS (2018)

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Review Biochemistry & Molecular Biology

Recent Progress in Metal-Based Nanoparticles Mediated Photodynamic Therapy

Jingyao Sun et al.

MOLECULES (2018)

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Article Biochemistry & Molecular Biology

Fullerenes as photosensitizers in photodynamic therapy: pros and cons

Michael R. Hamblin

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2018)

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Article Dermatology

Effectiveness of photodynamic therapy in Bowen's disease: a retrospective observational study in 423 lesions

O. Zaar et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2017)

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Article Immunology

Advanced strategies in immune Modulation of cancer Using Lipid-Based Nanoparticles

Shoshy Mizrahy et al.

FRONTIERS IN IMMUNOLOGY (2017)

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Review Materials Science, Biomaterials

Advanced smart-photosensitizers for more effective cancer treatment

Wooram Park et al.

BIOMATERIALS SCIENCE (2017)

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Review Surgery

Nanoparticles for Advanced Photodynamic Therapy of Cancer

Heidi Abrahamse et al.

PHOTOMEDICINE AND LASER SURGERY (2017)

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Review Chemistry, Multidisciplinary

The development of anticancer ruthenium(II) complexes: from single molecule compounds to nanomaterials

Leli Zeng et al.

CHEMICAL SOCIETY REVIEWS (2017)

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Review Oncology

Photodynamic therapy: Inception to application in breast cancer

S. M. Banerjee et al.

BREAST (2017)

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Review Biochemistry & Molecular Biology

New photosensitizers for photodynamic therapy

Heidi Abrahamse et al.

BIOCHEMICAL JOURNAL (2016)

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Article Dermatology

A brief report on the history of phototherapy

Andrzej Grzybowski et al.

CLINICS IN DERMATOLOGY (2016)

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Review Biochemistry & Molecular Biology

Nanotechnology-Based Drug Delivery Systems for Photodynamic Therapy of Cancer: A Review

Giovana Maria Fioramonti Calixto et al.

MOLECULES (2016)

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Article Biochemistry & Molecular Biology

Photodynamic and Antibiotic Therapy in Combination to Fight Biofilms and Resistant Surface Bacterial Infections

Federica Barra et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

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Article Engineering, Biomedical

Effect of methylene blue-mediated photodynamic therapy for treatment of basal cell carcinoma

Nevien A. Samy et al.

LASERS IN MEDICAL SCIENCE (2015)

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Article Biochemistry & Molecular Biology

Methylene blue covalently loaded polyacrylamide nanoparticles for enhanced tumor-targeted photodynamic therapy

Ming Qin et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2011)

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Article Oncology

Cell Death Pathways in Photodynamic Therapy of Cancer

Pawel Mroz et al.

Cancers (2011)

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Article Biochemistry & Molecular Biology

Encapsulation of methylene blue in polyacrylamide nanoparticle platforms protects its photodynamic effectiveness

Wei Tang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

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Review Biotechnology & Applied Microbiology

Nanoparticles as vehicles for delivery of photodynamic therapy agents

Denise Bechet et al.

TRENDS IN BIOTECHNOLOGY (2008)

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Article Biochemistry & Molecular Biology

Comparative characterization of the efficiency and cellular pharmacokinetics of Foscan-® and Foslip®-based photodynamic treatment in human biliary tract cancer cell lines

Tobias Kiesslich et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2007)

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Article Ophthalmology

Choroidal vascular remodelling in central serous chorioretinopathy after indocyanine green guided photodynamic therapy with verteporfin: a novel treatment at the primary disease level

WM Chan et al.

BRITISH JOURNAL OF OPHTHALMOLOGY (2003)

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Article Ophthalmology

Photodynamic therapy for chronic central serous chorioretinopathy

FC Piccolino et al.

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2003)

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