4.6 Article

Integrated Collection of Stem Cell Bank Data, a Data Portal for Standardized Stem Cell Information

期刊

STEM CELL REPORTS
卷 16, 期 4, 页码 997-1005

出版社

CELL PRESS
DOI: 10.1016/j.stemcr.2021.02.014

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资金

  1. Core Center for iPS Cell Research, Research Center Network for Realization of Regenerative Medicine [16bm0104001h0004]
  2. Formulation of Regenerative Medicine National Consortium [19bk0204001h0004, 19bk0204001s0104]
  3. Japan Agency for Medical Research and Development (AMED)
  4. German Academic Exchange Service (DAAD) PPP grant

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ICSCB is an integrated database search portal for stem cell line information, based on standardized data items and terms of the MIACARM framework. It can retrieve over 16,000 cell lines from four major data resources in Europe, Japan, and the United States, and is automatically updated to provide the latest cell line information.
The past decade has witnessed an extremely rapid increase in the number of newly established stem cell lines. However, due to the lack of a standardized format, data exchange among stem cell line resources has been challenging, and no system can search all stem cell lines across resources worldwide. To solve this problem, we have developed the Integrated Collection of Stem Cell Bank data (ICSCB) (http:// icscb.stemcellinformatics.org/), the largest database search portal for stem cell line information, based on the standardized data items and terms of the MIACARM framework. Currently, ICSCB can retrieve >16,000 cell lines from four major data resources in Europe, Japan, and the United States. ICSCB is automatically updated to provide the latest cell line information, and its integrative search helps users collect cell line information for over 1,000 diseases, including many rare diseases worldwide, which has been a formidable task, thereby distinguishing itself from other database search portals.

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