4.7 Review

Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design

期刊

NANOMATERIALS
卷 11, 期 4, 页码 -

出版社

MDPI
DOI: 10.3390/nano11041001

关键词

inorganic nanoparticles; surface chemistry; peptide and proteins; monolayers; nanozyme; bioorthogonal catalysis; bacterial biofilm; tumors; stimuli-responsive; drug delivery

资金

  1. National Institutes of Health [DK121351, AI134770, EB022641]

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This review discusses the methods of functionalizing nanoparticles with small organic ligands to engineer NPs for nanobiology and nanomedicine.
Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with small organic ligands (Mw < 1000), providing insight into how organic synthesis can be used to engineer NPs for nanobiology and nanomedicine.

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