Degradation of Titanium Sintered with Magnesium: Effect of Hydrogen Uptake

Multifunctional materials based on a combination of permanent and degradable metals open new perspectives for medical implants combining osseoconductivity and drug-delivery functions which can significantly decrease the number of implants' revision. In this work, hybrid magnesium-titanium materials were produced via sintering, and the properties of the permanent titanium component before and after the degradation of the temporary magnesium part were evaluated. The changes of chemical composition and mechanical parameters were determined. Loading of hydrogen into the titanium part at room temperature was observed, which deteriorated the mechanical characteristics but could also simultaneously improve the biocompatibility of the permanent titanium implant. The control of degradation of the magnesium part and the modification of the titanium part are required for the development of partly degradable hybrid implants.

Automated summary

Multifunctional materials based on a combination of permanent and degradable metals were investigated for medical implants with osseoconductivity and drug-delivery functions. The study showed that controlling the degradation of the magnesium part and modifying the titanium part were necessary for developing partly degradable hybrid implants.