期刊
FRONTIERS IN PHYSIOLOGY
卷 12, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphys.2021.650696
关键词
blood pressure; cardiac pre-load; myocardial contractility; echocardiography; tissue Doppler
类别
资金
- University of Cagliari
- Regione Autonoma della Sardegna [7/2007]
The study showed that performing mild exercise in acute hypoxia does not impair myocardial systolic or diastolic functions, but rather enhances cardiac functions. There were no significant effects on left ventricular volumes, while exercise promoted cardiac systolic and early diastolic functions.
Acute hypoxia (AH) is a challenge to the homeostasis of the cardiovascular system, especially during exercise. Research in this area is scarce. We aimed to ascertain whether echocardiographic, Doppler, and tissue Doppler measures were able to detect changes in systolic and diastolic functions during the recovery after mild exercise in AH. Twelve healthy males (age 33.5 +/- 4.8 years) completed a cardiopulmonary test on an electromagnetically braked cycle-ergometer to determine their maximum workload (W-max). On separate days, participants performed randomly assigned two exercise sessions consisting in 3 min pedalling at 30% of W-max: (1) one test was conducted in normoxia (NORMO) and (2) one in normobaric hypoxia with FiO(2) set to 13.5% (HYPO). Hemodynamics were assessed with an echocardiographic system. The main result was that the HYPO session increased parameters related to myocardial contractility such as pre-ejection period and systolic myocardial velocity with respect to the NORMO test. Moreover, the HYPO test enhanced early transmitral filling peak velocities. No effects were detected for left ventricular volumes, as end-diastolic, end-systolic, and stroke volume were similar between the NORMO and the HYPO test. Results of the present investigation support the hypothesis that a brief, mild exercise bout in acute normobaric hypoxia does not impair systolic or diastolic functions. Rather, it appears that stroke volume is well preserved and that systolic and early diastolic functions are enhanced by exercise in hypoxia.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据