4.7 Article

Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist S6 Stimulates Insulin Secretion From Rat Islets

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

lIon Channels of the Islets in Type 2 Diabetes

David A. Jacobson et al.

JOURNAL OF MOLECULAR BIOLOGY (2020)

Review Physiology

PANCREATIC beta-CELL ELECTRICAL ACTIVITY AND INSULIN SECRETION: OF MICE AND MEN

Patrik Rorsman et al.

PHYSIOLOGICAL REVIEWS (2018)

Editorial Material Chemistry, Medicinal

CETSA: a target engagement assay with potential to transform drug discovery

Annika Jenmalm Jensen et al.

FUTURE MEDICINAL CHEMISTRY (2015)

Article Biochemical Research Methods

The cellular thermal shift assay for evaluating drug target interactions in cells

Rozbeh Jafari et al.

NATURE PROTOCOLS (2014)

Review Endocrinology & Metabolism

GLP-1 receptor activated insulin secretion from pancreatic ss-cells: mechanism and glucose dependence

A. R. Meloni et al.

DIABETES OBESITY & METABOLISM (2013)

Article Chemistry, Analytical

Application of Bio-Layer Interferometry for the analysis of protein/liposome interactions

Jakob Wallner et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2013)

Article Medicine, General & Internal

The rationale for combining GLP-1 receptor agonists with basal insulin

Neale D. Cohen et al.

MEDICAL JOURNAL OF AUSTRALIA (2013)

Article Multidisciplinary Sciences

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Daniel Martinez Molina et al.

SCIENCE (2013)

Review Endocrinology & Metabolism

Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor

Francis S. Willard et al.

EXPERIMENTAL DIABETES RESEARCH (2012)

Article Gastroenterology & Hepatology

Pancreatitis, Pancreatic, and Thyroid Cancer With Glucagon-Like Peptide-1-Based Therapies

Michael Elashoff et al.

GASTROENTEROLOGY (2011)

Review Pharmacology & Pharmacy

Pharmacophore modeling and applications in drug discovery: challenges and recent advances

Sheng-Yong Yang

DRUG DISCOVERY TODAY (2010)

Article Endocrinology & Metabolism

Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics) - preclinical and clinical results

Sten Madsbad

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2009)

Article Medicine, General & Internal

Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists

K. B. Hansen et al.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2009)

Article Biochemistry & Molecular Biology

Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists

Fu Lin et al.

JOURNAL OF MOLECULAR MODELING (2009)

Article Biochemical Research Methods

Cell-based assays in GPCR drug discovery

Sandra Siehler

Biotechnology Journal (2008)

Review Chemistry, Medicinal

Generation of a set of simple, interpretable ADMET rules of thumb

M. Paul Gleeson

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Review Gastroenterology & Hepatology

Biology of incretins: GLP-1 and GIP

Laurie L. Baggio et al.

GASTROENTEROLOGY (2007)

Article Biochemistry & Molecular Biology

A marriage made in torsional space: using GALAHAD models to drive pharmacophore multiplet searches

Jennifer K. Shepphird et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2006)

Article Biochemistry & Molecular Biology

GALAHAD: 1. Pharmacophore identification by hypermolecular alignment of ligands in 3D

Nicola J. Richmond et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2006)

Article Biochemical Research Methods

Multiplexed G-protein-coupled receptor Ca2+ flux assays for high-throughput screening

JJ Miret et al.

JOURNAL OF BIOMOLECULAR SCREENING (2005)

Article Biochemical Research Methods

An offline-addition format for identifying GPCR modulators by screening 384-well mixed compounds in the FLIPR

SM Gopalakrishnan et al.

JOURNAL OF BIOMOLECULAR SCREENING (2005)

Article Chemistry, Medicinal

ZINC - A free database of commercially available compounds for virtual screening

JJ Irwin et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2005)