4.7 Review

Advances of Fibroblast Growth Factor/Receptor Signaling Pathway in Hepatocellular Carcinoma and its Pharmacotherapeutic Targets

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Review Pharmacology & Pharmacy

Fibroblast growth factor (FGF)-21 based therapies: A magic bullet for nonalcoholic fatty liver disease (NAFLD)?

Michael Ritchie et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)

Review Gastroenterology & Hepatology

Tumour evolution in hepatocellular carcinoma

Amanda J. Craig et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Editorial Material Oncology

Benefit from pemigatinib in cholangiocarcinoma

Diana Romero

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Article Biochemistry & Molecular Biology

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

Zefang Tang et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Cell Biology

FGF19-FGFR4 Signaling in Hepatocellular Carcinoma

Aroosha Raja et al.

Review Biochemistry & Molecular Biology

The role of the fibroblast growth factor family in bone-related diseases

Jicheng Wang et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2019)

Article Biotechnology & Applied Microbiology

FGFR2-BICC1: A Subtype Of FGFR2 Oncogenic Fusion Variant In Cholangiocarcinoma And The Response To Sorafenib

Xihui Ying et al.

ONCOTARGETS AND THERAPY (2019)

Review Gastroenterology & Hepatology

Systemic Therapy for Advanced Hepatocellular Carcinoma: An Update of a Rapidly Evolving Field

Iliana Doycheva et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2019)

Article Oncology

Up-regulation of FGF15/19 signaling promotes hepatocellular carcinoma in the background of fatty liver

Guozhen Cui et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)

Article Endocrinology & Metabolism

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity

Archita Agrawal et al.

MOLECULAR METABOLISM (2018)

Review Biochemistry & Molecular Biology

Structural Alterations in Human Fibroblast Growth Factor Receptors in Carcinogenesis

D. S. Mikhaylenko et al.

BIOCHEMISTRY-MOSCOW (2018)

Article Oncology

Lenvatinib as a therapy for unresectable hepatocellular carcinoma

Andrea Spallanzani et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2018)

Review Pharmacology & Pharmacy

Tivantinib for the treatment of hepatocellular carcinoma

Jan Best et al.

EXPERT OPINION ON PHARMACOTHERAPY (2017)

Article Oncology

FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

Lixia Gao et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)

Article Biochemistry & Molecular Biology

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

Zefang Tang et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Multidisciplinary Sciences

Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis

Mei Zhou et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Rush to the fire: FGF21 extinguishes metabolic stress, metaflammation and tissue damage

Yongde Luo et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2017)

Article Gastroenterology & Hepatology

Fibroblast Growth Factor 15/19 in Hepatocarcinogenesis

Gloria Alvarez-Sola et al.

DIGESTIVE DISEASES (2017)

Article Biotechnology & Applied Microbiology

Expression of functional recombinant human fibroblast growth factor 8b and its protective effects on MPP+-lesioned PC12 cells

Nazi Chen et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2016)

Article Oncology

FGF18 as a potential biomarker in serous and mucinous ovarian tumors

Saba El-Gendi et al.

TUMOR BIOLOGY (2016)

Review Medicine, Research & Experimental

FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review)

Masaru Katoh

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)

Article Multidisciplinary Sciences

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Gunter Schumann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Cell Biology

Roles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and Disease

Nobuyuki Itoh et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2016)

Article Pharmacology & Pharmacy

Molecular Targeted Therapy for Hepatocellular Carcinoma: Present Status and Future Directions

Kyung-Ju Choi et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2015)

Review Oncology

Targeting FGFR Signaling in Cancer

Mehdi Touat et al.

CLINICAL CANCER RESEARCH (2015)

Article Gastroenterology & Hepatology

Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers

Willscott E. Naugler et al.

GASTROENTEROLOGY (2015)

Article Oncology

Erratum: Advances in targeted therapies for hepatocellular carcinoma in the genomic era

Josep M. Llovet et al.

Nature Reviews Clinical Oncology (2015)

Article Oncology

Polymorphisms of FGFR1 in HBV-related hepatocellular carcinoma

Haiyang Xie et al.

TUMOR BIOLOGY (2015)

Review Developmental Biology

The Fibroblast Growth Factor signaling pathway

David M. Ornitz et al.

WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2015)

Review Pharmacology & Pharmacy

Targeting fibroblast growth factor 19 in liver disease: a potential biomarker and therapeutic target

Wen-Yue Liu et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2015)

Article Oncology

Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development

Iker Uriarte et al.

INTERNATIONAL JOURNAL OF CANCER (2015)

Article Veterinary Sciences

Fibroblast Growth Factor-5 Participates in the Progression of Hepatic Fibrosis

Hiromi Hanaka et al.

EXPERIMENTAL ANIMALS (2014)

Article Gastroenterology & Hepatology

Fibroblast Growth Factor Signaling in Liver Carcinogenesis

Dalbir S. Sandhu et al.

HEPATOLOGY (2014)

Article Urology & Nephrology

A short story of Klotho and FGF23: a deuce of dark side or the savior?

F. Fevzi Ersoy

INTERNATIONAL UROLOGY AND NEPHROLOGY (2014)

Review Chemistry, Medicinal

FGF Receptors: Cancer Biology and Therapeutics

Masaru Katoh et al.

MEDICINAL RESEARCH REVIEWS (2014)

Article Biochemistry & Molecular Biology

Downregulation of microRNA-214 and overexpression of FGFR-1 contribute to hepatocellular carcinoma metastasis

Jian Wang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Article Gastroenterology & Hepatology

Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress

Chaofeng Yang et al.

BMC GASTROENTEROLOGY (2013)

Article Biochemistry & Molecular Biology

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

Jianjiong Gao et al.

SCIENCE SIGNALING (2013)

Article Gastroenterology & Hepatology

Clinical Trials in Hepatocellular Carcinoma: An Update

Ying-Chun Shen et al.

Liver Cancer (2013)

Article Biochemistry & Molecular Biology

Association between fibroblast growth factor receptor 4 polymorphisms and risk of hepatocellular carcinoma

Yuan Yang et al.

MOLECULAR CARCINOGENESIS (2012)

Article Multidisciplinary Sciences

Targeting FGFR4 Inhibits Hepatocellular Carcinoma in Preclinical Mouse Models

Dorothy M. French et al.

PLOS ONE (2012)

Review Oncology

Emerging Signaling Pathways in Hepatocellular Carcinoma

Agrin Moeini et al.

LIVER CANCER (2012)

Review Biochemistry & Molecular Biology

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

Nobuyuki Itoh et al.

JOURNAL OF BIOCHEMISTRY (2011)

Review Developmental Biology

Extending the Family Table: Insights From Beyond Vertebrates Into the Regulation of Embryonic Development by FGFs

Sarah Tulin et al.

BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2010)

Article Oncology

Pancreatic Endocrine Tumors: Expression Profiling Evidences a Role for AKT-mTOR Pathway

Edoardo Missiaglia et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

Article Endocrinology & Metabolism

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

Klementina Fon Tacer et al.

MOLECULAR ENDOCRINOLOGY (2010)

Article Cell & Tissue Engineering

Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration

Ye-Rang Yun et al.

Journal of Tissue Engineering (2010)

Review Oncology

Fibroblast growth factor signalling: from development to cancer

Nicholas Turner et al.

NATURE REVIEWS CANCER (2010)

Review Biotechnology & Applied Microbiology

The FGF family: biology, pathophysiology and therapy

Andrew Beenken et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Cell Biology

FGF-21/FGF-21 receptor interaction and activation is determined by βKlotho

Alexei Kharitonenkov et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2008)

Review Anatomy & Morphology

Functional evolutionary history of the mouse Fgf gene family

Nobuyuki Itoh et al.

DEVELOPMENTAL DYNAMICS (2008)

Article Oncology

FGF18 in colorectal tumour cells: autocrine and paracrine effects

Gudrun Sonvilla et al.

CARCINOGENESIS (2008)

Article Biochemistry & Molecular Biology

Liver-specific activities of FGF19 require Klotho beta

Benjamin C. Lin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

Regina Goetz et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Direct interactions of Runx2 and canonical Wnt signaling induce FGF18

Martina I. Reinhold et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Itaru Urakawa et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Identification of a hormonal basis for gallbladder filling

Mihwa Choi et al.

NATURE MEDICINE (2006)

Review Biochemistry & Molecular Biology

Receptor specificity of the fibroblast growth factor family - The complete mammalian FGF family

Xiuqin Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Gastroenterology & Hepatology

Management of hepatoceullular carcinoma

J Bruix et al.

HEPATOLOGY (2005)

Review Biochemistry & Molecular Biology

Cellular signaling by fibroblast growth factor receptors

VP Eswarakumar et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2005)

Review Genetics & Heredity

Evolution of the Fgf and Fgfr gene families

N Itoh et al.

TRENDS IN GENETICS (2004)

Article Oncology

Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling

Y Midorikawa et al.

INTERNATIONAL JOURNAL OF CANCER (2003)