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DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2010)
Hippocampal neurovascular and hypothalamic-pituitary-adrenal axis alterations in spontaneously type 2 diabetic GK rats
Juan Beauquis et al.
EXPERIMENTAL NEUROLOGY (2010)
Psychological correlates of childhood obesity
J. J. Puder et al.
INTERNATIONAL JOURNAL OF OBESITY (2010)
Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease A Randomized Trial
Joseph F. Quinn et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
Being Overweight in Midlife Is Associated With Lower Cognitive Ability and Steeper Cognitive Decline in Late Life
Anna Dahl et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
Cameron R. Stewart et al.
NATURE IMMUNOLOGY (2010)
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-beta Levels in a Mouse Model of Alzheimer's Disease
Patricia Spilman et al.
PLOS ONE (2010)
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease
Antonella Caccamo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Obesity and vulnerability of the CNS
Annadora J. Bruce-Keller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Blocked Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3α/β Impairs In Vivo Neural Precursor Cell Proliferation
Tae-Yeon Eom et al.
BIOLOGICAL PSYCHIATRY (2009)
Midlife Serum Cholesterol and Increased Risk of Alzheimer's and Vascular Dementia Three Decades Later
Alina Solomon et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2009)
Neuronal IGF-1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer's disease
Susanna Freude et al.
FASEB JOURNAL (2009)
Brain-Derived Neurotrophic Factor Levels in Alzheimer's Disease
Sid E. O'Bryant et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Oxysterols and neurodegenerative diseases
Ingemar Bjorkhem et al.
MOLECULAR ASPECTS OF MEDICINE (2009)
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial
Samuel T. Henderson et al.
NUTRITION & METABOLISM (2009)
A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation
C. D. Clelland et al.
SCIENCE (2009)
Cross-Talk between PPAR gamma and Insulin Signaling and Modulation of Insulin Sensitivity
Anna Leonardini et al.
PPAR RESEARCH (2009)
Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)
ARCHIVES OF NEUROLOGY (2008)
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
Patrice D. Cani et al.
DIABETES (2008)
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
J. de Heer et al.
DIABETOLOGIA (2008)
GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
Victor A. Gault et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse
J. Beauquis et al.
EXPERIMENTAL NEUROLOGY (2008)
Increased expression of the γ-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury
Yasmine Nadler et al.
GLIA (2008)
Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): Cyclooxygenase (COX) inhibition and beyond
P. N. Praveen Rao et al.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES (2008)
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
Alexis M. Stranahan et al.
NATURE NEUROSCIENCE (2008)
Hyperglycemia not hypoglycemia alters neuronal dendrites and impairs spatial memory
John I. Malone et al.
PEDIATRIC DIABETES (2008)
Microglial activation in the hippocampus of hypercholesterolemic rabbits occurs independent of increased amyloid production
Qing-Shan Xue et al.
JOURNAL OF NEUROINFLAMMATION (2007)
Adult hippocampal neurogenesis and aging
Friederike Klempin et al.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2007)
C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
M. Poggi et al.
DIABETOLOGIA (2007)
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
Claus M. Larsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
UP inhibits LTD in the hippocampus via regulation of GSK3β
Stephane Peineau et al.
NEURON (2007)
Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes
Cindy X. Zhang-Gandhi et al.
JOURNAL OF NEUROIMMUNOLOGY (2007)
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
Richard S. Jope et al.
NEUROCHEMICAL RESEARCH (2007)
An obesity-associated gut microbiome with increased capacity for energy harvest
Peter J. Turnbaugh et al.
NATURE (2006)
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
Stephen W. Scheff et al.
NEUROBIOLOGY OF AGING (2006)
ω-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease:: OmegAD study -: A randomized double-blind trial
Yvonne Freund-Levi et al.
ARCHIVES OF NEUROLOGY (2006)
Opposing activities protect against age-onset proteotoxicity
Ehud Cohen et al.
SCIENCE (2006)
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
M. E. Risner et al.
PHARMACOGENOMICS JOURNAL (2006)
mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging
MG Frank et al.
NEUROBIOLOGY OF AGING (2006)
Brain cholesterol turnover required for geranylgeraniol production and learning in mice
TJ Kotti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Improving metabolic control leads to better working memory in adults with type 2 diabetes
CM Ryan et al.
DIABETES CARE (2006)
Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease:: review and hypothesis
WQ Qiu et al.
NEUROBIOLOGY OF AGING (2006)
Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells
S Aleffi et al.
HEPATOLOGY (2005)
Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease
SY Peng et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: The InCHIANTI study
R Elosua et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2005)
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
RJ Griffin et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Peroxisome proliferator-activated receptor γ is expressed in hippocampal neurons and its activation prevents β-amyloid neurodegeneration:: role of Wnt signaling
NC Inestrosa et al.
EXPERIMENTAL CELL RESEARCH (2005)
Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice
Michael T. Heneka et al.
JOURNAL OF NEUROINFLAMMATION (2005)
Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease β-secretase (BACE-1)
I Blasko et al.
JOURNAL OF NEURAL TRANSMISSION (2004)
Long-term accumulation of amyloid-β, β-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma
XH Chen et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Intranasal insulin improves memory in humans
C Benedict et al.
PSYCHONEUROENDOCRINOLOGY (2004)
Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets
L Farilla et al.
ENDOCRINOLOGY (2003)
Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies
M Etminan et al.
BMJ-BRITISH MEDICAL JOURNAL (2003)
Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression - A randomized controlled trial
PS Aisen et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)
Astrocytosis, microgliosis, metallothionein-I-II and amyloid expression in high cholesterol-fed rabbits
Paolo Zatta et al.
JOURNAL OF ALZHEIMERS DISEASE (2002)
Role of AMP-activated protein kinase in mechanism of metformin action
GC Zhou et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
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