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Genetic Technologies for Sustainable Management of Insect Pests and Disease Vectors

期刊

SUSTAINABILITY
卷 13, 期 10, 页码 -

出版社

MDPI
DOI: 10.3390/su13105653

关键词

sustainability; genetic control; disease vectors; genome editing; gene drive

资金

  1. Bill and Melinda Gates Foundation [LCII PSC656]
  2. School of Life Sciences at Keele University
  3. Defense Advanced Research Projects Agency Safe Genes program (DAPRA) [HR0011-17-2-0042]

向作者/读者索取更多资源

Recent advancements in genetic and genome editing research, particularly the discovery of new molecular tools like CRISPR, have enabled precise site-specific genome modifications with unprecedented ease, revolutionizing the field of genetic engineering. These technologies have a wide range of applications, including novel methods for vector and pest insect control, with the ability to impose varying levels of impact on targeted populations based on genetic makeup and engineering. The review highlights the molecular mechanisms and performance of recent genetic control innovations, emphasizing the sustainability potentials of such interventions.
Recent advancements in genetic and genome editing research, augmented by the discovery of new molecular tools such as CRISPR, have revolutionised the field of genetic engineering by enabling precise site-specific genome modifications with unprecedented ease. These technologies have found a vast range of applications, including the development of novel methods for the control of vector and pest insects. According to their genetic makeup and engineering, these tools can be tuned to impose different grades of impact on the targeted populations. Here, we review some of the most recent genetic control innovations under development, describing their molecular mechanisms and performance, highlighting the sustainability potentials of such interventions.

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