期刊
POLYMERS
卷 13, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/polym13101608
关键词
wound treatment; patches; foams; foaming process; supercritical fluids
This work provides an overview of wound types, their definition, classification, and dressing treatments, with a focus on natural and synthetic polymeric wound dressings. Various materials such as hydrocolloids, polyurethane, and alginate patches are discussed for wound treatment, along with the use of foams. Case studies and in vivo tests are presented to identify the real applications of produced foams.
This work represents an overview on types of wounds according to their definition, classification and dressing treatments. Natural and synthetic polymeric wound dressings types have been analyzed, providing a historical overview, from ancient to modern times. Currently, there is a wide choice of materials for the treatment of wounds, such as hydrocolloids, polyurethane and alginate patches, wafers, hydrogels and semi-permeable film dressings. These systems are often loaded with drugs such as antibiotics for the simultaneous delivery of drugs to prevent or cure infections caused by the exposition of blood vessel to open air. Among the presented techniques, a focus on foams has been provided, describing the most diffused branded products and their chemical, physical, biological and mechanical properties. Conventional and high-pressure methods for the production of foams for wound dressing are also analyzed in this work, with a proposed comparison in terms of process steps, efficiency and removal of solvent residue. Case studies, in vivo tests and models have been reported to identify the real applications of the produced foams.
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