期刊
EUROPEAN NEUROLOGY
卷 76, 期 5-6, 页码 195-201出版社
KARGER
DOI: 10.1159/000450604
关键词
Acute ischemic stroke; Low-density lipoprotein cholesterol; Outcome; Risk factors
资金
- Tianjin Health Bureau of Science and Technology Fund Key Projects [KY12, 2013KG120]
- Tianjin Huanhu Hospital
Studies show inconsistent associations between low-density lipoprotein cholesterol (LDL-C) and stroke outcome. We assessed these associations among patients with first-ever acute ischemic stroke (AIS) in China. Patients with first-ever AIS were categorized into 3 groups: normal LDL, marginally elevated LDL and high LDL - according to the LDL-C values on admission. The outcome measures that were investigated in each group included mortality, dependence and recurrence of vascular events. Patients with high LDL-C had higher mortality rates than did those with normal LDL-C at both 12 and 36 months, but this difference disappeared after adjustment for covariates. There was no difference between groups in mortality at 3 months and dependency or recurrence at 3, 12 or 36 months. LDL-C level was associated with long-term mortality after stroke, but was not an independent prognostic factor. (C) 2016 S. Karger AG, Basel
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