4.7 Review

Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D2-Serotonin 5-HT1A Heteromers

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Materials Science, Biomaterials

Topical formulations containing aptamer-functionalized nanocapsules loaded with 5-fluorouracil - An innovative concept for the skin cancer therapy

Delia Mihaela Rata et al.

Summary: The new topical gel formulations containing AS1411 aptamer-functionalized polymeric nanocapsules loaded with an antitumoral drug showed promising potential for skin cancer treatment. Characterization tests including rheological, permeation, hemolysis, skin irritation, cytotoxicity and in vivo tests demonstrated the safety and effectiveness of the gel formulations. Nanoencapsulation of 5-Fluorouracil enhanced its permeability and cytotoxicity, making it an attractive option for skin cancer therapy.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Review Pharmacology & Pharmacy

Nanoparticles as carriers for drug delivery of macromolecules across the blood-brain barrier

Giovanni Tosi et al.

EXPERT OPINION ON DRUG DELIVERY (2020)

Review Biochemistry & Molecular Biology

Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections

Arturo Sanchez et al.

MOLECULES (2020)

Article Chemistry, Multidisciplinary

Use of Solid Lipid Nanoparticles for the Treatment of Acute Acoustic Stress-Induced Cochlea Damage

Ningning Wang et al.

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2020)

Article Behavioral Sciences

G protein-coupled receptor heteromers are key players in substance use disorder

Lyes Derouiche et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2019)

Article Biotechnology & Applied Microbiology

In vitro and in vivo characterization of pharmaceutical nanocarriers used for drug delivery

Akhlesh K. Jain et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

Review Pharmacology & Pharmacy

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

Nathan D. Donahue et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Materials Science, Biomaterials

In vitro behaviour of aptamer-functionalized polymeric nanocapsules loaded with 5-fluorouracil for targeted therapy

Delia Mihaela Rata et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Engineering, Biomedical

CDI cross-linked -cyclodextrin nanosponges of paliperidone: synthesis and physicochemical characterization

Atul P. Sherje et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2019)

Article Multidisciplinary Sciences

In vivo evaluation of safety, biodistribution and pharmacokinetics of laser-synthesized gold nanoparticles

Anne-Laure Bailly et al.

SCIENTIFIC REPORTS (2019)

Review Neurosciences

Transcytosis to Cross the Blood Brain Barrier, New Advancements and Challenges

Victor M. Pulgar

FRONTIERS IN NEUROSCIENCE (2019)

Article Pharmacology & Pharmacy

DoE based Olanzapine loaded poly-caprolactone nanoparticles decreases extrapyramidal effects in rodent model

Emil Joseph et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)

Review Pharmacology & Pharmacy

The challenges of oral drug delivery via nanocarriers

Jonas Reinholz et al.

DRUG DELIVERY (2018)

Review Pharmacology & Pharmacy

Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine

Domenico De Berardis et al.

THERAPEUTIC ADVANCES IN DRUG SAFETY (2018)

Article Biophysics

The interaction of clozapine loaded nanocapsules with the hCMEC/D3 cells - In vitro model of blood brain barrier

Sylwia Lukasiewicz et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

Review Pharmacology & Pharmacy

G Protein-Coupled Receptor Heteromers

Ivone Gomes et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)

Article Biophysics

Encapsulation of clozapine in polymeric nanocapsules and its biological effects

Sylwia Lukasiewicz et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2016)

Review Chemistry, Medicinal

Delivery of Antipsychotics with Nanoparticles

Yuan Sun et al.

DRUG DEVELOPMENT RESEARCH (2016)

Article Biochemistry & Molecular Biology

Dopamine D2 and serotonin 5-HT1A receptor interaction in the context of the effects of antipsychotics - in vitro studies

Sylwia Lukasiewicz et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Article Nanoscience & Nanotechnology

Enhancement of encapsulation efficiency of nanoemulsion-containing aripiprazole for the treatment of schizophrenia using mixture experimental design

Hamid Reza Fard Masoumi et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2015)

Article Chemistry, Multidisciplinary

Biocompatible Polymeric Nanoparticles as Promising Candidates for Drug Delivery

Sylwia Lukasiewicz et al.

LANGMUIR (2015)

Review Pharmacology & Pharmacy

Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR Review 10

Wakako Fujita et al.

BRITISH JOURNAL OF PHARMACOLOGY (2014)

Article Chemistry, Multidisciplinary

In Vitro Interaction of Polyelectrolyte Nanocapsules with Model Cells

Sylwia Lukasiewicz et al.

LANGMUIR (2014)

Article Chemistry, Applied

A comparative study of chitosan shielding effect on nano-carriers hydrophilicity and biodistribution

Rania A. H. Ishak et al.

CARBOHYDRATE POLYMERS (2013)

Article Clinical Neurology

Nanopsychiatry-The potential role of nanotechnologies in the future of psychiatry: A systematic review

G. Fond et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2013)

Article Medicine, Research & Experimental

Formation of Stable Nanocarriers by in Situ Ion Pairing during Block-Copolymer-Directed Rapid Precipitation

Nathalie M. Pinkerton et al.

MOLECULAR PHARMACEUTICS (2013)

Review Immunology

Expression of recombinant antibodies

Andre Frenzel et al.

FRONTIERS IN IMMUNOLOGY (2013)

Review Neurosciences

The hCMEC/D3 cell line as a model of the human blood brain barrier

Babette Weksler et al.

FLUIDS AND BARRIERS OF THE CNS (2013)

Article Pharmacology & Pharmacy

Anti-Aβ-MAb and dually decorated nanoliposomes: Effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells

Eleni Markoutsa et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2012)

Article Pharmacology & Pharmacy

Nano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced Clearance

Rajendra S. Kadam et al.

DRUG METABOLISM AND DISPOSITION (2012)

Article Pharmacology & Pharmacy

Update on the Adverse Effects of Clozapine: Focus on Myocarditis

Domenico De Berardis et al.

CURRENT DRUG SAFETY (2012)

Review Chemistry, Multidisciplinary

Nanoparticles in Biological Systems

Wendelin J. Stark

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Review Biochemistry & Molecular Biology

Exploring a role for heteromerization in GPCR signalling specificity

Raphael Rozenfeld et al.

BIOCHEMICAL JOURNAL (2011)

Article Endocrinology & Metabolism

Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System

Maud Kamal et al.

Frontiers in Endocrinology (2011)

Article Neurosciences

Heteromerization of G Protein-Coupled Receptors: Relevance to Neurological Disorders and Neurotherapeutics

Laura Albizu et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2010)

Review Biochemistry & Molecular Biology

Interaction of Nanoparticles with Cells

Volker Mailaender et al.

BIOMACROMOLECULES (2009)

Article Clinical Neurology

Nanotechnology for Delivery of Drugs to the Brain for Epilepsy

Margaret F. Bennewitz et al.

NEUROTHERAPEUTICS (2009)

Article Clinical Neurology

The role of D1-D2 receptor hetero-dimerization in the mechanism of action of clozapine

Agata Faron-Gorecka et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2008)

Article Chemistry, Multidisciplinary

Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers

Pascale R. Leroueil et al.

NANO LETTERS (2008)

Article Multidisciplinary Sciences

Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics

Bernard Masri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Pharmacology & Pharmacy

Endocytosis at the blood-brain barrier: From basic understanding to drug delivery strategies

Mathew W. Smith et al.

JOURNAL OF DRUG TARGETING (2006)

Review Multidisciplinary Sciences

Toxic potential of materials at the nanolevel

A Nel et al.

SCIENCE (2006)

Article Pharmacology & Pharmacy

A practical note on the use of cytotoxicity assays

J Weyermann et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2005)