期刊
POLYMERS
卷 13, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/polym13091367
关键词
SARS-CoV-2; antiviral activity; copper film
资金
- Fundamental Research Program of the Korea Institute of Materials Science (KIMS) [PNK7400, PNK7430]
- National Research Foundation of Korea (NRF) [NRF-2020M3A9I4038665, NRF-2020M2D8A1057902]
- National Research Council of Science & Technology (NST), Republic of Korea [PNK7430, PNK7400] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2020M3A9I4038665] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
By depositing a 20 nm copper thin film on a spunbond PP filter surrounding a KF94 face mask, additional protection and decreased risk of secondary transmission were achieved. The copper-coated mask exhibited high filtration efficiencies and demonstrated significant antiviral effects against SARS-CoV-2. This suggests that copper-coated PP filters could be important materials in personal protective equipment and air-conditioning systems.
Face masks will be used to prevent pandemic recurrence and outbreaks of mutant SARS-CoV-2 strains until mass immunity is confirmed. The polypropylene (PP) filter is a representative disposable mask material that traps virus-containing bioaerosols, preventing secondary transmission. In this study, a copper thin film (20 nm) was deposited via vacuum coating on a spunbond PP filter surrounding a KF94 face mask to provide additional protection and lower the risk of secondary transmission. Film adhesion was improved using oxygen ion beam pretreatment, resulting in cuprous oxide formation on the PP fiber without structural deformation. The copper-coated mask exhibited filtration efficiencies of 95.1 +/- 1.32% and 91.6 +/- 0.83% for NaCl and paraffin oil particles, respectively. SARS-CoV-2 inactivation was evaluated by transferring virus-containing media onto the copper-coated PP filters and subsequently adding Vero cells. Infection was verified using real-time polymerase chain reaction and immunochemical staining. Vero cells added after contact with the copper-coated mask did not express the RNA-dependent RNA polymerase and envelope genes of SARS-CoV-2. The SARS-CoV-2 nucleocapsid immunofluorescence results indicated a reduction in the amount of virus of more than 75%. Therefore, copper-coated antiviral PP filters could be key materials in personal protective equipment, as well as in air-conditioning systems.
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