期刊
出版社
MDPI
DOI: 10.3390/ijerph18094852
关键词
dopamine; epinephrine; GABA; ghrelin; melatonin; serotonin
资金
- Research Center at King Fahd Medical City, Riyadh
Research on biomarkers in male breast cancer patients is limited, but this study found significantly higher levels of serum melatonin and epinephrine in male breast cancer patients, while ghrelin, dopamine, GABA, and serotonin levels were lower. The serum levels of most biomarkers in male breast cancer patients were similar to those in female breast cancer patients, except for serum melatonin levels.
The global incidence of breast cancer among men is steadily growing. Despite this, compared to female breast cancer patients, there are very few studies on biomarkers in male breast cancer patients. A cross-sectional case control study was carried out to determine the serum levels of melatonin, ghrelin, dopamine, serotonin, epinephrine, and GABA in male breast cancer. All the recruited patients were obese, old, and had recently been diagnosed with the disease. They had not received any treatment for the cancer until the time of the study. Melatonin and epinephrine serum levels were significantly higher in breast cancer patients compared to their age-matched controls, whereas ghrelin, dopamine, GABA, and serotonin serum levels were lower in patients compared to the control group. The serum levels of most of the studied biomarkers in male breast cancer patients were similar to those observed in female breast cancer patients, except for serum melatonin levels.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据