4.7 Article

Generation of a chemical genetic model for JAK3

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Loss of Mef2D function enhances TLR induced IL-10 production in macrophages

Michael J. Pattison et al.

BIOSCIENCE REPORTS (2020)

Review Chemistry, Medicinal

Current Status in the Discovery of Covalent Janus Kinase 3 (JAK3) Inhibitors

Jun Dai et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2019)

Review Immunology

JAK inhibitors for the treatment of autoimmune and inflammatory diseases

Yvan Jamilloux et al.

AUTOIMMUNITY REVIEWS (2019)

Article Pharmacology & Pharmacy

Upadacitinib: First Approval

Sean Duggan et al.

News Item Biotechnology & Applied Microbiology

FDA approves Eli Lilly's baricitinib

Asher Mullard

NATURE REVIEWS DRUG DISCOVERY (2018)

Review Biotechnology & Applied Microbiology

JAK inhibition as a therapeutic strategy for immune and inflammatory diseases

Daniella M. Schwartz et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

Article Chemistry, Medicinal

Recent advances in JAK3 inhibition: Isoform selectivity by covalent cysteine targeting

Michael Forster et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Review Immunology

Mechanisms and consequences of Jak-STAT signaling in the immune system

Alejandro V. Villarino et al.

NATURE IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling

Geoffrey A. Smith et al.

NATURE CHEMICAL BIOLOGY (2016)

Editorial Material Biochemistry & Molecular Biology

Commentary: IL-4 and IL-13 receptors and signaling

Sarah M. McCormick et al.

CYTOKINE (2015)

Article Chemistry, Medicinal

Development of Selective Covalent Janus Kinase 3 Inhibitors

Li Tan et al.

JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

Eric R. Goedken et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Chemistry, Medicinal

Selective inhibitors of the Janus kinase Jak3-Are they effective?

Gebhard Thoma et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Review Biochemistry & Molecular Biology

Developing Irreversible Inhibitors of the Protein Kinase Cysteinome

Qingsong Liu et al.

CHEMISTRY & BIOLOGY (2013)

News Item Biotechnology & Applied Microbiology

Pfizer's first-in-class JAK inhibitor pricey for rheumatoid arthritis market

Ken Garber

NATURE BIOTECHNOLOGY (2013)

Review Immunology

Inborn Errors of Human JAKs and STATs

Jean-Laurent Casanova et al.

IMMUNITY (2012)

Review Immunology

The JAK-STAT Pathway at Twenty

George R. Stark et al.

IMMUNITY (2012)

Editorial Material Biochemistry & Molecular Biology

JAK3 Specific Kinase Inhibitors: When Specificity Is Not Enough

Luk Cox et al.

CHEMISTRY & BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Jak1 Has a Dominant Role over Jak3 in Signal Transduction through γc-Containing Cytokine Receptors

Claude Haan et al.

CHEMISTRY & BIOLOGY (2011)

Article Chemistry, Medicinal

Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family

Gebhard Thoma et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

The selectivity of protein kinase inhibitors: a further update

Jenny Bain et al.

BIOCHEMICAL JOURNAL (2007)

Review Oncology

Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders

Ross L. Levine et al.

NATURE REVIEWS CANCER (2007)

Article Multidisciplinary Sciences

A chemical switch for inhibitor-sensitive alleles of any protein kinase

AC Bishop et al.

NATURE (2000)