相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。miR-92b-3p-TSC1 axis is critical for mTOR signaling-mediated vascular smooth muscle cell proliferation induced by hypoxia
Jihui Lee et al.
CELL DEATH AND DIFFERENTIATION (2019)
microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1
Gang Liu et al.
ONCOTARGET (2018)
Circulating Exosomal miR-27a and miR-130a Act as Novel Diagnostic and Prognostic Biomarkers of Colorectal Cancer
Xiangxiang Liu et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2018)
Immune TOR-opathies, a Novel Disease Entity in Clinical Immunology
Sophie Jung et al.
FRONTIERS IN IMMUNOLOGY (2018)
Exosome-Derived miR-130a Activates Angiogenesis in Gastric Cancer by Targeting C-MYB in Vascular Endothelial Cells
Haiou Yang et al.
MOLECULAR THERAPY (2018)
The MYB/miR-130a/NDRG2 axis modulates tumor proliferation and metastatic potential in salivary adenoid cystic carcinoma
Yu Wang et al.
CELL DEATH & DISEASE (2018)
MiR-126-3p promotes the cell proliferation and inhibits the cell apoptosis by targeting TSC1 in the porcine granulosa cells
Xiaolong Yuan et al.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2018)
Differential Expression of MicroRNA-19b Promotes Proliferation of Cancer Stem Cells by Regulating the TSC1/mTOR Signaling Pathway in Multiple Myeloma
Ni Wang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
TSC1/2 mutations define a molecular subset of HCC with aggressive behaviour and treatment implication
Daniel W. H. Ho et al.
GUT (2017)
The differential regulation of microRNAs is associated with oral cancer
Shih-Chang Tsai et al.
ONCOLOGY REPORTS (2017)
Downregulation of MicroRNA-193b-3p Promotes Autophagy and Cell Survival by Targeting TSC1/mTOR Signaling in NSC-34 Cells
ChunYu Li et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)
Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice
Hong-Mei Zhang et al.
SCIENTIFIC REPORTS (2017)
miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma
Yuqiong Wang et al.
CELL DEATH AND DIFFERENTIATION (2017)
A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer
Qian Zhao et al.
ONCOTARGET (2016)
miR-194 regulated AGK and inhibited cell proliferation of oral squamous cell carcinoma by reducing PI3K-Akt-FoxO3a signaling
Hongyu Chi
BIOMEDICINE & PHARMACOTHERAPY (2015)
TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
Antje Thien et al.
DEVELOPMENTAL CELL (2015)
miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3
Hong Jiang et al.
ONCOLOGY REPORTS (2015)
MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma
Juan Du et al.
ONCOTARGET (2015)
AKT3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf & TSC1/TSC2
Hui-Ping Lin et al.
ONCOTARGET (2015)
Targeting of RUNX3 by miR-130a and miR-495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells
Sun Hee Lee et al.
ONCOTARGET (2015)
Genomic amplification upregulates estrogen-related receptor alpha and its depletion inhibits oral squamous cell carcinoma tumors in vivo
Ankana Tiwari et al.
SCIENTIFIC REPORTS (2015)
Genetic Variations in STK11, PRKAA1, and TSC1 Associated with Prognosis for Patients with Colorectal Cancer
Soo Jung Lee et al.
ANNALS OF SURGICAL ONCOLOGY (2014)
Prognostic implication of TSC1 and mTOR expression in gastric carcinoma
Sun-Ju Byeon et al.
JOURNAL OF SURGICAL ONCOLOGY (2014)
Reciprocal regulation of MicroRNA-99a and insulin-like growth factor 1 receptor signaling in oral squamous cell carcinoma cells
Yi-Chen Yen et al.
MOLECULAR CANCER (2014)
Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin
Shalmali Avinash Pradhan et al.
NUCLEIC ACIDS RESEARCH (2014)
MicroRNAs in cancer: biomarkers, functions and therapy
Josie Hayes et al.
TRENDS IN MOLECULAR MEDICINE (2014)
Oncogenic MicroRNA-155 Down-regulates Tumor Suppressor CDC73 and Promotes Oral Squamous Cell Carcinoma Cell Proliferation IMPLICATIONS FOR CANCER THERAPEUTICS
Mohammad Iqbal Rather et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
TSC1 involvement in bladder cancer: diverse effects andtherapeutic implications
Yanan Guo et al.
JOURNAL OF PATHOLOGY (2013)
Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
Michalis Papadakis et al.
NATURE MEDICINE (2013)
TSC1 Controls Distribution of Actin Fibers through Its Effect on Function of Rho Family of Small GTPases and Regulates Cell Migration and Polarity
Maki Ohsawa et al.
PLOS ONE (2013)
Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer
Yutaka Hashimoto et al.
PLOS ONE (2013)
Differential expression of miRNAs in esophageal cancer tissue
Shang-Guo Liu et al.
ONCOLOGY LETTERS (2013)
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
Christian C. Dibble et al.
MOLECULAR CELL (2012)
Expression of miRNA-130a in Nonsmall Cell Lung Cancer
Xiao-Chun Wang et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2010)
Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice
Raleigh D. Kladney et al.
CANCER RESEARCH (2010)
TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity
M-C Liang et al.
ONCOGENE (2010)
Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma
Sanjukta Chakraborty et al.
BMC CANCER (2008)
miR-Q: a novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample
Soroush Sharbati-Tehrani et al.
BMC MOLECULAR BIOLOGY (2008)
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway
Dung-Fang Lee et al.
CELL (2007)
Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner
A Astrinidis et al.
HUMAN MOLECULAR GENETICS (2006)
Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer:: The role of promoter methylation of TSC genes
WG Jiang et al.
EUROPEAN JOURNAL OF CANCER (2005)
Cell cycle-regulated phosphorylation of hamartin, the product of the tuberous sclerosis complex 1 gene, by cyclin-dependent kinase 1 cyclin B
A Astrinidis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
AR Tee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice
T Kobayashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination
G Benvenuto et al.
ONCOGENE (2000)
The TSC1 gene product, hamartin, negatively regulates cell proliferation
A Miloloza et al.
HUMAN MOLECULAR GENETICS (2000)
The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
RF Lamb et al.
NATURE CELL BIOLOGY (2000)
分享论文
