相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Shortened TDP43 isoforms upregulated by neurona hyperactivity drive TDP43 pathology in ALS
Kaitlin Weskamp et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
TDP-43 Is Elevated in Plasma Neuronal-Derived Exosomes of Patients With Alzheimer's Disease
Nan Zhang et al.
FRONTIERS IN AGING NEUROSCIENCE (2020)
Evidence of A Negative Feedback Network Between TDP-43 and miRNAs Dependent on TDP-43 Nuclear Localization
Zachary C. E. Hawley et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation
Akihiro Sugai et al.
NEUROBIOLOGY OF DISEASE (2019)
DBTSS/DBKERO for integrated analysis of transcriptional regulation
Ayako Suzuki et al.
NUCLEIC ACIDS RESEARCH (2018)
TDP-43 as a potential biomarker for amyotrophic lateral sclerosis: a systematic review and meta-analysis
Vivek Majumder et al.
BMC NEUROLOGY (2018)
Pathomechanisms of TDP-43 in neurodegeneration
Ju Gao et al.
JOURNAL OF NEUROCHEMISTRY (2018)
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
Matthew A. White et al.
NATURE NEUROSCIENCE (2018)
Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data
Akihiro Sugai et al.
FRONTIERS IN NEUROSCIENCE (2018)
The eukaryotic promoter database in its 30th year: focus on non-vertebrate organisms
Rene Dreos et al.
NUCLEIC ACIDS RESEARCH (2017)
Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies
Lin Guo et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins
Antonia Ratti et al.
JOURNAL OF NEUROCHEMISTRY (2016)
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins
S. Prpar Mihevc et al.
SCIENTIFIC REPORTS (2016)
HEK293 in cell biology and cancer research: phenotype, karyotype, tumorigenicity, and stress-induced genome-phenotype evolution
A. A. Stepanenko et al.
GENE (2015)
AN AGE-RELATED REDUCTION OF BRAIN TBPH/TDP-43 LEVELS PRECEDES THE ONSET OF LOCOMOTION DEFECTS IN A DROSOPHILA ALS MODEL
L. Cragnaz et al.
NEUROSCIENCE (2015)
TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways
Laura De Conti et al.
NUCLEIC ACIDS RESEARCH (2015)
Incidence and extent of TDP-43 accumulation in aging human brain
Akiko Uchino et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain
Mauricio Budini et al.
HUMAN MOLECULAR GENETICS (2015)
DBTSS as an integrative platform for transcriptome, epigenome and genome sequence variation data
Ayako Suzuki et al.
NUCLEIC ACIDS RESEARCH (2015)
Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation
Marc Suarez-Calvet et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)
Predominance of spliceosomal complex formation over polyadenylation site selection in TDP-43 autoregulation
Sara Bembich et al.
NUCLEIC ACIDS RESEARCH (2014)
TDP-43-mediated neurodegeneration: towards a loss-of-function hypothesis?
Lies Vanden Broeck et al.
TRENDS IN MOLECULAR MEDICINE (2014)
Loss of TDP-43 causes age-dependent progressive motor neuron degeneration
Yohei Iguchi et al.
BRAIN (2013)
TDP-43 plasma levels are higher in amyotrophic lateral sclerosis
Esther Verstraete et al.
AMYOTROPHIC LATERAL SCLEROSIS (2012)
GPMiner: an integrated system for mining combinatorial cis-regulatory elements in mammalian gene group
Tzong-Yi Lee et al.
BMC GENOMICS (2012)
Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43
Azusa Uchida et al.
BRAIN (2012)
Rodent models of TDP-43: Recent advances
William Tsao et al.
BRAIN RESEARCH (2012)
Before It Gets Started: Regulating Translation at the 5′ UTR
Patricia R. Araujo et al.
COMPARATIVE AND FUNCTIONAL GENOMICS (2012)
Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection
S. Erendira Avendano-Vazquez et al.
GENES & DEVELOPMENT (2012)
Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime
Cao Huang et al.
International Journal of Biological Sciences (2012)
Cellular Model of TAR DNA-binding Protein 43 (TDP-43) Aggregation Based on Its C-terminal Gln/Asn-rich Region
Mauricio Budini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Does a loss of TDP-43 function cause neurodegeneration?
Zuo-Shang Xu
MOLECULAR NEURODEGENERATION (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Elevated CSF TDP-43 levels in amyotrophic lateral sclerosis: Specificity, sensitivity, and a possible prognostic value
Yu-Ichi Noto et al.
AMYOTROPHIC LATERAL SCLEROSIS (2011)
Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway
Jean-Luc C. Mougeot et al.
BMC MEDICAL GENOMICS (2011)
TDP-43 regulates its mRNA levels through a negative feedback loop
Youhna M. Ayala et al.
EMBO JOURNAL (2011)
TDP-43: new aspects of autoregulation mechanisms in RNA binding proteins and their connection with human disease
Emanuele Buratti et al.
FEBS JOURNAL (2011)
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
Lionel M. Igaz et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways
Vivek Swarup et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
TDP-43 pathology in primary progressive aphasia and frontotemporal dementia with pathologic Alzheimer disease
Eileen H. Bigio et al.
ACTA NEUROPATHOLOGICA (2010)
Neurotoxic effects of TDP-43 overexpression in C-elegans
Peter E. A. Ash et al.
HUMAN MOLECULAR GENETICS (2010)
TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development
Chantelle F. Sephton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
Ya-Fei Xu et al.
JOURNAL OF NEUROSCIENCE (2010)
Progressive motor weakness in transgenic mice expressing human TDP-43
Nancy R. Stallings et al.
NEUROBIOLOGY OF DISEASE (2010)
A Drosophila model for TDP-43 proteinopathy
Yan Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
Xiu Shan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
Hans Wils et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genome-wide functional analysis of human 5 ' untranslated region introns
Can Cenik et al.
GENOME BIOLOGY (2010)
Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis
Takashi Kasai et al.
ACTA NEUROPATHOLOGICA (2009)
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior
Fabian Feiguin et al.
FEBS LETTERS (2009)
Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE
Eivind Valen et al.
GENOME RESEARCH (2009)
Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis
Natasha Luquin et al.
NEUROMUSCULAR DISORDERS (2009)
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
Iga Wegorzewska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration
Penelope Foulds et al.
ACTA NEUROPATHOLOGICA (2008)
Atypical frontotemporal lobar degeneration with ubiquitin-positive, TDP-43-negative neuronal inclusions
Ian R. A. Mackenzie et al.
BRAIN (2008)
Concomitant TAR-DNA-binding in Alzheimer disease and protein 43 pathology is present corticobasal degeneration but not in other tauopathies
Kunihiro Uryu et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
TAR-DNA binding protein 43 in Pick disease
Stefanie H. Freeman et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
A code for transcription initiation in mammalian genomes
Martin C. Frith et al.
GENOME RESEARCH (2008)
Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies
Shinji Higashi et al.
BRAIN RESEARCH (2007)
Hippocampal sclerosis dementia: a reappraisal
Alphonse Probst et al.
ACTA NEUROPATHOLOGICA (2007)
TDP-43 is deposited in the Guam parkinsonism-dementia complex brains
Masato Hasegawa et al.
BRAIN (2007)
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
Catalina Amador-Ortiz et al.
ANNALS OF NEUROLOGY (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Genome-wide analysis of mammalian promoter architecture and evolution
Piero Carninci et al.
NATURE GENETICS (2006)
Mice and men:: Their promoter properties
Vladimir B. Bajic et al.
PLOS GENETICS (2006)
Genome-wide analysis reveals strong correlation between CpG islands with nearby transcription start sites of genes and their tissue specificity
R Yamashita et al.
GENE (2005)
MUSCLE: multiple sequence alignment with high accuracy and high throughput
RC Edgar
NUCLEIC ACIDS RESEARCH (2004)
Clustering of DNA sequences in human promoters
PC FitzGerald et al.
GENOME RESEARCH (2004)
Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of Exon 9: A functional link with disease penetrance
E Buratti et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Stimulatory effect of splicing factors on transcriptional elongation
YW Fong et al.
NATURE (2001)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
E Buratti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
H Le Hir et al.
EMBO JOURNAL (2001)
Introns and their positions affect the translational activity of mRNA in plant cells
V Bourdon et al.
EMBO REPORTS (2001)
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
E Buratti et al.
EMBO JOURNAL (2001)
Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element
F Pagani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)