4.7 Article

A novel proteomics approach to epigenetic profiling of circulating nucleosomes

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Mass spectrometry-based characterization of histones in clinical samples: applications, progresses, and challenges

Roberta Noberini et al.

Summary: In the past 15 years, research has shown the potential of investigating histone post-translational modifications and variants in clinical samples for discovering biomarkers and therapeutic targets in cancer biology. Mass spectrometry has emerged as a powerful tool for unbiased, comprehensive, and quantitative investigation of histones in clinical samples, with recent advancements in technology expanding its application possibilities. The 'bottom-up' strategy of analyzing short proteolytic peptides has shown success in clinical sample analysis, offering a promising approach for histone PTM profiling.

FEBS JOURNAL (2022)

Article Oncology

Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma

Shejuan An et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)

Article Cell Biology

Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin

Qi Wang et al.

JOURNAL OF MOLECULAR CELL BIOLOGY (2020)

Review Genetics & Heredity

Clinical epigenetics: seizing opportunities for translation

Maria Berdasco et al.

NATURE REVIEWS GENETICS (2019)

Review Gastroenterology & Hepatology

Genetic and epigenetic alterations of colorectal cancer

Sung Noh Hong

INTESTINAL RESEARCH (2018)

Article Oncology

Circulating nucleosomes as new blood-based biomarkers for detection of colorectal cancer

Jean-Francois Rahier et al.

CLINICAL EPIGENETICS (2017)

Article Multidisciplinary Sciences

A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients

J. L. Garcia-Gimenez et al.

SCIENTIFIC REPORTS (2017)

Editorial Material Biochemical Research Methods

Reshaping the Chromatin and Epigenetic Landscapes with Quantitative Mass Spectrometry

Michael P. Washburn et al.

MOLECULAR & CELLULAR PROTEOMICS (2016)

Review Oncology

Biomarkers of genome instability and cancer epigenetics

Adriana H. O. Reis et al.

TUMOR BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Histone Methylation Marks on Circulating Nucleosomes as Novel Blood-Based Biomarker in Colorectal Cancer

Ugur Gezer et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Oncology

Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer

Monika Bauden et al.

CLINICAL EPIGENETICS (2015)

Review Cell Biology

Histone core modifications regulating nucleosome structure and dynamics

Peter Tessarz et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Biochemical Research Methods

Histone H3 lysine 27 acetylation is altered in colon cancer

Jakub Karczmarski et al.

CLINICAL PROTEOMICS (2014)

Review Biochemistry & Molecular Biology

The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients

Yahya I. Elshimali et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Oncology

Epigenetics and Colorectal Cancer Pathogenesis

Kankana Bardhan et al.

Cancers (2013)

Article Biochemistry & Molecular Biology

Asymmetrically Modified Nucleosomes

Philipp Voigt et al.

Review Genetics & Heredity

Histone methylation: a dynamic mark in health, disease and inheritance

Eric L. Greer et al.

NATURE REVIEWS GENETICS (2012)

Review Cell Biology

Regulation of chromatin by histone modifications

Andrew J. Bannister et al.

CELL RESEARCH (2011)

Review Biochemistry & Molecular Biology

Histone onco-modifications

J. Fullgrabe et al.

ONCOGENE (2011)

Review Oncology

Cell-free nucleic acids as biomarkers in cancer patients

Heidi Schwarzenbach et al.

NATURE REVIEWS CANCER (2011)

Review Biotechnology & Applied Microbiology

Epigenetic modifications and human disease

Anna Portela et al.

NATURE BIOTECHNOLOGY (2010)

Article Pathology

Global Levels of Histone Modifications Predict Prognosis in Different Cancers

David B. Seligson et al.

AMERICAN JOURNAL OF PATHOLOGY (2009)

Article Biochemistry & Molecular Biology

Clinical relevance of circulating nucleosomes in cancer

Stefan Holdenrieder et al.

CIRCULATING NUCLEIC ACIDS IN PLASMA AND SERUM V (2008)