期刊
NUTRIENTS
卷 13, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/nu13031016
关键词
probiotic; Limosilactobacillus fermentum CECT5716; immunomodulation; dysbiosis; mechanisms of action; gastrointestinal diseases; microbiota
资金
- Junta de Andalucia [CTS 164]
- Instituto de Salud Carlos III [PI19/01058]
- European Union
Probiotic microorganisms exert their health-associated activities through various mechanisms, with Limosilactobacillus fermentum CECT5716 standing out as a promising probiotic with anti-inflammatory and immunomodulatory properties. Studies have shown its potential beneficial effects on host health and future therapeutic approaches are being explored.
Probiotics microorganisms exert their health-associated activities through some of the following general actions: competitive exclusion, enhancement of intestinal barrier function, production of bacteriocins, improvement of altered microbiota, and modulation of the immune response. Among them, Limosilactobacillus fermentum CECT5716 has become one of the most promising probiotics and it has been described to possess potential beneficial effects on inflammatory processes and immunological alterations. Different studies, preclinical and clinical trials, have evidenced its anti-inflammatory and immunomodulatory properties and elucidated the precise mechanisms of action involved in its beneficial effects. Therefore, the aim of this review is to provide an updated overview of the effect on host health, mechanisms, and future therapeutic approaches.
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