期刊
NUTRIENTS
卷 13, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/nu13041127
关键词
Palm Fruit Bioactive complex; PFBc; inflammaging; mild cognitive impairment; polyphenols; antioxidant; cognitive function; anti-inflammatory
资金
- Phenolaies NA, LLC
Cognitive function is crucial for healthy aging, with inflammaging being a primary risk factor for cognitive decline. A diet high in antioxidants and polyphenols, such as the Mediterranean Diet, can lower the risk of age-related cognitive decline. PFBc, a phenolic derived from palm oil, is reported to offset inflammation and improve cognitive function through its high antioxidant and polyphenol content.
Cognitive function is a key aspect of healthy aging. Inflammation associated with normal aging, also called inflammaging is a primary risk factor for cognitive decline. A diet high in fruits and vegetable and lower in calories, particularly a Mediterranean Diet, may lower the risk of age-related cognitive decline due in part to the associated high intake of antioxidants and polyphenols. A phenolic, Palm Fruit Bioactive complex (PFBc) derived from the extraction process of palm oil from oil palm fruit (Elaeis guineensis), is reported to offset inflammation due to its high antioxidant, especially vitamin E, and polyphenol content. The benefit is thought to be achieved via the influence of antioxidants on gene expression. It is the purpose of this comprehensive review to discuss the etiology, including gene expression, of mild cognitive impairment (MCI) specific to dietary intake of antioxidants and polyphenols and to focus on the potential impact of nutritional interventions specifically PFBc has on MCI. Several in vitro, in vivo and animal studies support multiple benefits of PFBc especially for improving cognitive function via anti-inflammatory and antioxidant mechanisms. While more human studies are needed, those completed thus far support the benefit of consuming PFBc to enhance cognitive function via its anti-inflammatory antioxidant functions.
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