Hard Dental Tissues Regeneration-Approaches and Challenges

With the development of the modern concept of tissue engineering approach and the discovery of the potential of stem cells in dentistry, the regeneration of hard dental tissues has become a reality and a priority of modern dentistry. The present review reports the recent advances on stem-cell based regeneration strategies for hard dental tissues and analyze the feasibility of stem cells and of growth factors in scaffolds-based or scaffold-free approaches in inducing the regeneration of either the whole tooth or only of its component structures.

Automated summary

With the development of modern tissue engineering concepts and the discovery of stem cell potential in dentistry, the regeneration of hard dental tissues has become a priority. Advances in stem cell-based regeneration strategies and the feasibility of using growth factors in scaffold-based or scaffold-free approaches have shown promise in inducing tooth regeneration.