期刊
INTERNATIONAL JOURNAL OF SURGERY
卷 89, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.ijsu.2021.105948
关键词
LASSO; Logistic regression; Risk factors; Urologic surgical procedures; Venous thrombosis
类别
资金
- National Natural Science Foundation of China [81874094, 81974397]
- Hunan Provincial Natural Science Foundation of China [2019JJ40484]
- Science and Technology Plan Projects of Changsha city [kq1801114]
- Project from Health and Family Planning Commission of Hunan Province [C20180105]
This study aimed to analyze the incidence and risk factors of lower extremity venous thrombosis after urologic surgery. Age, history of DVT, lymph node dissection were identified as factors associated with DVT occurrence. Using the LASSO logistic regression model provided reliable data on risk factors for DVT.
Background: Deep vein thrombosis (DVT) is among the most frequent complications of surgery. This study aimed to analyse the incidence and risk factors of lower extremity venous thrombosis after urologic surgery. Materials and methods: This prospective two-centre study was conducted from August 2019 to January 2020. Patients who underwent urological procedures were enrolled. The primary endpoint was the detection of asymptomatic or symptomatic DVT of the lower extremity within 7 days after surgery. Univariate and least absolute shrinkage and selection operator (LASSO) logistic regression analyses were performed. Results: Fifty-six of 1011 patients developed DVT. In the univariate analysis, Barthel Index <= 40, D-dimer level >0.5 mg/L and age >60 years (p < 0.001) were identified as the most significant risk factors. The LASSO logistic regression model identified nine factors: age, history of DVT, lymph node dissection, perioperative steroid use, Caprini score, Barthel Index, D-dimer level, cystectomy, and prostatectomy. Conclusion: Our study used the LASSO logistic regression model to provide reliable data on the risk factors for DVT after comprehensive urologic surgery. The incidence of DVT in this group was 5.54%. This might facilitate individualised anticoagulant management in patients undergoing urological procedures.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据