4.7 Review

Potential Anti-Coronavirus Agents and the Pharmacologic Mechanisms

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Immunology

Review Article Genotype and phenotype of COVID-19: Their roles in pathogenesis

Leila Mousavizadeh et al.

Summary: COVID-19 is a novel coronavirus belonging to the Betacoronavirus genus, with similarities and differences in genomic structure compared to other human Betacoronaviruses. It contains at least six open reading frames and important structural proteins are encoded near the one-third of the genome.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2021)

Article Multidisciplinary Sciences

The coding capacity of SARS-CoV-2

Yaara Finkel et al.

Summary: A high-resolution map of coding regions in the SARS-CoV-2 genome enables the identification of 23 unannotated open reading frames and quantification of the expression of canonical viral open reading frames.

NATURE (2021)

Article Medicine, General & Internal

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia

Carlos Salama et al.

Summary: Among hospitalized patients with Covid-19 pneumonia not on mechanical ventilation, tocilizumab reduced the risk of progression to mechanical ventilation or death, but did not improve overall survival. There were no new safety concerns identified.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Biochemistry & Molecular Biology

Structure analysis of the receptor binding of 2019-nCoV

Yun Chen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Editorial Material Gastroenterology & Hepatology

Evidence for Gastrointestinal Infection of SARS-CoV-2

Fei Xiao et al.

GASTROENTEROLOGY (2020)

Article Medicine, General & Internal

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

Dawei Wang et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Review Immunology

The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak

Hussin A. Rothan et al.

JOURNAL OF AUTOIMMUNITY (2020)

Review Virology

Emerging coronaviruses: Genome structure, replication, and pathogenesis

Yu Chen et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Article Medicine, General & Internal

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang et al.

LANCET (2020)

Editorial Material Biotechnology & Applied Microbiology

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

Guangdi Li et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Article Medicine, General & Internal

Clinical Characteristics of Coronavirus Disease 2019 in China

W. Guan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Letter Medicine, General & Internal

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

Lirong Zou et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

A Novel Coronavirus from Patients with Pneumonia in China, 2019

Na Zhu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Editorial Material Cardiac & Cardiovascular Systems

COVID-19 in the heart and the lungs: could we Notch the inflammatory storm?

Paola Rizzo et al.

BASIC RESEARCH IN CARDIOLOGY (2020)

Article Biochemistry & Molecular Biology

Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase

Quan Wang et al.

Article Critical Care Medicine

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

Zhe Xu et al.

LANCET RESPIRATORY MEDICINE (2020)

Article Infectious Diseases

Cytokine storm and immunomodulatory therapy in COVID-19: Role of chloroquine and anti-IL-6 monoclonal antibodies

Ming Zhao

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Infectious Diseases

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Philippe Gautret et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Medicine, General & Internal

COVID-19 may transmit through aerosol

Juan Wang et al.

IRISH JOURNAL OF MEDICAL SCIENCE (2020)

Article Allergy

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Tobias Herold et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Article Multidisciplinary Sciences

Effective treatment of severe COVID-19 patients with tocilizumab

Xiaoling Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Letter Virology

Elevated interleukin-6 and severe COVID-19: A meta-analysis

Muhammad Aziz et al.

JOURNAL OF MEDICAL VIROLOGY (2020)

Review Virology

Virology, Epidemiology, Pathogenesis, and Control of COVID-19

Yuefei Jin et al.

VIRUSES-BASEL (2020)

Review Public, Environmental & Occupational Health

Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review

Anwar M. Hashem et al.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2020)

Letter Immunology

Chloroquine paradox may cause more damage than help fight COVID-19

Anuj Sharma

MICROBES AND INFECTION (2020)

Editorial Material Medicine, General & Internal

Covid-19-The Search for Effective Therapy

Lindsey R. Baden et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19

B. Cao et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

Compassionate Use of Remdesivir for Patients with Severe Covid-19

J. Grein et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Review Pharmacology & Pharmacy

Molecular immune pathogenesis and diagnosis of COVID-19

Xiaowei Li et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2020)

Article Medicine, General & Internal

Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 A Randomized Trial

Caleb P. Skipper et al.

ANNALS OF INTERNAL MEDICINE (2020)

Review Infectious Diseases

The pathogenesis and treatment of the 'Cytokine Storm' in COVID-19

Qing Ye et al.

JOURNAL OF INFECTION (2020)

Article Biochemical Research Methods

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase, a Key Drug Target for COVID-19

Minchen Chien et al.

JOURNAL OF PROTEOME RESEARCH (2020)

Review Biochemistry & Molecular Biology

Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting

Fran Robson et al.

MOLECULAR CELL (2020)

Article Multidisciplinary Sciences

Sofosbuvir as a potential alternative to treat the SARS-CoV-2 epidemic

Rodrigo Jacome et al.

SCIENTIFIC REPORTS (2020)

Article Infectious Diseases

The impact of sofosbuvir/daclatasvir or ribavirin in patients with severe COVID-19

Gholamali Eslami et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)

Article Multidisciplinary Sciences

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity

Suzanne J. F. Kaptein et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Neuropilin-1 is a host factor for SARS-CoV-2 infection

James L. Daly et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

Michael Schoof et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

Genomics functional analysis and drug screening of SARS-CoV-2

Long Chen et al.

GENES & DISEASES (2020)

Article Biochemistry & Molecular Biology

Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV-2) through a drug-target interaction deep learning model

Bo Ram Beck et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2020)

Article Microbiology

MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

Vineet D. Menachery et al.

Review Biotechnology & Applied Microbiology

Coronaviruses - drug discovery and therapeutic options

Alimuddin Zumla et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Review Microbiology

SARS and MERS: recent insights into emerging coronaviruses

Emmie de Wit et al.

NATURE REVIEWS MICROBIOLOGY (2016)

Article Biochemistry & Molecular Biology

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

Vineet D. Menachery et al.

NATURE MEDICINE (2015)

Review Virology

MERS coronavirus: diagnostics, epidemiology and transmission

Ian M. Mackay et al.

VIROLOGY JOURNAL (2015)

Review Pharmacology & Pharmacy

Accessory proteins of SARS-CoV and other coronaviruses

Ding Xiang Liu et al.

ANTIVIRAL RESEARCH (2014)

Article Multidisciplinary Sciences

Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein

Jean Kaoru Millet et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Virology

The Coronavirus E Protein: Assembly and Beyond

Travis R. Ruch et al.

VIRUSES-BASEL (2012)

Review Ecology

Pacing a small cage: mutation and RNA viruses

Robert Belshaw et al.

TRENDS IN ECOLOGY & EVOLUTION (2008)

Article Virology

Coronavirus nucleocapsid protein is an RNA chaperone

Sonia Zuniga et al.

VIROLOGY (2007)

Article Multidisciplinary Sciences

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

G Simmons et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Biotechnology & Applied Microbiology

Virus-encoded proteinases and proteolytic processing in the Nidovirales

J Ziebuhr et al.

JOURNAL OF GENERAL VIROLOGY (2000)