期刊
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
卷 45, 期 5, 页码 -出版社
ELSEVIER MASSON, CORP OFF
DOI: 10.1016/j.clinre.2021.101712
关键词
miRNA125b; Hepatocellular carcinoma; Progression
资金
- Natural Science Foundation of the Higher Education Institutions of Anhui Province [KJ2017A825]
- Natural Science Foundation of Anhui Province [1808085MH270]
miR-125b, as a significant miRNA, plays a crucial role in predicting and prognosing hepatocellular carcinoma (HCC). It inhibits the development of HCC and is highly accurate in prediction, making it a valuable predictive marker of HCC.
Hepatocellular carcinoma (HCC) is one of the most common tumours worldwide, and identifying markers related to HCC is an important area of research. As a microRNA (miRNA), miRNA125b (miR-125b) plays an important role in the prediction and prognosis of HCC. In the past 10 years, with increasing research on miR-125b and HCC, the molecular mechanism of its relationship with the development of HCC has been elucidated. MiR-125b inhibits the development of HCC and is highly accurate in predicting HCC and is therefore a valuable predictive marker of HCC. This article summarizes the clinical application of miR-125b in HCC and the potential mechanism of its involvement in the progression of HCC. (c) 2021 Elsevier Masson SAS. All rights reserved.
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