Cross-Coupling of Ketone Enolates with Grignard and Zinc Reagents with First-Row Transition Metal Catalysts

The stereoselective transformation of ketones to substituted olefins has become of great importance in organic synthesis. This Review helps to define the scope and limitations of the first-row transition metal-catalyzed cross-couplings between various enolates and aryl, heteroaryl, alkenyl, alkynyl, and alkyl Grignard and zinc reagents.

Automated summary

This review discusses the scope and limitations of stereoselective transformation of ketones to substituted olefins using first-row transition metal-catalyzed cross-couplings with various Grignard and zinc reagents.