相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment
Pan Chen et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2019)
A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition
Mallory R. Smith et al.
NUCLEIC ACIDS RESEARCH (2019)
Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining
John M. Pryor et al.
SCIENCE (2018)
Hiding in Plain Sight: The Bimetallic Magnesium Covalent Bond in Enzyme Active Sites
Lalith Perera et al.
INORGANIC CHEMISTRY (2017)
MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?
Yusaku Nakabeppu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Modulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction
David D. Shock et al.
NATURE CHEMICAL BIOLOGY (2017)
Oxidized nucleotide insertion by pol β confounds ligation during base excision repair
Melike Caglayan et al.
NATURE COMMUNICATIONS (2017)
Time-lapse crystallography snapshots of a double-strand break repair polymerase in action
Joonas A. Jamsen et al.
NATURE COMMUNICATIONS (2017)
A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG
Matthew J. Burak et al.
EMBO JOURNAL (2016)
Kinetic selection vs. free energy of DNA base pairing in control of polymerase fidelity
Keriann Oertell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Capture of a third Mg2+ is essential for catalyzing DNA synthesis
Yang Gao et al.
SCIENCE (2016)
EIGER detector: application in macromolecular crystallography
Arnau Casanas et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2016)
Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography
Rajan Vyas et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda
Matthew J. Burak et al.
NUCLEIC ACIDS RESEARCH (2015)
Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse
Lalith Perera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide
Bret D. Freudenthal et al.
NATURE (2015)
ROS Function in Redox Signaling and Oxidative Stress
Michael Schieber et al.
CURRENT BIOLOGY (2014)
Phylogenetic analysis and evolutionary origins of DNA polymerase X-family members
Rachelle J. Bienstock et al.
DNA REPAIR (2014)
Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Bypass by Human DNA Polymerase η
Amritraj Patra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
Kilian V. M. Huber et al.
NATURE (2014)
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Helge Gad et al.
NATURE (2014)
Sustained active site rigidity during synthesis by human DNA polymerase μ
Andrea F. Moon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Considerations on manganese (Mn) treatments for in vitro studies
Aaron B. Bowman et al.
NEUROTOXICOLOGY (2014)
Cellular manganese content is developmentally regulated in human dopaminergic neurons
Kevin K. Kumar et al.
SCIENTIFIC REPORTS (2014)
Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium (vol D58, pg 872, 2002)
Marjorie M. Harding
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2013)
Observing a DNA Polymerase Choose Right from Wrong
Bret D. Freudenthal et al.
CELL (2013)
Elimination and Utilization of Oxidized Guanine Nucleotides in the Synthesis of RNA and Its Precursors
Takeshi Sekiguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The Energetic Difference between Synthesis of Correct and Incorrect Base Pairs Accounts for Highly Accurate DNA Replication
Andrew C. Olson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Ribonucleotides and manganese ions improve non-homologous end joining by human Polμ
Maria Jose Martin et al.
NUCLEIC ACIDS RESEARCH (2013)
DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion
Bret D. Freudenthal et al.
NUCLEIC ACIDS RESEARCH (2013)
Watching DNA polymerase η make a phosphodiester bond
Teruya Nakamura et al.
NATURE (2012)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Oxidative stress, inflammation, and cancer How are they linked?
Simone Reuter et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine
William A. Beard et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2010)
DNA polymerases involved in the incorporation of oxidized nucleotides into DNA: Their efficiency and template base preference
Atsushi Katafuchi et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2010)
Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active site
Vinod K. Batra et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase λ
Katarzyna Bebenek et al.
EMBO REPORTS (2008)
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase γ replication fidelity
Zachary F. Pursell et al.
NUCLEIC ACIDS RESEARCH (2008)
Manganese: Recent advances in understanding its transport and neurotoxicity
Michael Aschner et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Mutagenic effects of 8-hydroxy-dGTP in live mammalian cells
Kazuya Satou et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
HKL-3000:: the integration of data reduction and structure solution -: from diffraction images to an initial model in minutes
Wladek Minor et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Small revisions to predicted distances around metal sites in proteins
MM Harding
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2006)
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-ι active site
DT Nair et al.
STRUCTURE (2006)
A closed conformation for the Pol lambda catalytic cycle
M Garcia-Diaz et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
The architecture of metal coordination groups in proteins
MM Harding
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing
DT Nair et al.
NATURE (2004)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Lack of sugar discrimination by human Pol μ requires a single glycine residue
JF Ruiz et al.
NUCLEIC ACIDS RESEARCH (2003)
Human DNA polymerase λ diverged in evolution from DNA polymerase β toward specific Mn++ dependence:: a kinetic and thermodynamic study
G Blanca et al.
BIOCHEMISTRY (2003)
Determination of Mo and Mn in human brain samples by different techniques
I Csaszma et al.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY (2003)
DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA mutator in eukaryotic cells
O Domínguez et al.
EMBO JOURNAL (2000)
8-OxodGTP incorporation by DNA polymerase β is modified by active-site residue Asn279
H Miller et al.
BIOCHEMISTRY (2000)
Repair of endogenous DNA damage
T Lindahl et al.
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (2000)
分享论文
