相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells
Andre L. Samson et al.
CELL DEATH AND DIFFERENTIATION (2021)
Location, location, location: A compartmentalized view of TNF-induced necroptotic signaling
Andre L. Samson et al.
SCIENCE SIGNALING (2021)
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
Sarah E. Garnish et al.
NATURE COMMUNICATIONS (2021)
Elevated β-cell stress levels promote severe diabetes development in mice with MODY4
Bernadette M. Trojanowski et al.
JOURNAL OF ENDOCRINOLOGY (2020)
The Killer Pseudokinase Mixed Lineage Kinase Domain-Like Protein (MLKL)
James M. Murphy
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2020)
The magnesium transporter NIPAL1 is a pancreatic islet?expressed protein that conditionally impacts insulin secretion
Yousef Manialawy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
Emma J. Petrie et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
A novel neurodegenerative spectrum disorder in patients with MLKL deficiency
Soren L. Faergeman et al.
CELL DEATH & DISEASE (2020)
The mutational constraint spectrum quantified from variation in 141,456 humans
Konrad J. Karczewski et al.
NATURE (2020)
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
Andre L. Samson et al.
NATURE COMMUNICATIONS (2020)
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
Katherine A. Davies et al.
NATURE COMMUNICATIONS (2020)
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
Joanne M. Hildebrand et al.
NATURE COMMUNICATIONS (2020)
Necroptosis in anti-viral inflammation
Himani Nailwal et al.
CELL DEATH AND DIFFERENTIATION (2019)
The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation
Haixia Xu et al.
MOLECULAR METABOLISM (2019)
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3
Emma J. Petrie et al.
CELL REPORTS (2019)
Endoplasmic reticulum stress, degeneration of pancreatic islet β-cells, and therapeutic modulation of the unfolded protein response in diabetes
Rajarshi Ghosh et al.
MOLECULAR METABOLISM (2019)
The Structural Basis of Necroptotic Cell Death Signaling
Emma J. Petrie et al.
TRENDS IN BIOCHEMICAL SCIENCES (2019)
ClinVar: improving access to variant interpretations and supporting evidence
Melissa J. Landrum et al.
NUCLEIC ACIDS RESEARCH (2018)
A rare variant in MLKL confers susceptibility to ApoE ε4-negative Alzheimer's disease in Hong Kong Chinese population
Binbin Wang et al.
NEUROBIOLOGY OF AGING (2018)
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
Emma J. Petrie et al.
NATURE COMMUNICATIONS (2018)
Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2018
DIABETES CARE (2018)
Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation
Holly Anderton et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)
Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance
Kashyap A. Patel et al.
NATURE COMMUNICATIONS (2017)
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation
Jaclyn S. Pearson et al.
NATURE MICROBIOLOGY (2017)
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure
Tammo Mueller et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
SIFT missense predictions for genomes
Robert Vaser et al.
NATURE PROTOCOLS (2016)
HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death
A. V. Jacobsen et al.
CELL DEATH & DISEASE (2016)
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance
Jeremie Gautheron et al.
NATURE COMMUNICATIONS (2016)
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop
Maria C. Tanzer et al.
BIOCHEMICAL JOURNAL (2015)
Herpes Simplex Virus Suppresses Necroptosis in Human Cells
Hongyan Guo et al.
CELL HOST & MICROBE (2015)
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL
James M. Murphy et al.
BIOCHEMICAL JOURNAL (2014)
RIPK1-and RIPK3-induced cell death mode is determined by target availability
W. D. Cook et al.
CELL DEATH AND DIFFERENTIATION (2014)
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
Huayi Wang et al.
MOLECULAR CELL (2014)
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
Marius Dannappel et al.
NATURE (2014)
The Database of Genomic Variants: a curated collection of structural variation in the human genome
Jeffrey R. MacDonald et al.
NUCLEIC ACIDS RESEARCH (2014)
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
Joanne M. Hildebrand et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
James A. Rickard et al.
ELIFE (2014)
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
Jianfeng Wu et al.
CELL RESEARCH (2013)
Biallelic PDX1 (insulin promoter factor1) mutations causing neonatal diabetes without exocrine pancreatic insufficiency
E. De Franco et al.
DIABETIC MEDICINE (2013)
The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
James M. Murphy et al.
IMMUNITY (2013)
Viral modulation of programmed necrosis
William J. Kaiser et al.
CURRENT OPINION IN VIROLOGY (2013)
Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice
Chin Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
Liming Sun et al.
CELL (2012)
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
Jie Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces
Hanka Venselaar et al.
BMC BIOINFORMATICS (2010)
A method and server for predicting damaging missense mutations
Ivan A. Adzhubei et al.
NATURE METHODS (2010)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Ben Langmead et al.
GENOME BIOLOGY (2009)
IPF-1/MODY4 gene missense mutation in an Italian family with type 2 and gestational diabetes
C Gragnoli et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2005)
Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion
M Brissova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations
J Weng et al.
DIABETOLOGIA (2001)
分享论文
