期刊
INTERNATIONAL WOUND JOURNAL
卷 19, 期 1, 页码 9-28出版社
WILEY
DOI: 10.1111/iwj.13601
关键词
chronic wound; resveratrol; scarring; skin aging; wound healing
资金
- Austrian Federal Ministry of Climate Action, Environment, Energy, Mobility, Innovation and Technology (BMK)
Resveratrol is a powerful antioxidant that may aid in wound healing and prevent skin aging. Current research suggests that resveratrol could be a feasible treatment approach, but further studies are needed to confirm its effects.
Resveratrol is a well-known antioxidant that harbours many health beneficial properties. Multiple studies associated the antioxidant, anti-inflammatory, and cell protective effects of resveratrol. These diverse effects of resveratrol are also potentially involved in cutaneous wound healing, scarring, and (photo-)aging of the skin. Hence, this review highlighted the most relevant studies involving resveratrol in wound healing, scarring, and photo-aging of the skin. A systematic review was performed and the database PubMed was searched for suitable publications. Only original articles in English that investigated the effects of resveratrol in wound healing, scarring, and (photo-)aging of the skin were analysed. The literature search yielded a total of 826 studies, but only 41 studies met the inclusion criteria. The included studies showed promising results that resveratrol might be a feasible treatment approach to support wound healing, counteract excessive scarring, and even prevent photo-aging of the skin. Resveratrol represents an interesting and promising novel therapy regime but to confirm resveratrol-associated effects, more evidence based in vitro and in vivo studies are needed.
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