期刊
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
卷 37, 期 4, 页码 -出版社
SPRINGER
DOI: 10.1007/s11274-021-03021-6
关键词
Genomics; Human pathogens; Protein microarray; Proteomics; Reverse vaccinology; Vaccine
Infectious diseases are a major cause of death and disability globally, highlighting the need for improved treatment and prevention strategies. Advanced tools such as bioinformatics, genomics, and proteomics can be utilized for rational vaccine design to combat deadly infectious diseases effectively and efficiently.
Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.
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