Patient Preferences and Treatment Decisions for Prostate Cancer: Results From A Statewide Urological Quality Improvement Collaborative

OBJECTIVES To examine the relationship between influential factors and treatment decisions among men with newly diagnosed prostate cancer (PCa). METHODS We identified men in the Michigan Urological Surgery Improvement Collaborative registry diagnosed with localized PCa between 2018-2020 who completed Personal Patient Profile-Prostate. We analyzed the proportion of active surveillance (AS) between men who stated future bladder, bowel, and sexual problems (termed influential factors) had a lot of influence on their treatment decisions versus other responses. We also assessed the relationship between influential factors, confirmatory testing results and choice of AS. RESULTS A total of 509 men completed Personal Patient Profile-Prostate. Treatment decisions aligned with influential factors for 88% of men with favorable risk and 49% with unfavorable risk PCa. A higher proportion of men who identified bladder, bowel and sexual concerns as having a lot of influence on their treatment decision chose AS, compared with men with other influential factors, although not statistically significant (44% vs 35%, P = .11). Similar results were also found when men were stratified based on PCa risk groups (favorable risk: 78% vs 67%; unfavorable risk: 17% vs 9%, respectively). Despite a small sample size, a higher proportion of men with non-reassuring confirmatory testing selected AS if influential factors had a lot of influence compared to no influence on their treatment decisions. CONCLUSION Men's concerns for future bladder, bowel, and sexual function problems, as elicited by a decision aid, may help explain treatment selection that differs from traditional clinical recommendation. (C) 2021 Elsevier Inc.

Automated summary

This study examined the relationship between influential factors and treatment decisions among men with newly diagnosed prostate cancer. It found that men's concerns for future bladder, bowel, and sexual function problems may influence their treatment selection, especially for those with lower risk prostate cancer. Men who identified bladder, bowel, and sexual concerns as having a lot of influence on their treatment decision were more likely to choose active surveillance, indicating a potential shift from traditional clinical recommendations.