相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The Neuroimmunology of Chronic Pain: From Rodents to Humans
Peter M. Grace et al.
JOURNAL OF NEUROSCIENCE (2021)
Oxidative stress and inflammation in the evolution of heart failure: From pathophysiology to therapeutic strategies
Alberto Aimo et al.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)
Long term multiple sclerosis drug delivery using dendritic polyglycerol flower-like microspheres
Priscila Veloso da Silva et al.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION (2020)
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Regulates Epidermal Keratinization under Psoriatic Skin Inflammation
Tatsuya Ogawa et al.
AMERICAN JOURNAL OF PATHOLOGY (2020)
Oral Dimethyl Fumarate Reduces Peripheral Neuropathic Pain in Rodents via NFE2L2 Antioxidant Signaling
Jiahe Li et al.
ANESTHESIOLOGY (2020)
Diroximel Fumarate Demonstrates an Improved Gastrointestinal Tolerability Profile Compared with Dimethyl Fumarate in Patients with Relapsing-Remitting Multiple Sclerosis: Results from the Randomized, Double-Blind, Phase III EVOLVE-MS-2 Study
Robert T. Naismith et al.
CNS DRUGS (2020)
Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
Giovanna Casili et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Neuroprotective effect of dimethyl fumarate on cognitive impairment induced by ischemic stroke
Xiaowen Hou et al.
ANNALS OF TRANSLATIONAL MEDICINE (2020)
Dimethyl fumarate ameliorates diabetes-associated vascular complications through ROS-TXNIP-NLRP3 inflammasome pathway
Fatma M. Amin et al.
LIFE SCIENCES (2020)
Monomethyl fumarate has better gastrointestinal tolerability profile compared with dimethyl fumarate
Daniel Wynn et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2020)
Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain
Serena Boccella et al.
FASEB JOURNAL (2019)
AMPK activation attenuates inflammatory pain through inhibiting NF-B activation and IL-1 expression
Hong-Chun Xiang et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Dimethyl fumarate, a two-edged drug: Current status and future directions
Nathaniel Edward Bennett Saidu et al.
MEDICINAL RESEARCH REVIEWS (2019)
Pros and Cons of Clinically Relevant Methods to Assess Pain in Rodents
Anke Tappe-Theodor et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2019)
Dimethyl Fumarate Attenuates Oxaliplatin-Induced Peripheral Neuropathy without Affecting the Anti-tumor Activity of Oxaliplatin in Rodents
Anna Miyagi et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2019)
Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes
Karl E. Carlstrom et al.
NATURE COMMUNICATIONS (2019)
Improving the Gastrointestinal Tolerability of Fumaric Acid Esters: Early Findings on Gastrointestinal Events with Diroximel Fumarate in Patients with Relapsing-Remitting Multiple Sclerosis from the Phase 3, Open-Label EVOLVE-MS-1 Study
Michael J. Palte et al.
ADVANCES IN THERAPY (2019)
The Effects of Dimethyl Fumarate on Atherosclerosis in the Apolipoprotein E-Deficient Mouse Model with Streptozotocin-Induced Hyperglycemia Mediated By the Nuclear Factor Erythroid 2-Related Factor 2/Antioxidant Response Element (Nrf2/ARE) Signaling Pathway
Man Luo et al.
MEDICAL SCIENCE MONITOR (2019)
Therapeutic targeting of the NRF2 and KEAP 1 partnership in chronic diseases
Antonio Cuadrado et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis
Christina Lueckel et al.
NATURE COMMUNICATIONS (2019)
No evidence for interactions of dimethylfumarate (DMF) and its main metabolite monomethylfumarate (MMF) with human cytochrome P450 (CYP) enzymes and the P-glycoprotein (P-gp) drug transporter
Jordi Aubets et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2019)
Large animal models of stroke and traumatic brain injury as translational tools
Annabel J. Sorby-Adams et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2018)
Dimethyl fumarate (DMF) vs. monoethyl fumarate (MEF) salts for the treatment of plaque psoriasis: a review of clinical data
Lilla Landeck et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2018)
Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer's disease
Irena Majkutewicz et al.
BRAIN RESEARCH (2018)
A review of the mechanisms of action of dimethylfumarate in the treatment of psoriasis
Juergen Brueck et al.
EXPERIMENTAL DERMATOLOGY (2018)
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits following systemic immune challenge
Hallel C. Paraiso et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?
Robert P. Yezierski et al.
JOURNAL OF PAIN (2018)
Dimethyl fumarate ameliorates chemotherapy agent-induced neurotoxicity in vitro
Takehiro Kawashiri et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2018)
Sensory profiling in animal models of neuropathic pain: a call for back-translation
Andrew S. C. Rice et al.
PAIN (2018)
THE KEAP1-NRF2 SYSTEM: A THIOL-BASED SENSOR-EFFECTOR APPARATUS FOR MAINTAINING REDOX HOMEOSTASIS
Masayuki Yamamoto et al.
PHYSIOLOGICAL REVIEWS (2018)
Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity
Michael D. Kornberg et al.
SCIENCE (2018)
Protection by dimethyl fumarate against diabetic cardiomyopathy in type 1 diabetic mice likely via activation of nuclear factor erythroid-2 related factor 2
Xinyue Hu et al.
TOXICOLOGY LETTERS (2018)
Lysine-Based C-60-Fullerene Nanoconjugates for Monomethyl Fumarate Delivery: A Novel Nanomedicine for Brain Cancer Cells
Manish Kumar et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)
Emerging Understanding of the Mechanism of Action for Dimethyl Fumarate in the Treatment of Multiple Sclerosis
Elizabeth A. Mills et al.
FRONTIERS IN NEUROLOGY (2018)
Lysine-Based C-60-Fullerene Nanoconjugates for Monomethyl Fumarate Delivery: A Novel Nanomedicine for Brain Cancer Cells
Manish Kumar et al.
ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)
Dimethyl fumarate interferes with MyD88-dependent toll-like receptor signalling pathway in isoproterenol-induced cardiac hypertrophy model
Asmaa A. Ahmed et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2018)
Clinical use of dimethyl fumarate in moderate-to-severe plaque-type psoriasis: a European expert consensus
U. Mrowietz et al.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2018)
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
Spencer L. G. James et al.
LANCET (2018)
Alzheimer's disease: experimental models and reality
Eleanor Drummond et al.
ACTA NEUROPATHOLOGICA (2017)
Fumarate decreases edema volume and improves functional outcome after experimental stroke
Bettina Hjelm Clausen et al.
EXPERIMENTAL NEUROLOGY (2017)
Animal models of α-synucleinopathy for Parkinson disease drug development
James B. Koprich et al.
NATURE REVIEWS NEUROSCIENCE (2017)
Monomethyl fumarate inhibits pain behaviors and amygdala activity in a rat arthritis model
Hyunyoung Kim et al.
PAIN (2017)
Hydroxy-Carboxylic Acid Receptor Actions in Metabolism
Stefan Offermanns
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)
The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2
Michela Campolo et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Enhanced Brain Delivery of Dimethyl Fumarate Employing Tocopherol-Acetate-Based Nanolipidic Carriers: Evidence from Pharmacokinetic, Biodistribution, and Cellular Uptake Studies
Pramod Kumar et al.
ACS CHEMICAL NEUROSCIENCE (2017)
Immunometabolism governs dendritic cell and macrophage function
Luke A. J. O'Neill et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms
Melanie S. Brennan et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease
Isabel Lastres-Becker et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Dimethyl fumarate attenuates intracerebroventricular streptozotocin-induced spatial memory impairment and hippocampal neurodegeneration in rats
Irena Majkutewicz et al.
BEHAVIOURAL BRAIN RESEARCH (2016)
Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats
Ruihe Lin et al.
JOURNAL OF NEUROINFLAMMATION (2016)
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease
Manuj Ahuja et al.
JOURNAL OF NEUROSCIENCE (2016)
Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2
Ulf Schulze-Topphoff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Nitroxidative Signaling Mechanisms in Pathological Pain
Peter M. Grace et al.
TRENDS IN NEUROSCIENCES (2016)
Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice
Yang Yao et al.
TRANSLATIONAL STROKE RESEARCH (2016)
Characterizing absolute lymphocyte count profiles in dimethyl fumarate-treated patients with MS Patient management considerations
Robert J. Fox et al.
NEUROLOGY-CLINICAL PRACTICE (2016)
Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS
Benedetta Parodi et al.
ACTA NEUROPATHOLOGICA (2015)
Impact of fumaric acid esters on cardiovascular risk factors and depression in psoriasis: a prospective pilot study
Astrid Schmieder et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2015)
Dissecting molecular cross-talk between Nrf2 and NF-kappa B response pathways
Joanna D. Wardyn et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2015)
Effect of Aspirin Pretreatment or Slow Dose Titration on Flushing and Gastrointestinal Events in Healthy Volunteers Receiving Delayed-release Dimethyl Fumarate
John O'Gorman et al.
CLINICAL THERAPEUTICS (2015)
Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity
Reiner Kunze et al.
EXPERIMENTAL NEUROLOGY (2015)
Translating dosages from animal models to human clinical trials-revisiting body surface area scaling
Otis L. Blanchard et al.
FASEB JOURNAL (2015)
Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage
Loretta O. Iniaghe et al.
NEUROBIOLOGY OF DISEASE (2015)
DIMETHYL FUMARATE ATTENUATES 6-OHDA-INDUCED NEUROTOXICITY IN SH-SY5Y CELLS AND IN ANIMAL MODEL OF PARKINSON'S DISEASE BY ENHANCING NRF2 ACTIVITY
X. Jing et al.
NEUROSCIENCE (2015)
Dimethyl Fumarate Protects Brain From Damage Produced by Intracerebral Hemorrhage by Mechanism Involving Nrf2
Xiurong Zhao et al.
STROKE (2015)
Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain
N. Percie du Sert et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
BG-12 (dimethyl fumarate): a review of mechanism of action, efficacy, and safety
Robert J. Fox et al.
CURRENT MEDICAL RESEARCH AND OPINION (2014)
Activation of Nrf2 by dimethyl fumarate improves vascular calcification
Chae-Myeong Ha et al.
VASCULAR PHARMACOLOGY (2014)
Managing flushing and gastrointestinal events associated with delayed-release dimethyl fumarate: Experiences of an international panel
J. Theodore Phillips et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2014)
Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms
Chang Joo Oh et al.
REDOX BIOLOGY (2014)
Pathological pain and the neuroimmune interface
Peter M. Grace et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Detection of fumarate-glutathione adducts in the portal vein blood of rats: evidence for rapid dimethylfumarate metabolism
Stefan Dibbert et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2013)
GPR109A and Vascular Inflammation
Joshua T. Chai et al.
CURRENT ATHEROSCLEROSIS REPORTS (2013)
Up-down Regulation of HO-1 and iNOS Gene Expressions by Ethyl Pyruvate via Recruiting p300 to Nrf2 and Depriving It from p65
Seung-Woo Kim et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Animal Models of Atherosclerosis
Godfrey S. Getz et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway
Houman Ashrafian et al.
CELL METABOLISM (2012)
Intracerebral haemorrhage: mechanisms of injury and therapeutic targets
Richard F. Keep et al.
LANCET NEUROLOGY (2012)
Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke
Rakesh Khatri et al.
NEUROLOGY (2012)
Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis
Ralf Gold et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Animal Models of Alzheimer Disease
Frank M. LaFerla et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Fumarates Promote Cytoprotection of Central Nervous System Cells against Oxidative Stress via the Nuclear Factor (Erythroid-Derived 2)-Like 2 Pathway
Robert H. Scannevin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1
Shao Xia Lin et al.
ASN NEURO (2011)
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
Ralf A. Linker et al.
BRAIN (2011)
Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease
Susan Duty et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Crosstalk of reactive oxygen species and NF-kappa B signaling
Michael J. Morgan et al.
CELL RESEARCH (2011)
Cyclic AMP: a selective modulator of NF-κB action
Sarah Gerlo et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells
Kamran Ghoreschi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Treatment of lupus erythematosus with fumaric acid ester derivatives: two case-reports
Deepak MW Balak et al.
Journal of Translational Medicine (2011)
Ischemia and reperfusion-from mechanism to translation
Holger K. Eltzschig et al.
NATURE MEDICINE (2011)
Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients
Martin Rostami-Yazdi et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2010)
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
Ananta Paine et al.
BIOCHEMICAL PHARMACOLOGY (2010)
β-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice
Robert W. Walters et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Detection of Metabolites of Fumaric Acid Esters in Human Urine: Implications for Their Mode of Action
Martin Rostami-Yazdi et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2009)
Animal models of pain: progress and challenges
Jeffrey S. Mogil
NATURE REVIEWS NEUROSCIENCE (2009)
Heme oxygenase-1: from biology to therapeutic potential
Miguel P. Soares et al.
TRENDS IN MOLECULAR MEDICINE (2009)
The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist
Hua Tang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis
Wenge Li et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Dimethyl fumarate, a small molecule drug for psoriasis, inhibits Nuclear Factor-κB and reduces myocardial infarct size in rats
Silvia Meili-Butz et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Dose translation from animal to human studies revisited
Shannon Reagan-Shaw et al.
FASEB JOURNAL (2008)
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Ludwig Kappos et al.
LANCET (2008)
Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine - Preparation of S-substituted thiosuccinic acid esters
Thomas J. Schmidt et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Oral fumaric acid esters for the treatment of active multiple sclerosis:: an open-label, baseline-controlled pilot study
S. Schimrigk et al.
EUROPEAN JOURNAL OF NEUROLOGY (2006)
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
DS Witherow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Pharmacokinetics of oral fumarates in healthy subjects
NHR Litjens et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2004)
Design of ester prodrugs to enhance oral absorption of poorly permeable compounds: Challenges to the discovery scientist
K Beaumont et al.
CURRENT DRUG METABOLISM (2003)
Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters
D Werdenberg et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2003)
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
S Tunaru et al.
NATURE MEDICINE (2003)
分享论文
