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Article
Medicine, General & Internal
Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults
R. Libster et al.
Summary: A randomized, double-blind, placebo-controlled trial of convalescent plasma with high IgG titers against SARS-CoV-2 in older adult patients within 72 hours after the onset of mild Covid-19 symptoms found that early administration of high-titer convalescent plasma reduced the progression of Covid-19 in mildly ill infected older adults.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Review
Medicine, General & Internal
Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19 A Systematic Review and Meta-analysis
Perrine Janiaud et al.
Summary: Convalescent plasma treatment showed no significant decrease in all-cause mortality or benefit for other clinical outcomes compared to placebo or standard of care. The certainty of the evidence ranged from low to moderate for all-cause mortality and remained low for other outcomes.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)
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