Application of allylic amine formation from aziridine-2-ol under Appel reaction condition: Synthesis of N-(tert-butoxycarbonyl)-D-vinyl glycine methyl ester

PPh3/I-2/imidazolde mediated allyl amine formation from aziridine-2-alcohol was explored for the synthesis of N-(tert-butoxycarbonyl)-D-vinyl glycine methyl ester. (C) 2021 Published by Elsevier Ltd.

Automated summary

The formation of allyl amine from aziridine-2-alcohol was achieved through PPh3/I-2/imidazolde mediation for the synthesis of N-(tert-butoxycarbonyl)-D-vinyl glycine methyl ester.